Author

Aijun Lu

Observed names: Ai-Jun Lu, Ai-jun LU, Lu, Aijun

Institution: Pharmaron (China)

Observed institutions: Chinese Academy of Sciences, Simcere Pharmaceutical (China), Institute of Process Engineering, Pharmaron (China)

OpenAlex ID: A5108239704

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

2016 · Matthew Volgraf, Benjamin D. Sellers, et al. · Journal of Medicinal Chemistry · 107

Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy

2021 · Jack A. Terrett, Huifen Chen, et al. · Journal of Medicinal Chemistry · 53

GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile

2016 · Elisia Villemure, Matthew Volgraf, et al. · ACS Medicinal Chemistry Letters · 44

Novel N-phenyl dichloroacetamide derivatives as anticancer reagents: Design, synthesis and biological evaluation

2010 · Yongchong Yang, Peihua Shang, et al. · European Journal of Medicinal Chemistry · 43

Discovery of a Potent (4R,5S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling

2018 · Huifen Chen, Matthew Volgraf, et al. · Journal of Medicinal Chemistry · 41

Novel hexacyclic camptothecin derivatives. Part 1: Synthesis and cytotoxicity of camptothecins with an A-ring fused 1,3-oxazine ring

2008 · Sheng Wang, Yuyan Li, et al. · Bioorganic & Medicinal Chemistry Letters · 41

Synthesis, in Vitro and in Vivo Biological Evaluation, Docking Studies, and Structure−Activity Relationship (SAR) Discussion of Dipeptidyl Boronic Acid Proteasome Inhibitors Composed of β-Amino Acids

2010 · Yongqiang Zhu, Xinrong Zhu, et al. · Journal of Medicinal Chemistry · 39

3D-QSAR studies of boron-containing dipeptides as proteasome inhibitors with CoMFA and CoMSIA methods

2008 · Yong-Qiang Zhu, Meng Lei, et al. · European Journal of Medicinal Chemistry · 33

3D-QSAR study of 20 (S)-camptothecin analogs

2007 · Ai-jun LU, Zhen-shan ZHANG, et al. · Acta Pharmacologica Sinica · 22

Design, synthesis and docking studies on benzamide derivatives as histone deacetylase inhibitors

2011 · Aijun Lu, Hongpeng Luo, et al. · Bioorganic & Medicinal Chemistry Letters · 18

Farnesyltransferase pharmacophore model derived from diverse classes of inhibitors

2006 · Aijun Lu, Jian Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 14

Pseudoreceptor Models and 3D-QSAR for Imidazobenzodiazepines at GABAA/BzR Subtypes αxβ3γ2 [x = 1−3, 5, and 6] via Flexible Atom Receptor Model

2004 · Aijun Lu, Jiaju Zhou · Journal of Chemical Information and Computer Sciences · 11

[Exploring relationship between traditional effects of traditional Chinese medicine and modern pharmacological activities by "co-effect compounds"].

2005 · Hai-Bo Liu, Ai-Jun Lu, et al. · PubMed · 1

New Diversity Criterion and Database Compression Method

2004 · B. Liu, Amazu LU, et al. · 1

A Traditional Chinese Medicine Plant-Compound Database and Its Application for Searching #

2004 · BioChem Press, Aijun Lu, et al. · 1

CCDC 1469512: Experimental Crystal Structure Determination

2016 · Volgraf, Matthew, Sellers, Benjamin D., et al. · The Cambridge Structural Database

Pseudoreceptor Models and 3D‐QSAR for Imidazobenzodiazepines at GABAA/BzR Subtypes αxβ3γ2 (x = 1—3, 5, and 6) via Flexible Atom Receptor Model.

2004 · Aijun Lu, Jiaju Zhou · ChemInform

Works count: 17

Citation count: 469

H-index: 11

I10-index: 12