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Kazuo Sekiguchi
Observed name:
KAZUO SEKIGUCHI
Institution:
J-Pharma Co., Ltd. (Japan)
Observed institutions:
Otsuka (Japan),
Osaka Science Museum,
J-Pharma Co., Ltd. (Japan),
Massachusetts Institute of Technology,
Kobe University
OpenAlex ID:
A5108401014
Tyk2 Plays a Restricted Role in IFNα Signaling, Although It Is Required for IL-12-Mediated T Cell Function
2000
·
Kazuya Shimoda
, Kouji Kato
, et al.
·
Immunity
·
322
PDF
Expression and Properties of Two Types of Protein Kinase C: Alternative Splicing from a Single Gene
1987
·
Yoshitaka Ono
, Ushio Kikkawa
, et al.
·
Science
·
311
Three distinct forms of rat brain protein kinase C: Differential response to unsaturated fatty acids
1987
·
Kazuo Sekiguchi
, Masanori Tsukuda
, et al.
·
Biochemical and Biophysical Research Communications
·
235
Mode of Activation and Kinetic Properties of Three Distinct Forms of Protein Kinase C from Rat Brain1
1988
·
Kazuo Sekiguchi
, Masanori Tsukuda
, et al.
·
The Journal of Biochemistry
·
223
Identification of the structures of multiple subspecies of protein kinase C expressed in rat brain
1987
·
Ushio Kikkawa
, Yoshitaka Ono
, et al.
·
FEBS Letters
·
197
Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites
1989
·
Mark S. Shearman
, Zvi Naor
, et al.
·
FEBS Letters
·
184
The common structure and activities of four subspecies of rat brain protein kinase C family
1987
·
Ushio Kikkawa
, Kouji Ogita
, et al.
·
FEBS Letters
·
126
Further studies on the specificity of diacylglycerol for protein kinase C activation
1987
·
Go Masayoshi
, Kazuo Sekiguchi
, et al.
·
Biochemical and Biophysical Research Communications
·
112
Novel Thiazole Derivatives as Inhibitors of Superoxide Production by Human Neutrophils: Synthesis and Structure-Activity Relationships
1995
·
Masatoshi Chihiro
, Hisashi Nagamoto
, et al.
·
Journal of Medicinal Chemistry
·
85
Phosphorylation of the EGF receptor from A431 epidermoid carcinoma cells by three distinct types of protein kinase C
1987
·
Motoharu Ido
, Kazuo Sekiguchi
, et al.
·
FEBS Letters
·
72
PDF
Stereospecificity of diacylglycerol for stimulus-response coupling in platelets
1986
·
Hideaki Nomura
, Katsuhiko Ase
, et al.
·
Biochemical and Biophysical Research Communications
·
58
Activation of a brain‐specific protein kinase C subspecies in the presence of phosphatidylethanol
1988
·
Yoshinori Asaoka
, Ushio Kikkawa
, et al.
·
FEBS Letters
·
57
PDF
Properties of protein kinase c subspecies in human platelets
1988
·
Masanori Tsukuda
, Yoshinori Asaoka
, et al.
·
Biochemical and Biophysical Research Communications
·
52
Characterization of protein kinase C from normal and transformed cultured murine fibroblasts
1987
·
Patricia G. McCaffrey
, Marsha R. Rosner
, et al.
·
Biochemical and Biophysical Research Communications
·
38
Characterization of a novel nonpeptide vasopressin V2‐agonist, OPC‐51803, in cells transfected human vasopressin receptor subtypes
2000
·
Shigeki Nakamura
, Yoshitaka Yamamura
, et al.
·
British Journal of Pharmacology
·
32
PDF
OPC-18790, a quinolinone-derivative positive inotropic agent, inhibits potassium currents in guinea-pig ventricular myocytes.
1994
·
Hiromichi Takase
, Toyoki Mori
, et al.
·
The Japanese Journal of Pharmacology
·
6
PDF
Hepatotoxicity Reduction Profiles of Antisense Oligonucleotides Containing Amido-Bridged Nucleic Acid and 2′-O,4′-C-Spirocyclopropylene Bridged Nucleic Acid
2025
·
Takaaki Kawanobe
, Shinya Asano
, et al.
·
Nucleic Acid Therapeutics
·
5
PDF
Molecular heterogeneity and differential expression of multiple protein kinase C subspecies in central nervous tissue
1988
·
MARK S. SHEARMAN
, KATSUHIKO ASE
, et al.
·
Biochemical Society Transactions
·
4
Clinical and LAT1 Biomarker Correlates of Clinical Benefit from Nanvuranlat (JPH203) in Advanced Biliary Tract Cancer: A Post Hoc Analysis
2026
·
Eric K. Rowinsky
, Ghassan K. Abou-Alfa
, et al.
·
Cancers
·
1
Long-lasting Inhibition of L-type Amino Acid Transporter 1 by Nanvuranlat is Associated with Prolonged Cellular Retention Counteracted by Cancer-type OATP1B3 in Cholangiocarcinoma Cells
2026
·
Kiyoshi Oka
, Yusuke Masuo
, et al.
·
Pharmaceutical Research
EXTH-94. Can the tumor microenvironment attenuate drug efficacy? Potential vulnerabilities of LAT1 inhibitors
2025
·
Yuta Suzuki
, Cecile Riviere-Cazaux
, et al.
·
Neuro-Oncology
PDF
Characterization of long-lasting inhibition of amino acid transporter LAT1 by nanvuranlat (JPH203) in cholangiocellular carcinoma
2025
·
Kiyoshi Oka
, Yusuke Masuo
, et al.
·
Drug Metabolism and Pharmacokinetics
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Works count:
22
Citation count:
2,120
H-index:
15
I10-index:
15
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