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Author

Steven Lockhart

Observed institution: University of Alberta
ORCID: 0000-0001-5882-756X
Observed ORCID: 0000-0001-5882-756X
OpenAlex ID: A5103086740
The oxidation of fenamic acid NSAIDs by neutrophil myeloperoxidase produces toxic reactive metabolites that induce leukemic cell death
2023 · Newton H. Tran, Dinesh Babu, et al. · Redox Biochemistry and Chemistry · 9
Cysteine oxidation of a redox hub within complex I can facilitate electron transport chain supercomplex formation
2025 · Runtai Chen, Seyed Amirhossein Tabatabaei Dakhili, et al. · Journal of Biological Chemistry · 8
A chemoproteomic strategy for identifying protein covalent binding targets of clozapine: An approach for advancing clozapine toxicity research
2025 · Steven Lockhart, Yasser Tabana, et al. · Toxicology Letters · 4
The Interaction of Myeloperoxidase with the Industrial Contaminant 6-PPD: A Potential Pathway for Reactive Metabolites
2024 · Steven Lockhart, Dinesh Babu, et al. · Chemical Research in Toxicology · 4
Proteomic identification of protein radicals from myeloperoxidase-mediated mefenamic acid oxidation reveals a mechanism of NSAID-induced oxidative injury
2025 · Newton H. Tran, Steven Lockhart, et al. · Redox Biochemistry and Chemistry · 3
Sulforaphane treatment of HL-60 cells protects against clozapine toxicity and protein covalent binding: implications for clozapine-induced agranulocytosis
2025 · Md Harunur Rashid, Newton H. Tran, et al. · Chemico-Biological Interactions · 3
Edaravone as an antioxidant adjuvant to attenuate clozapine toxicity in vitro
2026 · Dinesh Babu, Thom H. Le, et al. · Toxicology Letters · 2
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Unraveling dimethylformamide-induced neutrophilic differentiation in HL-60 cells: A proteomic and functional comparison with dimethyl sulfoxide
2026 · Othman Eldalal, Yasser Tabana, et al. · PLoS ONE · 2
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Amino acid-supplemented polymeric nanogels enhance cryopreservation efficacies in single-cell suspensions and 2D monolayer cell cultures
2026 · Nauman Nazeer, Aayushi Vyas, et al. · RSC Applied Polymers · 1
Evaluating Protein Modification as a Shared Mechanism in Drug-Induced Agranulocytosis: In Vitro Studies with Five Chemically Diverse Drugs
2026 · Huan Liu, Newton H. Tran, et al. · Toxicology
Standardized human granulocyte isolation using Mono-Poly™ resolving medium: protocol development, validation, and comparison with Lymphoprep™
2026 · Othman Eldalal, Steven Lockhart, et al. · MethodsX
Quetiapine-induced myeloperoxidase-dependent neutrophil extracellular trap formation in in dimethylformamide-differentiated HL-60 cells
2026 · Othman Eldalal, Steven Lockhart, et al. · Free Radical Biology and Medicine
Abstract 2394 Oxidation of Cysteine Redox Switches Within Ndufs1 Can Promote Electron Transport Chain Supercomplex Assembly
2025 · Runtai Chen, Seyed Amirhossein Dakhili, et al. · Journal of Biological Chemistry
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The induction of quinone oxidoreductases NQO1 and NQO2 by clozapine: Potential implications for clozapine-induced agranulocytosis
2025 · Md Harunur Rashid, Dinesh Babu, et al. · Toxicology Letters
Works count: 14
Citation count: 36
H-index: 4
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