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Qunsheng Ji

Preclinical Pharmacology of AZD5363, an Inhibitor of AKT: Pharmacodynamics, Antitumor Activity, and Correlation of Monotherapy Activity with Genetic Background
2012 · Barry R. Davies, Hannah Greenwood, et al. · Molecular Cancer Therapeutics · 492
Discovery of OSI-906: A Selective and Orally Efficacious Dual Inhibitor of the IGF-1 Receptor and Insulin Receptor
2009 · Mark J Mulvihill, Andrew Cooke, et al. · Future Medicinal Chemistry · 316
Phospholipase C-γ as a Signal-Transducing Element
1999 · Graham Carpenter, Qun-sheng Ji · Experimental Cell Research · 252
FGFR2 Gene Amplification in Gastric Cancer Predicts Sensitivity to the Selective FGFR Inhibitor AZD4547
2013 · Liang Xie, Xinying Su, et al. · Clinical Cancer Research · 244
Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors
2008 · Elizabeth Buck, Alexandra Eyzaguirre, et al. · Cancer Research · 213
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Polydactyly and ectopic ZPA formation in Alx-4 mutant mice
1997 · Shimian Qu, Kevin D. Niswender, et al. · Development · 196
Focal adhesion kinase promotes phospholipase C-γ1 activity
1999 · Xiaoe Zhang, Ansuman Chattopadhyay, et al. · Proceedings of the National Academy of Sciences · 194
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Translating the Therapeutic Potential of AZD4547 in FGFR1 -Amplified Non–Small Cell Lung Cancer through the Use of Patient-Derived Tumor Xenograft Models
2012 · Jingchuan Zhang, Lin Zhang, et al. · Clinical Cancer Research · 156
A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor–dependent tumor growth in vivo
2007 · Qun-sheng Ji, Mark J. Mulvihill, et al. · Molecular Cancer Therapeutics · 152
The diagnostic accuracy of pleural effusion and plasma samples versus tumour tissue for detection of EGFR mutation in patients with advanced non-small cell lung cancer: comparison of methodologies
2013 · Xiaoqing Liu, Yachao Lu, et al. · Journal of Clinical Pathology · 145
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Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization
2014 · Min Yang, Jingwei Liu, et al. · Molecular Cancer · 139
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Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer
2019 · Shuaishuai Teng, Yang Eric Li, et al. · Cell Research · 131
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The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors
2018 · Thijs J. Hagenbeek, Joshua D. Webster, et al. · Science Signaling · 89
Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: useful tools for preclinical studies of targeted therapies
2013 · Xu-chao Zhang, Jingchuan Zhang, et al. · Journal of Translational Medicine · 89
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Small‐molecule inhibition and activation‐loop trans‐phosphorylation of the IGF1 receptor
2008 · Jinhua Wu, Wanqing Li, et al. · The EMBO Journal · 83
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High T790M Detection Rate in TKI-Naive NSCLC with EGFR Sensitive Mutation: Truth or Artifact?
2013 · Xin Ye, Zhong-Zheng Zhu, et al. · Journal of Thoracic Oncology · 81
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Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development
2015 · Qingyang Gu, Bin Zhang, et al. · Oncotarget · 80
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The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere
2013 · Jing Li, Barry R Davies, et al. · Journal of Translational Medicine · 79
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Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors
2007 · Mark J. Mulvihill, Qun-Sheng Ji, et al. · Bioorganic & Medicinal Chemistry · 76
Whole genome gene copy number profiling of gastric cancer identifies PAK1 and KRAS gene amplification as therapy targets
2014 · Ziliang Qian, Guanshan Zhu, et al. · Genes Chromosomes and Cancer · 73
Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma
2015 · Hua Dong, Lan Zhang, et al. · PLoS ONE · 68
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Epidermal Growth Factor Signaling and Mitogenesis inPlcg1Null Mouse Embryonic Fibroblasts
1998 · Qun-sheng Ji, Sandra Ermini, et al. · Molecular Biology of the Cell · 68
Antitumor effects of regorafenib and sorafenib in preclinical models of hepatocellular carcinoma
2017 · Maria Kissel, Sandra Berndt, et al. · Oncotarget · 63
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A retrospective analysis of RET translocation, gene copy number gain and expression in NSCLC patients treated with vandetanib in four randomized Phase III studies
2015 · Adam Platt, John Morten, et al. · BMC Cancer · 60
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Phospholipase C-γ1 is required for cell survival in oxidative stress by protein kinase C
2002 · Xiao-Chun BAI, Fan DENG, et al. · Biochemical Journal · 59
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Works count: 124
Citation count: 4,215
H-index: 31
I10-index: 46
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