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Ashley M. Smith
Observed names:
A. Smith,
A.M. Smith,
Ashley M Smith,
Ashley Marie Smith,
Ashley Smith
Institution:
Kiyatec (United States)
Observed institutions:
University of Wyoming,
Medical University of South Carolina,
Genentech,
Kiyatec (United States),
James H. Quillen VA Medical Center,
Pharmacyclics (United States),
CFD Research Corporation (United States)
show all 7
ORCID:
0000-0001-6971-7075
Observed ORCID:
0000-0001-6971-7075
OpenAlex ID:
A5102920492
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
2010
·
Lee A. Honigberg
, Ashley M. Smith
, et al.
·
Proceedings of the National Academy of Sciences
·
1,588
Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics
2014
·
Kristin R Wildsmith
, Stephen P Schauer
, et al.
·
Molecular Neurodegeneration
·
141
PDF
Prospective Validation of an Ex Vivo, Patient-Derived 3D Spheroid Model for Response Predictions in Newly Diagnosed Ovarian Cancer
2019
·
Stephen Shuford
, Christine Wilhelm
, et al.
·
Scientific Reports
·
64
PDF
Intergenerational impact of maternal overnutrition and obesity throughout pregnancy in sheep on metabolic syndrome in grandsons and granddaughters
2017
·
C.L. Pankey
, M.W. Walton
, et al.
·
Domestic Animal Endocrinology
·
39
Adhesion patterns in the microvasculature are dependent on bifurcation angle
2015
·
Giuseppina Lamberti
, Fariborz Soroush
, et al.
·
Microvascular Research
·
39
Tim-3 alters the balance of IL-12/IL-23 and drives TH17 cells: Role in hepatitis B vaccine failure during hepatitis C infection
2013
·
Jia M. Wang
, Cheng J. Ma
, et al.
·
Vaccine
·
39
A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
2021
·
Megan R. Reed
, A. Geoffrey Lyle
, et al.
·
Cells
·
28
PDF
Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay
2021
·
Stephen Shuford
, Lindsay Lipinski
, et al.
·
Neuro-Oncology Advances
·
23
PDF
Maternal obesity programs reduced leptin signaling in the pituitary and altered GH/IGF1 axis function leading to increased adiposity in adult sheep offspring
2017
·
Nuermaimaiti Tuersunjiang
, John F. Odhiambo
, et al.
·
PLoS ONE
·
19
PDF
A Phase I Dose Escalation Study of the Btk Inhibitor PCI-32765 in Relapsed and Refractory B Cell Non-Hodgkin Lymphoma and Use of a Novel Fluorescent Probe Pharmacodynamic Assay.
2009
·
Daniel A Pollyea
, Sonali Smith
, et al.
·
Blood
·
13
A heretical view: rather than a solely placental protective function, placental 11β hydroxysteroid dehydrogenase 2 also provides substrate for fetal peripheral cortisol synthesis in obese pregnant ewes
2020
·
Adel B. Ghnenis
, John F. Odhiambo
, et al.
·
Journal of Developmental Origins of Health and Disease
·
9
Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity
2020
·
Teresa L. Serafim
, Teresa Cunha‐Oliveira
, et al.
·
European Journal of Clinical Investigation
·
8
Targeting Btk in Lymphoma: PCI-32765 Inhibits Tumor Growth in Mouse Lymphoma Models and a Fluorescent Analog of PCI-32765 Is an Active-Site Probe That Enables Assessment of Btk Inhibition In Vivo.
2007
·
Lee A. Honigberg
, Ashley M. Smith
, et al.
·
Blood
·
3
Safety and efficacy of single‐agent ibrutinib in patients with relapsed/refractory ( R/R ) marginal zone lymphoma ( MZL ): A multicenter, open‐label, phase 2 study
2017
·
G.P. Collins
, A. Noy
, et al.
·
Hematological Oncology
·
2
PDF
Abstract 1121: Profiling patient-specific glioblastoma drug response in vitro using complex 3D microtumors
2018
·
Ashley M. Smith
, Melissa Millard
, et al.
·
Cancer Research
·
1
Levels of tonic BCR signaling predict response to the Btk inhibitor PCI-32765
2008
·
Lee Honigberg
, Jun Chen
, et al.
·
Cancer Research
·
1
Innv-33. Functional Ex Vivo Testing Prospectively Identifies Newly Diagnosed Glioblastoma Patients Sensitive to Temozolomide Treatment Irrespective of Mgmt Methylation Status
2022
·
Tessa DesRochers
, Lindsay Lipinski
, et al.
·
Neuro-Oncology
PDF
Clrm-19 Using Functional Precision Medicine to Guide Clinical Trial Enrollment in Gbm
2022
·
Aubrey Ledford
, Ashley Smith
, et al.
·
Neuro-Oncology Advances
PDF
Clinical application of a functional 3D ex vivo test to predict therapeutic response in patients with HGG: A progression-free survival analysis.
2022
·
Lindsay J Lipinski
, Ajay Prakash Abad
, et al.
·
Journal of Clinical Oncology
Innv-14. Predictive Utility of Temozolomide Response as Determined by 3d Ex-vivo Cell Culture Assays in Newly Diagnosed Glioblastoma: a Single Institution Case Series Evaluating Progression Free Survival
2021
·
Lindsay J Lipinski
, Ajay Abad
, et al.
·
Neuro-Oncology
PDF
Innv-16. Clinical Applicability of Individualized Drug Response Profiling Utilizing Ex-vivo Tissue-derived 3d Cell Culture Assays in High-grade Glioma: a Single Institution Case Series Using 3d-predict Results
2020
·
Lindsay Lipinski
, Ajay Abad
, et al.
·
Neuro-Oncology
PDF
Tmod-42. Prospective Validation of an Ex Vivo 3d Assay for Prediction of Temozolomide Response in Glioblastoma
2019
·
Ashley Smith
, Lillia Holmes
, et al.
·
Neuro-Oncology
PDF
Abstract 2240: Redefining personalized medicine by drug response profiling of patient-derived spheroids
2019
·
Stephen Shuford
, Christine Wilhelm
, et al.
·
Cancer Research
Abstract 53: Ex vivo models of glioblastoma: a comparison of 3D tissues and patient-derived xenografts to clinical response
2019
·
Ashley M. Smith
, Lillia Holmes
, et al.
·
Cancer Research
Abstract 53:Ex vivomodels of glioblastoma: a comparison of 3D tissues and patient-derived xenografts to clinical response
2019
·
Ashley M. Smith
, Lillia Holmes
, et al.
·
Tumor Biology
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Works count:
29
Citation count:
2,012
H-index:
10
I10-index:
10
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