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Hiroki Kumamoto

Observed names: H Kumamoto, H. KUMAMOTO, H. Kumamoto, Hiroki Kumamoto,, Kumamoto, H., Kumamoto, Hiroki, 浩樹 熊本, 熊本, 浩樹, 熊本浩樹
Observed institutions: Kagoshima University, SHOWA Medical University, Université d'Orléans, Centre National de la Recherche Scientifique, Institut Pasteur, Nihon Pharmaceutical University, Hokkaido University, Kyoto University, Yale University, Institut Jacques Monod, Institut de Chimie Organique et Analytique, Chimie Biologique pour le Vivant, Université Pierre-et-Marie-Curie, Showa Pharmaceutical University
ORCID: 0000-0002-2191-4464
Observed ORCID: 0000-0002-2191-4464
OpenAlex ID: A5103255494
Radical-mediated stannylation of vinyl sulfones: access to novel 4′-modified neplanocin A analogues
2009 · Hiroki Kumamoto, Kazuki Deguchi, et al. · Tetrahedron · 56
A New Entry to 2-Substituted Purine Nucleosides Based on Lithiation-Mediated Stannyl Transfer of 6-Chloropurine Nucleosides
1997 · Keisuke Kato, Hiroyuki Hayakawa, et al. · The Journal of Organic Chemistry · 52
Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis
2008 · Hiroki Kumamoto, Dimitri Topalis, et al. · Tetrahedron · 49
Anti-Human Immunodeficiency Virus Type 1 Activity and Resistance Profile of 2′,3′-Didehydro-3′-Deoxy-4′-Ethynylthymidine In Vitro
2005 · Takao Nitanda, Xin Wang, et al. · Antimicrobial Agents and Chemotherapy · 47
Identification of a novel long-acting 4’-modified nucleoside reverse transcriptase inhibitor against HBV
2020 · Nobuyo Higashi-Kuwata, Sanae Hayashi, et al. · Journal of Hepatology · 31
Synthesis and Anti-Human Immunodeficiency Virus Activity of 4‘-Branched (±)-4‘-Thiostavudines
2006 · Hiroki Kumamoto, Takahito Nakai, et al. · Journal of Medicinal Chemistry · 31
Click Azide‐Alkyne Cycloaddition for the Synthesis of D ‐(–)‐1,4‐Disubstituted Triazolo‐Carbanucleosides
2009 · Julie Broggi, Hiroki Kumamoto, et al. · European Journal of Organic Chemistry · 29
Pyrolysis of UR-144, a synthetic cannabinoid, augments an affinity to human CB1 receptor and cannabimimetic effects in mice
2017 · Asuka Kaizaki-Mitsumoto, Kyoko Hataoka, et al. · The Journal of Toxicological Sciences · 27
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Lithiation-mediated CC silyl and stannyl migrations observed in 6-chloro-9-(β-d-ribofuranosyl)purine
1995 · Keisuke Kato, Hiroyuki Hayakawa, et al. · Tetrahedron Letters · 23
Sulfur Extrusion with Tin Radical: Synthesis of 4‘,5‘-Didehydro-5‘-deoxy-5‘-(tributylstannyl)adenosine, an Intermediate for Potential Inhibitors against S-Adenosyl Homocysteine Hydrolase
2003 · Hiroki Kumamoto, Sayoko Onuma, et al. · The Journal of Organic Chemistry · 22
Development of radioiodinated nucleoside analogs for imaging tissue proliferation: comparisons of six 5-iodonucleosides
2003 · Jun Toyohara, Akio Hayashi, et al. · Nuclear Medicine and Biology · 22
Synthesis of (±)-4'-Ethynyl and 4'-Cyano Carbocyclic Analogues of Stavudine (d4T)
2005 · Hiroki Kumamoto, Kazuhiro Haraguchi, et al. · Nucleosides Nucleotides & Nucleic Acids · 21
A versatile intermediate for the synthesis of 3′-substituted 2′,3′-didehydro-2′,3′-dideoxyadenosine (d4A): preparation of 3′-C-stannyl-d4A via radical-mediated desulfonylative stannylation
2002 · Sayoko Onuma, Hiroki Kumamoto, et al. · Tetrahedron · 21
First Evident Generation of Purin-2-yllithium: Lithiation of an 8-Silyl-Protected 6-Chloropurine Riboside as a Key Step for the Synthesis of 2-Carbon-Substituted Adenosines
1999 · Hiroki Kumamoto, Hiromichi Tanaka, et al. · The Journal of Organic Chemistry · 21
Nucleotide binding to human UMP‐CMP kinase using fluorescent derivatives − a screening based on affinity for the UMP‐CMP binding site
2007 · Dimitri Topalis, Hiroki Kumamoto, et al. · FEBS Journal · 18
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Pointer 4'-Ethynylstavudine (4'-Ed4T) Has Potent Anti-HIV-1 Activity with Reduced Toxicity and Shows a Unique Activity Profile against Drug-Resistant Mutants
2005 · Hiromichi Tanaka, Kazuhiro Haraguchi, et al. · Antiviral chemistry & chemotherapy · 18
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Diastereoselective Synthesis of 6″-(Z)- and 6″-(E)-Fluoro Analogues of Anti-hepatitis B Virus Agent Entecavir and Its Evaluation of the Activity and Toxicity Profile of the Diastereomers
2016 · Hiroki Kumamoto, Misato Fukano, et al. · The Journal of Organic Chemistry · 15
Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market
2015 · Asuka Kaizaki-Mitsumoto, Naoki Noguchi, et al. · Forensic Toxicology · 15
Simple Entry to 3‘-Substituted Analogues of Anti-HIV Agent Stavudine Based on an Anionic O → C Stannyl Migration
2002 · Hiroki Kumamoto, Hiromichi Tanaka · The Journal of Organic Chemistry · 14
An Intramolecular Anionic Migration of a Stannyl Group from the 6-Position of 1-(2-Deoxy- d - erythro -pent-1-enofuranosyl)uracil to the 2′-Position: Synthesis of 2′-Substituted 1′,2′-Unsaturated Uridines
2000 · Hiroki Kumamoto, Satoru Shindoh, et al. · Tetrahedron · 14
Synthesis of 2-Alkynylcordycepins and Evaluation of Their Vasodilating Activity
1998 · Hiroki Kumamoto, Hiroyuki Hayakawa, et al. · Nucleosides Nucleotides & Nucleic Acids · 14
Synthesis of the 5′‐Fluoro‐2′β‐methyl Analogues of Neplanocin
2011 · Hiroki Kumamoto, Marina Kobayashi, et al. · European Journal of Organic Chemistry · 13
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Nucleophilic Addition of Benzenethiol to 1‘,2‘-Unsaturated Nucleosides: 1‘-C-Phenylthio-2‘-deoxynucleosides as Anomeric Radical Precursors
2002 · Hiroki Kumamoto, Miki Murasaki, et al. · The Journal of Organic Chemistry · 13
Synthesis of 4′-substituted 2′-deoxy-4′-thiocytidines and its evaluation for antineoplastic and antiviral activities
2019 · Kazuhiro Haraguchi, Hiroki Kumamoto, et al. · Tetrahedron · 12
Synthesis of (±)-4′-ethynyl-5′,5′-difluoro-2′,3′-dehydro-3′-deoxy- carbocyclic thymidine: a difluoromethylidene analogue of promising anti-HIV agent Ed4T
2009 · Hiroki Kumamoto, Kazuhiro Haraguchi, et al. · Tetrahedron · 12
Works count: 100
Citation count: 757
H-index: 16
I10-index: 30
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