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Matthias Gerlach
Observed names:
Gerlach Matthias,
Gerlach, Matthias
Institution:
Aeterna Zentaris (Germany)
Observed institutions:
Goethe University Frankfurt,
Centre National de la Recherche Scientifique,
Technische Universität Darmstadt,
CancerCare Manitoba,
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI),
Aeterna Zentaris (Germany),
Nantes Université
show all 7
OpenAlex ID:
A5103421080
N-Benzoylated Phenoxazines and Phenothiazines: Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization
2011
·
Helge Prinz
, Behfar Chamasmani
, et al.
·
Journal of Medicinal Chemistry
·
65
Sulfonate Derivatives of Naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-Anthracenone as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization
2007
·
Anne Zuse
, Peter Schmidt
, et al.
·
Journal of Medicinal Chemistry
·
52
Metalated 2-Alkenylsulfoximines: Efficient Solutions for Asymmetric d3-Synthons
1996
·
Michael Reggelin
, Heinz Weinberger
, et al.
·
Journal of the American Chemical Society
·
36
Metallated 2-Alkenyl Sulfoximines in Asymmetric Synthesis: Regio- and Stereoselective Synthesis of Highly Substituted Oxabicyclic Ethers and Studies Towards the Total Syntheses of the Euglobals G1 and G2 and Arenaran A
1999
·
Michael Reggelin
, Matthias Gerlach
, et al.
·
European Journal of Organic Chemistry
·
35
10-(2-oxo-2-Phenylethylidene)-10H-anthracen-9-ones as Highly Active Antimicrotubule Agents: Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization
2009
·
Helge Prinz
, Peter Schmidt
, et al.
·
Journal of Medicinal Chemistry
·
27
9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as Novel Antimicrotubule AgentsSynthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization
2006
·
Anne Zuse
, Peter Schmidt
, et al.
·
Journal of Medicinal Chemistry
·
26
Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety
2010
·
Holger C. Nickel
, Peter Schmidt
, et al.
·
European Journal of Medicinal Chemistry
·
23
A Convenient Synthesis of Novel 2,8-Disubstituted Pyrido[3,4-b]pyrazines Possessing Biological Activity
2011
·
Pascal Marchand
, Maud Antoine
, et al.
·
Synthesis
·
22
Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents—synthesis, antiproliferative activity and inhibition of tubulin polymerization
2011
·
Helge Prinz
, Peter Schmidt
, et al.
·
Bioorganic & Medicinal Chemistry
·
18
Translational potential of the ghrelin receptor agonist macimorelin for seizure suppression in pharmacoresistant epilepsy
2021
·
An Buckinx
, Anouk Pierre
, et al.
·
European Journal of Neurology
·
12
PDF
Discovery of 7‐Aryl‐Substituted (1,5‐Naphthyridin‐4‐yl)ureas as Aurora Kinase Inhibitors
2013
·
Julien Defaux
, Maud Antoine
, et al.
·
ChemMedChem
·
12
Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells
2014
·
Julien Defaux
, Maud Antoine
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
9
Preparation of Novel 2,3,8-Trisubstituted Pyrido[3,4-b]pyrazines and Pyrido[2,3-b]pyrazines
2011
·
Pascal Marchand
, Maud Antoine
, et al.
·
Synthesis
·
7
Design and Synthesis of a Focused Library of Novel Aryl‐ and Heteroaryl‐Ketopiperazides
2004
·
Matthias Gerlach
, Eckhard Claus
, et al.
·
Archiv der Pharmazie
·
7
Efficient synthesis of novel disubstituted pyrido[3,4-b]pyrazines for the design of protein kinase inhibitors
2015
·
Maud Antoine
, Tilmann Schuster
, et al.
·
MedChemComm
·
5
Abstract 871: Dual inhibition of PI3K and Erk1/2 shows synergy and efficacy in human tumor cells, either by using drug combinations or novel dual PI3K/Erk inhibitors
2012
·
Irene Seipelt
, Matthias Gerlach
, et al.
·
Cancer Research
·
3
Abstract 5476: LHRH receptor targeting as mechanism of anti-tumor activity for cytotoxic conjugates of Disorazol Z with the LHRH receptor agonistic peptide D-Lys6-LHRH.
2013
·
Babette Aicher
, Tilmann Schuster
, et al.
·
Cancer Research
·
1
ChemInform Abstract: A Convenient Synthesis of Novel 2,8‐Disubstituted Pyrido[3,4‐b]pyrazines Possessing Biological Activity.
2012
·
Maud Antoine
, Matthias Gerlach
, et al.
·
ChemInform
·
1
ChemInform Abstract: Preparation of Novel 2,3,8‐Trisubstituted Pyrido[3,4‐b]pyrazines and Pyrido[2,3‐b]pyrazines.
2011
·
Maud Antoine
, Michael Czech
, et al.
·
ChemInform
·
1
Abstract 3563: A highly selective Erk1/2 Inhibitor with in-vivo anti tumor potency
2011
·
Irene Seipelt
, Eckhard Guenther
, et al.
·
Cancer Research
·
1
2-Hydroxy-4,6-dimethoxy-3-(3-methylbutanoyl)benzaldehyde
2007
·
Jan W. Bats
, Matthias Gerlach
, et al.
·
Acta Crystallographica Section C Crystal Structure Communications
·
1
4-Substituted-piperazin-1-yl-carbonyl-pyrazol derivatives: A new class of highly potent cytotoxic compounds with inhibitory effects on tubulin polymerization
2004
·
Silke Baasner
, Matthias Gerlach
, et al.
·
Cancer Research
·
1
Abstract 3711: Erk inhibition as a therapeutic option for the treatment of Raf- and Mek- inhibitor resistant tumors
2014
·
Irene Seipelt
, Peter Schmidt
, et al.
·
Cancer Research
New Insights Into the Pathogenesis of Type 1 Diabetes
2013
·
von Herrath
, Gerlach Matthias
·
2013 CIS Annual Meeting: Regulation & Dysregulation of Immunity April 25 - 28, 2013
Cytotoxic conjugates of Disorazol Z with the LHRH receptor agonistic peptide D-Lys(6)-LHRH as approach to targeted therapy of LHRH-R positive tumors
2013
·
Gerlach, Matthias
, Aicher, Babette
, et al.
·
GRO
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Works count:
30
Citation count:
365
H-index:
11
I10-index:
11
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