Get started
Author

Alok Ranjan Singh

A Macrophage-Dominant PI3K Isoform Controls Hypoxia-Induced HIF1α and HIF2α Stability and Tumor Growth, Angiogenesis, and Metastasis
2014 · Shweta Joshi, Alok R. Singh, et al. · Molecular Cancer Research · 130
Rac2 Controls Tumor Growth, Metastasis and M1-M2 Macrophage Differentiation In Vivo
2014 · Shweta Joshi, Alok R. Singh, et al. · PLoS ONE · 127
PDF
Dual-activity PI3K–BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis
2017 · Forest H. Andrews, Alok R. Singh, et al. · Proceedings of the National Academy of Sciences · 119
MDM2 Regulates Hypoxic Hypoxia-inducible Factor 1α Stability in an E3 Ligase, Proteasome, and PTEN-Phosphatidylinositol 3-Kinase-AKT-dependent Manner
2014 · Shweta Joshi, Alok R. Singh, et al. · Journal of Biological Chemistry · 96
PDF
DNA Binding and Topoisomerase II Inhibitory Activity of Water-Soluble Ruthenium(II) and Rhodium(III) Complexes
2007 · Sanjay Kumar Singh, Shweta Joshi, et al. · Inorganic Chemistry · 81
Single Agent and Synergistic Activity of the “First-in-Class” Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma
2016 · Alok R. Singh, Shweta Joshi, et al. · Molecular Cancer Therapeutics · 63
SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer
2019 · Shweta Joshi, Alok R. Singh, et al. · Molecular Cancer Therapeutics · 52
Macrophage Syk–PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk–PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression
2020 · Shweta Joshi, Kevin X. Liu, et al. · Molecular Cancer Therapeutics · 42
Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype
2017 · Shweta Joshi, Alok R. Singh, et al. · PLoS ONE · 33
PDF
Molecular cloning and characterization of Brugia malayi hexokinase
2008 · Alok Ranjan Singh, Shweta Joshi, et al. · Parasitology International · 33
Molecular cloning and characterization of Plasmodium falciparum transketolase
2008 · Shweta Joshi, Alok Ranjan Singh, et al. · Molecular and Biochemical Parasitology · 33
PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma
2016 · Alok R. Singh, Shweta Joshi, et al. · PLoS ONE · 31
PDF
Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
2016 · Anat Erdreich-Epstein, Alok R. Singh, et al. · Oncotarget · 28
PDF
Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma
2015 · Shweta Joshi, Alok R. Singh, et al. · Cancer Chemotherapy and Pharmacology · 25
Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in 12 V-Ha-Ras transgenic mouse glioma model
2014 · Alok R Singh, Shweta Joshi, et al. · Cancer Cell International · 21
PDF
A Novel Affinity Engineered Anti-CD47 Antibody With Improved Therapeutic Index That Preserves Erythrocytes and Normal Immune Cells
2022 · Youg R. Thaker, Ianne Rivera, et al. · Frontiers in Oncology · 19
PTEN and PI-3 kinase inhibitors control LPS signaling and the lymphoproliferative response in the CD19+ B cell compartment
2014 · Alok R. Singh, Susan K. Peirce, et al. · Experimental Cell Research · 17
Guanidine hydrochloride and urea-induced unfolding of Brugia malayi hexokinase
2009 · Alok Ranjan Singh, Shweta Joshi, et al. · European Biophysics Journal · 17
PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression
2013 · Carrie R. Muh, Shweta Joshi, et al. · Journal of Neuro-Oncology · 16
Purification and characterization of phosphoenolpyruvate carboxykinase fromRaillietina echinobothrida, a cestode parasite of the domestic fowl
2012 · B. DAS, V. TANDON, et al. · Parasitology · 14
Oxygenated chalcones and bischalcones as a new class of inhibitors of DNA topoisomerase II of malarial parasites
2007 · Shalini Srivastava, Shweta Joshi, et al. · Medicinal Chemistry Research · 11
Identification of potential P. falciparum transketolase inhibitors: pharmacophore design, in silico screening and docking studies
2010 · Shweta Joshi, Alok Ranjan Singh, et al. · Journal of Biophysical Chemistry · 10
PDF
A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis
2014 · Shweta Joshi, Alok Ranjan Singh, et al. · BMC Immunology · 7
PDF
Abstract A27: Dual PI3K/BRD4 (kinase/epigenetic) inhibitors for maximal MYC control in cancer therapeutics
2015 · Alok R. Singh, Shweta Joshi, et al. · Molecular Cancer Therapeutics · 3
Navigating the Edge-Intelligence Frontier: A Comparative Analysis of Quantization Strategies for Sub-1B Parameter Language Models
2026 · Ashwini Shivdas Shinde, Kanchan Digambar Patkar, et al. · International Conference on Innovation & Growth in Next-Gen Intelligent Technology & Engineering (IGNITE)
Works count: 43
Citation count: 1,028
H-index: 17
I10-index: 22
Year
Topic
Type