Author

Fabrizio Fiore

Observed name: F. Fiore

OpenAlex ID: A5106698187

Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

2010 · Frank Narjes, Benedetta Crescenzi, et al. · Journal of Medicinal Chemistry · 67

Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

2008 · Ester Muraglia, Olaf Kinzel, et al. · Journal of Medicinal Chemistry · 53

Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties

2009 · Olaf Kinzel, Laura Llauger-Bufi, et al. · Journal of Medicinal Chemistry · 46

Synthesis and evaluation of novel phosphoramidate prodrugs of 2′-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase

2009 · Monica Donghi, Barbara Attenni, et al. · Bioorganic & Medicinal Chemistry Letters · 32

Optimization of Thienopyrrole‐Based Finger‐Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase

2009 · Jose Ignacio Martin Hernando, Jesus Maria Ontoria, et al. · ChemMedChem · 31

Cyclic phosphoramidates as prodrugs of 2′-C-methylcytidine

2009 · Malte Meppen, Barbara Pacini, et al. · European Journal of Medicinal Chemistry · 31

Preclinical pharmacokinetics and metabolism of a potent non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase

2005 · C. Giuliano, F. Fiore, et al. · Xenobiotica · 22

Identification and SAR of novel pyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1)

2009 · Giovanna Pescatore, Danila Branca, et al. · Bioorganic & Medicinal Chemistry Letters · 21

Development of 2- butyl-N-methyl pyrimidones as potent inhibitors of HIV integrase

2008 · M. Emilia Di Francesco, Paola Pace, et al. · Bioorganic & Medicinal Chemistry Letters · 17

Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles

2009 · Steven Harper, Marco Ferrara, et al. · Journal of Medicinal Chemistry · 16

Development of 2-pyrrolidinyl-N-methyl pyrimidones as potent and orally bioavailable HIV integrase inhibitors

2010 · Marco Ferrara, Fabrizio Fiore, et al. · Bioorganic & Medicinal Chemistry Letters · 14

N-(4-Fluorobenzyl)-3-hydroxy-9,9-dimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrazino[1,2-a]pyrimidine-2-carboxamides a novel class of potent HIV-1 integrase inhibitors

2009 · Alessia Petrocchi, Philip Jones, et al. · Bioorganic & Medicinal Chemistry Letters · 12

Optimization of a series of potent and selective ketone histone deacetylase inhibitors

2008 · Giovanna Pescatore, Olaf Kinzel, et al. · Bioorganic & Medicinal Chemistry Letters · 12

Metabolism-related liabilities of a potent histone deacetylase (HDAC) inhibitor and relevance of the route of administration on its metabolic fate

2009 · M. Fonsi, F. Fiore, et al. · Xenobiotica · 7

a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

2011 · Frank Narjes, Benedetta Crescenzi, et al.

Works count: 15

Citation count: 381

H-index: 12

I10-index: 13