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Shigehiro Asano

Rapid, Stable, Chemoselective Labeling of Thiols with Julia–Kocieński‐like Reagents: A Serum‐Stable Alternative to Maleimide‐Based Protein Conjugation
2013 · Narihiro Toda, Shigehiro Asano, et al. · Angewandte Chemie International Edition · 200
Crystal Structures and Structure–Activity Relationships of Imidazothiazole Derivatives as IDO1 Inhibitors
2014 · Shingo Tojo, Tetsuya Kohno, et al. · ACS Medicinal Chemistry Letters · 144
Improving the Serum Stability of Site-Specific Antibody Conjugates with Sulfone Linkers
2014 · James T. Patterson, Shigehiro Asano, et al. · Bioconjugate Chemistry · 90
Site‐Selective Labeling of a Lysine Residue in Human Serum Albumin
2014 · Shigehiro Asano, James T. Patterson, et al. · Angewandte Chemie International Edition · 84
Synthesis of pinnaic acid; Asymmetric construction of spirocyclic core
1999 · Hirokazu Arimoto, Shigehiro Asano, et al. · Tetrahedron Letters · 49
Rapid, Stable, Chemoselective Labeling of Thiols with Julia–Kocieński‐like Reagents: A Serum‐Stable Alternative to Maleimide‐Based Protein Conjugation
2013 · Narihiro Toda, Shigehiro Asano, et al. · Angewandte Chemie · 34
Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts
2014 · Manabu Watanabe, Mai Kasai, et al. · ACS Medicinal Chemistry Letters · 28
Suzuki–Miyaura cross-coupling reaction of aryl and heteroaryl pinacol boronates for the synthesis of 2-substituted pyrimidines
2011 · Shigehiro Asano, Seiji Kamioka, et al. · Tetrahedron · 21
Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation
2016 · James T. Patterson, Henry D. Wilson, et al. · Bioconjugate Chemistry · 20
Preparation and Activities of Macromolecule Conjugates of the CCR5 Antagonist Maraviroc
2013 · Shigehiro Asano, Julia Gavrilyuk, et al. · ACS Medicinal Chemistry Letters · 20
Identification of phosphodiesterase-1 and 5 dual inhibitors by a ligand-based virtual screening optimized for lead evolution
2005 · Kazuto Yamazaki, Naoto Kusunose, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Site‐Selective Labeling of a Lysine Residue in Human Serum Albumin
2014 · Shigehiro Asano, James T. Patterson, et al. · Angewandte Chemie · 15
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitors
2010 · Shigehiro Asano, Masafumi Komiya, et al. · Bioorganic & Medicinal Chemistry Letters · 13
Intellectual Property in the Field of Regenerative Medicine in Japan
2018 · Shigehiro Asano, Yoichi Nakanishi, et al. · Clinical Therapeutics · 12
Synthesis of Novel Benzo-Fused Heteroaryl Derivatives as Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitors
2013 · Masafumi Komiya, Shigehiro Asano, et al. · Chemical and Pharmaceutical Bulletin · 10
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Synthesis and structure based optimization of 2-(4-phenoxybenzoyl)-5-hydroxyindole as a novel CaMKII inhibitor
2012 · Masafumi Komiya, Shigehiro Asano, et al. · Bioorganic & Medicinal Chemistry · 10
Total synthesis of allixin; an anti-tumor promoter from garlic
1997 · Hirokazu Arimoto, Shigehiro Asano, et al. · Tetrahedron Letters · 10
Novel 1,4-diarylpiperidine-4-methylureas as anti-hyperlipidemic agents: Dual effectors on acyl-CoA:cholesterol O-acyltransferase and low-density lipoprotein receptor expression
2009 · Shigehiro Asano, Hitoshi Ban, et al. · Bioorganic & Medicinal Chemistry Letters · 6
A Novel Class of Antihyperlipidemic Agents with Low Density Lipoprotein Receptor Up-Regulation via the Adaptor Protein Autosomal Recessive Hypercholesterolemia
2010 · Shigehiro Asano, Hitoshi Ban, et al. · Journal of Medicinal Chemistry · 5
Structure and activity relationship of 2-(substituted benzoyl)-hydroxyindoles as novel CaMKII inhibitors
2011 · Masafumi Komiya, Shigehiro Asano, et al. · Bioorganic & Medicinal Chemistry Letters · 4
A Convenient One-Pot Preparation of N-Substituted 4-Phenylpiperidines
2008 · Hitoshi Ban, Shigehiro Asano · Heterocycles · 4
Development of an exon 27-skipping antisense oligonucleotide as a targeted therapy for refractory skin ulcers in Werner syndrome
2026 · Zhiqiu Man, Shigehiro Asano, et al. · Molecular Therapy — Nucleic Acids · 1
Synthesis and structure–activity relationships of N-(4-amino-2,6-diisopropylphenyl)-N’-(1,4-diarylpiperidine-4-yl)methylureas as anti-hyperlipidemic agents
2009 · Shigehiro Asano, Hitoshi Ban, et al. · Bioorganic & Medicinal Chemistry · 1
Ps-p14-7: Impacts of Constructing and Operating “karushioh” Certification System to Promote Delicious Low-salt Meals on the Japanese Low-salt Foods Market
2023 · Eiki Akagawa, Katsuhisa Tanaka, et al. · Journal of Hypertension
Ps-p14-3: Efforts of “s-1 Grand Prix”, a Delicious Less Salt Recipe Contest Aimed at Preventing Cardiovascular Diseases
2023 · Kaoru Sato, Sachie Watanabe, et al. · Journal of Hypertension
Works count: 29
Citation count: 797
H-index: 13
I10-index: 17
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