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Dmytro S. Lesyk
Observed names:
Dmytro Lesyk,
Lesyk, Dmytro
Institutions:
Taras Shevchenko National University of Kyiv,
Enamine (Ukraine)
Observed institutions:
National Academy of Sciences of Ukraine,
Taras Shevchenko National University of Kyiv,
Institute of Bioorganic Chemistry and Petrochemistry V.P. Kukhar,
Enamine (Ukraine)
ORCID:
0009-0001-3391-5165
Observed ORCID:
0009-0001-3391-5165
OpenAlex ID:
A5103017613
1,2-Disubstituted bicyclo[2.1.1]hexanes as saturated bioisosteres of ortho -substituted benzene
2023
·
Aleksandr Denisenko
, Pavel Garbuz
, et al.
·
Chemical Science
·
102
PDF
1‐Azaspiro[3.3]heptane as a Bioisostere of Piperidine**
2023
·
Alexander A. Kirichok
, Hennadii Tkachuk
, et al.
·
Angewandte Chemie International Edition
·
57
PDF
2‐Oxabicyclo[2.1.1]hexanes: Synthesis, Properties, and Validation as Bioisosteres of ortho‐ and meta‐Benzenes
2024
·
Vadym V. Levterov
, Yaroslav Panasiuk
, et al.
·
Angewandte Chemie International Edition
·
50
“Angular” Spirocyclic Azetidines: Synthesis, Characterization, and Evaluation in Drug Discovery
2024
·
Alexander A. Kirichok
, Hennadii Tkachuk
, et al.
·
Angewandte Chemie International Edition
·
37
CF3-Cyclobutanes: Synthesis, Properties, and Evaluation as a Unique tert-Butyl Group Analogue
2024
·
Volodymyr Ahunovych
, Anton A. Klipkov
, et al.
·
JACS Au
·
26
3,3‐Difluorooxetane–A Versatile Functional Group for Bioisosteric Replacements in Drug Discovery
2024
·
Oleksandr S. Liashuk
, Anastasiya Fedinchyk
, et al.
·
Chemistry - A European Journal
·
22
Lipophilicity effects of monofluorination at the tertiary aliphatic carbon as a function of α-substituent
2024
·
Kostiantyn P. Melnykov
, Oleksandr S. Liashuk
, et al.
·
Journal of Fluorine Chemistry
·
12
Physicochemical and Biological Evaluation of gem ‐Difluorinated Saturated Oxygen Heterocycles as Bioisosteres for Drug Discovery
2024
·
Kostiantyn P. Melnykov
, Oleksandr S. Liashuk
, et al.
·
Chemistry - A European Journal
·
11
PDF
Acidity of saturated (hetero)cyclic α-fluoro carboxylic acids and lipophilicity of their amide derivatives
2024
·
Oleksii Pidvyshennyi
, Kostiantyn P. Melnykov
, et al.
·
Journal of Fluorine Chemistry
·
11
Synthesis and Physicochemical Properties of Functionalized cis– 2‐((Fluoro)Alkyl)Cyclobutanes
2025
·
Anton V. Chernykh
, Oleksandr S. Liashuk
, et al.
·
ChemPlusChem
·
9
PDF
Fluorine‐Containing 6‐Azabicyclo[3.1.1]heptanes: Bicyclic Piperidine Analogs for Drug Discovery
2025
·
Anton V. Chernykh
, Oleksandr S. Liashuk
, et al.
·
European Journal of Organic Chemistry
·
9
4-Azaspiro[2.3]hexane, an Overlooked Piperidine Isostere: Multigram Synthesis and Physicochemical and Structural Evaluation
2024
·
Sergiy Galavskyy
, Anton Chernykh
, et al.
·
The Journal of Organic Chemistry
·
8
Basicity and Lipophilicity of gem ‐Difluorinated Saturated Bicyclic Amines: Advanced Building Blocks for Drug Discovery
2025
·
Oleksandr S. Liashuk
, Bohdan Moroz
, et al.
·
European Journal of Organic Chemistry
·
6
PDF
“Angular” Spirocyclic Azetidines: Synthesis, Characterization, and Evaluation in Drug Discovery
2024
·
Alexander A. Kirichok
, Hennadii Tkachuk
, et al.
·
Angewandte Chemie
·
6
2‐Oxabicyclo[2.1.1]hexanes: Synthesis, Properties, and Validation as Bioisosteres of ortho‐ and meta‐Benzenes
2024
·
Vadym V. Levterov
, Yaroslav Panasiuk
, et al.
·
Angewandte Chemie
·
5
Synthesis and Physicochemical Characterization of 5‐Trifluoromethyl‐Substituted Tetrahydrofurans and Tetrahydrothiophenes
2025
·
Mykhailo O. Redka
, Nazar Dovhaniuk
, et al.
·
European Journal of Organic Chemistry
·
4
PDF
1‐Azaspiro[3.3]heptane as a Bioisostere of Piperidine**
2023
·
Alexander A. Kirichok
, Hennadii Tkachuk
, et al.
·
Angewandte Chemie
·
4
PDF
Synthesis, Physicochemical Properties, and Computational Analysis of Tris(fluoromethyl)Alkyl Building Blocks
2026
·
Denys Klyukovskyi
, Oleksandr S. Liashuk
, et al.
·
Chemistry - A European Journal
·
3
PDF
Shake-Flask Aqueous Solubility assay (Kinetic solubility) v1
2024
·
Dmytro Lesyk
, Yurii Kheilik
·
3
PDF
Physicochemical Properties of α‐Fluoroalkyl‐Substituted Cycloalkylamines and Amino Acids
2026
·
Kostiantyn P. Melnykov
, Oleksandr S. Liashuk
, et al.
·
ChemMedChem
·
1
PDF
α-Fluoroalkyl-substituted cyclopentane building blocks for drug discovery
2026
·
Bohdan V. Bobovskyi
, Oleksandr Demchuk
, et al.
·
Journal of Fluorine Chemistry
·
1
PDF
Multigram synthesis and physicochemical evaluation of (oxa)azaspiro[2. n ]alkane building blocks
2025
·
Sergiy Galavskyy
, Anton V. Chernykh
, et al.
·
Organic Chemistry Frontiers
·
1
PDF
Bicyclic 1,4‐Dioxepanes for Drug Discovery: Multigram Synthesis, Physicochemical, and Structural Characterization
2025
·
Andrii V. Bondarenko
, Yevhenii Kozyriev
, et al.
·
Chemistry - A European Journal
·
1
PDF
Functionalized Thietanes: an Overlooked Class of Building Blocks for Drug Discovery
2025
·
Oleksandr O. Stepaniuk
, Oleksii V. Gavrylenko
, et al.
·
ChemRxiv
·
1
PDF
Gram-scale synthesis and physicochemical properties of exo- and endo-5,5-difluorooctahydropentalen-2-amines
2025
·
Olena Voloshyna
, Bohdan Moroz
, et al.
·
Journal of Fluorine Chemistry
·
1
PDF
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Works count:
51
Citation count:
391
H-index:
9
I10-index:
9
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