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Jiann-Shiun Lai

Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter
1992 · Masafumi Tanaka, Jiann-Shiun Lai, et al. · Cell · 217
Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer
2019 · Po-Kai Chuang, Michael Hsiao, et al. · Proceedings of the National Academy of Sciences · 62
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Structural basis for the antibody neutralization ofHerpes simplex virus
2013 · Cheng-Chung Lee, Li-Ling Lin, et al. · Acta Crystallographica Section D Biological Crystallography · 51
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Interdigitated Residues within a Small Region of VP16 Interact with Oct-1, HCF, and DNA
1997 · Jiann-Shiun Lai, Winship Herr · Molecular and Cellular Biology · 48
Simple SPION Incubation as an Efficient Intracellular Labeling Method for Tracking Neural Progenitor Cells Using MRI
2013 · Chiao-Chi V. Chen, Min-Chi Ku, et al. · PLoS ONE · 42
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In vitro V(D)J recombination: Signal joint formation
1996 · Patricia Cortes, Frances Weis-Garcia, et al. · Proceedings of the National Academy of Sciences · 38
Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate
2021 · Ming-Chen Yang, Chi-Sheng Shia, et al. · Molecular Cancer Therapeutics · 35
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Generation of Potent Anti-Vascular Endothelial Growth Factor Neutralizing Antibodies from Mouse Phage Display Library for Cancer Therapy
2016 · Yan-Da Lai, Yen-Yu Wu, et al. · International Journal of Molecular Sciences · 15
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Identification of a novel function of the clathrin-coated structure at the plasma membrane in facilitating GM-CSF receptor-mediated activation of JAK2
2012 · Ping-Hung Chen, Fan-Ching Chien, et al. · Cell Cycle · 12
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Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-TSCM cells using a Quantum pBac-based CAR-T engineering system
2024 · Peter S. Chang, Yi-Chun Chen, et al. · PLoS ONE · 10
Immunogenicity of a spike protein subunit-based COVID-19 vaccine with broad protection against various SARS-CoV-2 variants in animal studies
2023 · Ming-Chen Yang, Chun-Chung Wang, et al. · PLoS ONE · 8
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Abstract 544: Anti-tumor efficacy and potential mechanism of action of a novel therapeutic humanized anti-Globo H antibody, OBI-888
2019 · Yu-Chi Chen, Ming-Chen Yang, et al. · Cancer Research · 4
Abstract 4084: Globo H-targeted CAR T cell cancer immunotherapy
2023 · Jiann-Shiun Lai, Shiou-Ling Jian, et al. · Cancer Research · 3
Abstract 544: Anti-tumor efficacy and potential mechanism of action of a novel therapeutic humanized anti-Globo H antibody, OBI-888
2019 · Yu-Chi Chen, Ming-Chen Yang, et al. · Clinical Research (Excluding Clinical Trials) · 3
Abstract 2934: The role of Globo H in cancer cell survival
2020 · Tzer-Min Kuo, Yi-Chien Tsai, et al. · Cancer Research · 2
Novel TROP2-targeted CAR T cells with high specificity and sustained efficacy for solid tumors in animal models.
2024 · Chih-Chun Liu, Tzer-Min Kuo, et al. · Journal of Clinical Oncology · 1
Potential role and prognostic value of Globo-H in lung cancer.
2024 · Tzer-Min Kuo, Jiann-Shiun Lai, et al. · Journal of Clinical Oncology · 1
Abstract 4814: Specificity, biodistribution, tumor targeting, and pharmacokinetics of a novel humanized anti-Globo H antibody, OBI-888, for cancer immunotherapy
2019 · Yu-Chi Chen, Ming-Chen Yang, et al. · Experimental and Molecular Therapeutics · 1
Abstract 4814: Specificity, biodistribution, tumor targeting, and pharmacokinetics of a novel humanized anti-Globo H antibody, OBI-888, for cancer immunotherapy
2019 · Yu-Chi Chen, Ming-Chen Yang, et al. · Cancer Research · 1
Supplementary Figures and Tables from Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate
2023 · Ming-Chen Yang, Chi-Sheng Shia, et al.
Supplementary Materials and Methods from Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate
2023 · Ming-Chen Yang, Chi-Sheng Shia, et al.
Data from Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate
2023 · Ming-Chen Yang, Chi-Sheng Shia, et al.
Data from Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate
2023 · Ming-Chen Yang, Chi-Sheng Shia, et al.
Abstract 6111: OBI-3424, an AKR1C3-activated prodrug, exhibits in vivo synergistic anti-tumor effect in combination with pembrolizumab by induction of immunogenic cell death
2022 · Chun-Chung Wang, Wan-Fen Li, et al. · Cancer Research
Abstract 3176: Inhibitory activity of Globo-H and SSEA-4 on activated T-cells
2021 · Tzer-Min Kuo, Chin-Chan Lee, et al. · Cancer Research
Works count: 25
Citation count: 554
H-index: 10
I10-index: 10
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