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Antonella Loche

Observed name: Loche Antonella
OpenAlex ID: A5108264144
Synthesis of 2-Amino-5-sulfanyl-1,3,4-thiadiazole Derivatives and Evaluation of Their Antidepressant and Anxiolytic Activity
2001 · Francesca Clerici, Donato Pocar, et al. · Journal of Medicinal Chemistry · 241
γ‐Hydroxybutyrate modulation of glutamate levels in the hippocampus: an in vivo and in vitro study
2001 · Luca Ferraro, Sergio Tanganelli, et al. · Journal of Neurochemistry · 44
Neuroprotective effect of γ-hydroxybutyrate in transient global cerebral ischemia in the rat
2000 · Anna Valeria Vergoni, Alessandra Ottani, et al. · European Journal of Pharmacology · 38
A Phase I randomized clinical trial testing the safety, tolerability and preliminary pharmacokinetics of the mGluR5 negative allosteric modulator GET 73 following single and repeated doses in healthy volunteers
2017 · Carolina L. Haass-Koffler, Kimberly Goodyear, et al. · European Journal of Pharmaceutical Sciences · 26
Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73
2012 · Antonella Loche, Francesco Simonetti, et al. · Frontiers in Psychiatry · 22
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Gamma-hydroxybutyrate Reduces GABAA-mediated Inhibitory Postsynaptic Potentials in the CA1 Region of Hippocampus
2002 · M Cammalleri, Alfredo Brancucci, et al. · Neuropsychopharmacology · 20
The recognition and management of protracted alcohol withdrawal may improve and modulate the pharmacological treatment of alcohol use disorder
2020 · Fabio Caputo, Mauro Cibin, et al. · Journal of Psychopharmacology · 19
GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons
2015 · Maria C. Tomasini, Andrea C. Borelli, et al. · Alcohol and Alcoholism · 19
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Preference for palatable food is reduced by the gamma-hydroxybutyrate analogue GET73, in rats
2006 · Alessandra Ottani, Sheila Leone, et al. · Pharmacological Research · 17
Administration of the metabotropic glutamate receptor subtype 5 allosteric modulator GET 73 with alcohol: A translational study in rats and humans
2018 · Carolina L Haass-Koffler, Kimberly Goodyear, et al. · Journal of Psychopharmacology · 13
An inpatient human laboratory study assessing the safety and tolerability, pharmacokinetics, and biobehavioral effect of GET 73 when co-administered with alcohol in individuals with alcohol use disorder
2021 · Carolina L. Haass-Koffler, Roberta Perciballi, et al. · Psychopharmacology · 10
Dataset for Phase I randomized clinical trial for safety and tolerability of GET 73 in single and repeated ascending doses including preliminary pharmacokinetic parameters
2017 · Carolina L. Haass-Koffler, Kimberly Goodyear, et al. · Data in Brief · 9
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GET73 increases rat extracellular hippocampal CA1 GABA levels through a possible involvement of local mGlu5 receptor
2013 · Sarah Beggiato, William Thomas O'Connor, et al. · Synapse · 9
GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR5
2011 · Ferraro Luca, Beggiato Sarah, et al. · Pharmacological Reports · 9
In Vitro Functional Characterization of GET73 as Possible Negative Allosteric Modulator of Metabotropic Glutamate Receptor 5
2018 · Sarah Beggiato, Andrea C. Borelli, et al. · Frontiers in Pharmacology · 8
Reduction of Blood Ethanol Levels by the Gamma-Hydroxybutyric Acid Receptor Antagonist, NCS-382
1999 · Giancarlo Colombo, Roberta Agabio, et al. · Alcohol · 2
GET73 modulates lipopolysaccharide- and ethanol-induced increase in cytokine/chemokine levels in primary cultures of microglia of rat cerebral cortex
2024 · Maria C. Tomasini, Antonella Loche, et al. · Pharmacological Reports
ChemInform Abstract: Synthesis of 2‐Amino‐5‐sulfanyl‐1,3,4‐thiadiazole Derivatives and Evaluation of Their Antidepressant and Anxiolytic Activity.
2001 · Francesca Clerici, Donato Pocar, et al. · ChemInform
Works count: 20
Citation count: 506
H-index: 10
I10-index: 11
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