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Author

Ke Gong

Observed names: G. Ke, Gong, Ke, K Gong, Ke Wei Gong
Institution: Wuhan University
ORCID: 0000-0001-7746-2615
Observed ORCIDs: 0000-0001-7746-2615, 0000-0002-8355-6770
OpenAlex ID: A5102928705
Ligand-Independent EGFR Signaling
2015 · Gao Guo, Ke Gong, et al. · Cancer Research · 196
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma
2011 · Ke Gong, Wenhua Li · Free Radical Biology and Medicine · 149
Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma
2010 · Chaoyang Liu, Ke Gong, et al. · International Journal of Cancer · 137
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Autophagy-related Gene 7 (ATG7) and Reactive Oxygen Species/Extracellular Signal-regulated Kinase Regulate Tetrandrine-induced Autophagy in Human Hepatocellular Carcinoma
2012 · Ke Gong, Chao Chen, et al. · Journal of Biological Chemistry · 136
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CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells
2012 · Ke Gong, Jia Xie, et al. · Biochemical Journal · 130
A TNF–JNK–Axl–ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma
2017 · Gao Guo, Ke Gong, et al. · Nature Neuroscience · 114
Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling
2013 · J Wan, T Liu, et al. · British Journal of Cancer · 100
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TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer
2018 · Ke Gong, Gao Guo, et al. · Journal of Clinical Investigation · 98
EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer
2020 · Ke Gong, Gao Guo, et al. · Nature Cancer · 90
Tumor necrosis factor in lung cancer: Complex roles in biology and resistance to treatment
2020 · Ke Gong, Gao Guo, et al. · Neoplasia · 86
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Identification of the Jak/Stat Proteins as Novel Downstream Targets of EphA4 Signaling in Muscle
2004 · Kwok-On Lai, Yu Chen, et al. · Journal of Biological Chemistry · 81
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Cyclin-Dependent Kinase 5 Supports Neuronal Survival through Phosphorylation of Bcl-2
2008 · Zelda H. Cheung, Ke Gong, et al. · Journal of Neuroscience · 75
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Pctaire1 Phosphorylates N-Ethylmaleimide-sensitive Fusion Protein
2006 · Yuxin Liu, Kai Cheng, et al. · Journal of Biological Chemistry · 71
P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in Human colon Cancer cells
2012 · Yao Zhan, Ke Gong, et al. · Free Radical Biology and Medicine · 70
Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma
2014 · Ke Gong, Zhenxing Zhang, et al. · European Journal of Pharmacology · 46
EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation
2022 · Gao Guo, Ke Gong, et al. · Nature Cell Biology · 45
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma
2019 · Gao Guo, Ke Gong, et al. · Neuro-Oncology · 37
Itraconazole Exerts Its Antitumor Effect in Esophageal Cancer By Suppressing the HER2/AKT Signaling Pathway
2021 · Wei Zhang, Ankur S. Bhagwath, et al. · Molecular Cancer Therapeutics · 33
Solution Structure of the C-terminal Domain of the Ciliary Neurotrophic Factor (CNTF) Receptor and Ligand Free Associations among Components of the CNTF Receptor Complex
2003 · David Man, Wei He, et al. · Journal of Biological Chemistry · 20
ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression
2025 · Mengyao Wang, Xiao Wen, et al. · Nature Communications · 18
C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis
2012 · Hai‐Ming Hu, Yicheng Chen, et al. · The FASEB Journal · 17
Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids
2021 · Ke Gong, Gao Guo, et al. · Nature Communications · 14
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Sj7170, a Unique Dual-function Peptide with a Specific α-Chymotrypsin Inhibitory Activity and a Potent Tumor-activating Effect from Scorpion Venom
2014 · Yu Song, Ke Gong, et al. · Journal of Biological Chemistry · 14
Decreased LDHB expression in breast tumor cells causes NK cell activation and promotes tumor progression
2024 · Zhihong Luo, Xiaohua Huang, et al. · Cancer Biology and Medicine · 12
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Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro
2002 · Wei He, Ke Gong, et al. · FEBS Letters · 12
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Works count: 49
Citation count: 1,818
H-index: 19
I10-index: 26
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