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Alexey Berezhnoy
Observed names:
A Berezhnoy,
A. Berezhnoy,
A. E. Berezhnoy,
Aleksey E. Berezhnoy
Institution:
Zymeworks (Canada)
Observed institutions:
Russian Academy of Sciences,
University of Miami,
Zymeworks (Canada),
University of Miami Health System,
MacroGenics (United States),
Institute of Gene Biology,
CytomX Therapeutics (United States),
Sylvester Comprehensive Cancer Center
show all 8
ORCID:
0000-0002-7886-5181
Observed ORCID:
0000-0002-7886-5181
OpenAlex ID:
A5102822234
Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery
2015
·
Jan Hoinka
, Alexey Berezhnoy
, et al.
·
Nucleic Acids Research
·
127
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity
2013
·
Alexey Berezhnoy
, Iris Castro
, et al.
·
Journal of Clinical Investigation
·
123
PDF
Isolation and Optimization of Murine IL-10 Receptor Blocking Oligonucleotide Aptamers Using High-throughput Sequencing
2012
·
Alexey Berezhnoy
, C. Andrew Stewart
, et al.
·
Molecular Therapy
·
120
AptaCluster – A Method to Cluster HT-SELEX Aptamer Pools and Lessons from Its Application
2014
·
Jan Hoinka
, Alexey Berezhnoy
, et al.
·
Lecture notes in computer science
·
111
Targeting 4-1BB Costimulation to the Tumor Stroma with Bispecific Aptamer Conjugates Enhances the Therapeutic Index of Tumor Immunotherapy
2014
·
Brett Schrand
, Alexey Berezhnoy
, et al.
·
Cancer Immunology Research
·
98
PDF
Identifying high-affinity aptamer ligands with defined cross-reactivity using high-throughput guided systematic evolution of ligands by exponential enrichment
2015
·
Agata Levay
, Randall Brenneman
, et al.
·
Nucleic Acids Research
·
91
PDF
Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity
2019
·
Greta Garrido
, Brett Schrand
, et al.
·
Nature Communications
·
71
PDF
Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule
2020
·
Alexey Berezhnoy
, Bradley J. Sumrow
, et al.
·
Cell Reports Medicine
·
58
Aptamer-Targeted Attenuation of IL-2 Signaling in CD8 + T Cells Enhances Antitumor Immunity
2017
·
Anugraha Rajagopalan
, Alexey Berezhnoy
, et al.
·
Molecular Therapy
·
53
PDF
Reducing Toxicity of Immune Therapy Using Aptamer-Targeted Drug Delivery
2015
·
Eli Gilboa
, Alexey Berezhnoy
, et al.
·
Cancer Immunology Research
·
44
PDF
Thermal Stability of siRNA Modulates Aptamer- conjugated siRNA Inhibition
2012
·
Alexey Berezhnoy
, Randall Brenneman
, et al.
·
Molecular Therapy — Nucleic Acids
·
36
PDF
Reducing toxicity of 4–1BB costimulation: targeting 4–1BB ligands to the tumor stroma with bi-specific aptamer conjugates
2015
·
B Schrand
, A Berezhnoy
, et al.
·
OncoImmunology
·
25
PDF
Aptamer-mediated transcriptional gene silencing of Foxp3 inhibits regulatory T cells and potentiates antitumor response
2021
·
Andrea J. Manrique-Rincón
, Luciana P. Ruas
, et al.
·
Molecular Therapy — Nucleic Acids
·
15
Tracking Ku antigen levels in cell extracts with DNA containing abasic sites
2009
·
Ekaterina S. Ilina
, Svetlana N. Khodyreva
, et al.
·
Mutation research. Fundamental and molecular mechanisms of mutagenesis
·
12
706 Conditional cytokine therapeutics for tumor-selective biological activity: preclinical characterization of a dual-masked IFN-a2b
2021
·
Alexey Berezhnoy
, Hsin Wang
, et al.
·
Journal for ImmunoTherapy of Cancer
·
7
PDF
Abstract 2288: Investigational CD25 x CTLA-4 bispecific DART® molecule for depletion of tumor infiltrating Tregs via an enhanced Fc-dependent effector mechanism
2020
·
Alexey Berezhnoy
, Kalpana Shah
, et al.
·
Cancer Research
·
5
A phase I, first-in-human, open label, dose-escalation and cohort expansion study of MGD019, a bispecific DART protein binding PD-1 and CTLA-4 in patients with unresectable or metastatic neoplasms.
2019
·
Jason J. Luke
, Manish Sharma
, et al.
·
Journal of Clinical Oncology
·
3
Late Breaking Abstract - ZW1528: A dual-targeting bispecific antibody to broadly suppress airway inflammation by inhibiting IL-4Ra and IL-33 pathways
2025
·
Blair Hardman
, Maya C. Poffenberger
, et al.
·
European Respiratory Journal
·
2
682 Antibody-mediated blockade of interleukin-10 receptor-alpha promotes the activation of immune cells from in vitro dissociated tumor samples
2020
·
Alexey Berezhnoy
, Kalpana Shah
, et al.
·
Journal for ImmunoTherapy of Cancer
·
2
1078 Conditionally activatable interferon-alpha 2b improves tolerability and exhibits preferential activity in tumors
2022
·
Alexey Berezhnoy
, Hsin Wang
, et al.
·
Journal for ImmunoTherapy of Cancer
·
1
PDF
Abstract 2071: Probody-interferon-alpha 2b combines antitumor activity with improved tolerability
2022
·
Alexey Berezhnoy
, Hsin Wang
, et al.
·
Cancer Research
·
1
High-dose γ-irradiation enhances the expression of a transgene controlled by the immediate-early CMV promoter in stably transfected tumor cells
2008
·
A. E. Berezhnoy
, A. A. Wainson
, et al.
·
Molecular Biology
·
1
1064 Characterization of preclinical anti-tumor and pharmacodynamic activity in response to conditionally active IFNa with or without checkpoint blockade
2023
·
Benjamin Povinelli
, Kamaljeet Kaur
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
Abstract 264: Vaccination against neoantigens induced in future tumors in the setting of recurrence and premalignancy
2018
·
Greta Garrido Hidalgo
, Brett Schrand
, et al.
·
Cancer Research
Abstract 2617: Inducing neoantigens in therapeutic and prophylactic cancer immunotherapy
2017
·
Greta Garrido Hidalgo
, Agata Levay
, et al.
·
Cancer Research
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Works count:
34
Citation count:
1,006
H-index:
13
I10-index:
14
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