Author

Donogh P. O'Brien

Observed names: D O’Brien, D P O'Brien, D P O’Brien, D. O'Brien, D. P. O'Brien, D. P. O??Brien, D.P. O'BRIEN, D.P. O'Brien, DONOGH O'BRIEN, DP O'Brien, Donogh O'Brien, Donogh O’Brien, Donogh P O’Brien, Donogh Paul O'BRIEN, Donogh Paul O'Brien, O'Brien, Donogh

Observed institutions: Cleveland Clinic, Zoological Society of London, Emory University, Okayama University, Queen Mary University of London, Genentech, Sanford Burnham Prebys Medical Discovery Institute, The Royal Free Hospital, Hammersmith Hospital, Northwick Park Hospital, UNSW Sydney, University of Oxford, Medical Research Council, University of Edinburgh

OpenAlex ID: A5091154872

Structure of human factor VIII

1984 · Gordon A. Vehar, Bruce Keyt, et al. · Nature · 888

Crystal structure of the extracellular region of human tissue factor

1994 · K. Harlos, D. M. A. Martin, et al. · Nature · 228

Purification of human factor VIII:C and its characterization by Western blotting using monoclonal antibodies

1985 · Frances Rotblat, Donogh P. O'Brien, et al. · Biochemistry · 138

Purification and characterization of factor VII 304-Gln: a variant molecule with reduced activity isolated from a clinically unaffected male

1991 · DP O'Brien, KM Gale, et al. · Blood · 120

Purification of recombinant human tissue factor

1989 · Lisa R. Paborsky, Keri M. Tate, et al. · Biochemistry · 113

Cloning and expression of human tissue factor cDNA

1987 · Karen L. Fisher, Cornelia M. Gorman, et al. · Thrombosis Research · 98

Surface plasmon resonance studies of the interaction between factor VII and tissue factor. Demonstration of defective tissue factor binding in a variant FVII molecule (FVII-R79Q)

1994 · D. P. O'Brien, G. Kemball-Cook, et al. · Biochemistry · 67

Inactivation of factor VIII by factor IXa

1992 · Donogh Paul O'Brien, Daniel Johnson, et al. · Biochemistry · 50

Monoclonal antibodies to human procoagulant factor VIII.

1983 · F Rotblat, A H Goodall, et al. · PubMed · 50

Purification and characterization of factor VIII 1,689-Cys: a nonfunctional cofactor occurring in a patient with severe hemophilia A

1989 · DP O'Brien, EG Tuddenham · Blood · 36

Inhibition by Argatroban, a Specific Thrombin Inhibitor, of Platelet Activation by Fibrin Clot-associated Thrombin

1996 · Catherine Lunven, Christiane Gauffeny, et al. · Thrombosis and Haemostasis · 35

Purification and characterization of factor VIII 372-Cys: a hypofunctional cofactor from a patient with moderately severe hemophilia A

1990 · DP O'Brien, JK Pattinson, et al. · Blood · 34

High-level production of human blood coagulation factors VII and XI using a new mammalian expression vector

1994 · Geoffrey Kemball-Cook, Ian Garner, et al. · Gene · 31

The relationship between factor VII coagulant activity and factor XII activation induced in plasma by endogenous or exogenously added contact surface

1993 · K. A. Mitropoulos, B. E. A. Reeves, et al. · Blood Coagulation & Fibrinolysis · 31

Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis

2014 · Nicolas Delcourt, Celia Quevedo, et al. · Journal of Biological Chemistry · 30

Synthesis and characterization of wild-type and variant .gamma.-carboxyglutamic acid-containing domains of factor VII

1993 · David M. A. Martin, Donogh P. O'Brien, et al. · Biochemistry · 26

Preparation of factor IX deficient human plasma by immunoaffinity chromatography using a monoclonal antibody

1982 · AH Goodall, G Kemble, et al. · Blood · 23

Factor Vila and other Haemostatic Variables following Bone Marrow Transplantation

1994 · P Collins, A Roderick, et al. · Thrombosis and Haemostasis · 22

Human thrombopoietin structure–function relationships: identification of functionally important residues

1998 · Alexandre JAGERSCHMIDT, Valérie FLEURY, et al. · Biochemical Journal · 17

Factor VIIa and the extracellular domains of human tissue factor form a compact complex: A study by X‐ray and neutron solution scattering

1995 · Alun W. Ashton, Geoffrey Kemball-Cook, et al. · FEBS Letters · 16

Factor VIII-bypassing activity of bovine tissue factor using the canine hemophilic model.

1988 · D P O'Brien, A R Giles, et al. · Journal of Clinical Investigation · 15

Ecarin Clotting Time: a Predictive Coagulation Assay for the Antithrombotic Activity of Argatroban in the Rat

1998 · Catherine Lunven, Christine Girardot, et al. · Thrombosis and Haemostasis · 14

Factor VIII S373L: Mutation at P1’ Site Confers Thrombin Cleavage Resistance, Causing Mild Haemophilia A

1994 · D J D Johnson, S Pemberton, et al. · Thrombosis and Haemostasis · 14

Structural requirements for the interaction between tissue factor and factor VII: characterization of chymotrypsin-derived tissue factor polypeptides

1993 · D P O'Brien, J S Anderson, et al. · Biochemical Journal · 14

Crystallization and Preliminary X-ray Analysis of Human Tissue Factor Extracellular Domain

1993 · C.W.G. Boys, A. Miller, et al. · Journal of Molecular Biology · 12

Works count: 45

Citation count: 2,161

H-index: 18

I10-index: 27