Author

Garry J. Douglas

Observed names: G Douglas, G J Douglas, G. Douglas, G. J. Douglas, G.J Douglas, G.J. Douglas, Garry Douglas, Garry J Douglas

Institution: AstraZeneca (United Kingdom)

Observed institutions: University of Siena, AstraZeneca (United Kingdom), University of London, St Bartholomew's Hospital, Beth Israel Deaconess Medical Center, Harvard University, Queen Mary University of London, The University of Western Australia, King's College London, Pfizer (United Kingdom), King's College School, Northwick Park Institute for Medical Research, William Harvey Research Institute, Polyphor (Switzerland), University of Bath

OpenAlex ID: A5108466464

CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer

2015 · Jingyu Xiang, Michelle A. Hurchla, et al. · Molecular Cancer Therapeutics · 64

RSD931, a novel anti‐tussive agent acting on airway sensory nerves

2003 · J J Adcock, G J Douglas, et al. · British Journal of Pharmacology · 59

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A comparison of chromosomal aberrations induced by in vivo radiotherapy in human sperm and lymphocytes

1989 · R.H. Martin, A. Rademaker, et al. · Mutation Research Letters · 52

Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers—results of a dose escalation trial

2017 · Darja Karpova, Susanne Bräuninger, et al. · Journal of Translational Medicine · 49

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Anti-inflammatory modulation of chronic airway inflammation in the murine house dust mite model

2008 · Kristina Ulrich, Jennifer S. Hincks, et al. · Pulmonary Pharmacology & Therapeutics · 46

Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma

2014 · Amy Barone, Rajarshi Sengupta, et al. · Oncotarget · 43

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Platelet Accumulation Induced by Bacterial Endotoxin in Rats

1996 · Hidekazu Itoh, Carla Cicala, et al. · Thrombosis Research · 43

The translational challenge in the development of new and effective therapies for endometriosis: a review of confidence from published preclinical efficacy studies

2011 · Nick Pullen, Claire L. Birch, et al. · Human Reproduction Update · 41

Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti–Vascular Endothelial Growth Factor Therapy–Induced Glioma Dissemination

2017 · Jean-Pierre Gagner, Yasmeen Sarfraz, et al. · American Journal Of Pathology · 40

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POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALL

2015 · Edward Allan R. Sison, Daniel Magoon, et al. · Oncotarget · 39

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Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma

2019 · Kiyoshi Itagaki, Elzbieta Kaczmarek, et al. · Critical Care Medicine · 37

A novel animal model for investigating persistent airway hyperresponsiveness

1993 · Eleanor M. Minshall, Maggie M. Riccio, et al. · Journal of Pharmacological and Toxicological Methods · 37

A study on rat platelet responsiveness following intravenous endotoxin administration

1996 · Carla Cicala, Claudia Santacroce, et al. · Life Sciences · 22

The effect of 15‐HPETE on airway responsiveness and pulmonary cell recruitment in rabbits

1997 · M. M. Riccio, T. Matsumoto, et al. · British Journal of Pharmacology · 16

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Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation

2015 · François Daubeuf, Françoise Jung, et al. · Respiratory Research · 15

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Airway responsiveness in an allergic rabbit model

2011 · S.D. Keir, D. Spina, et al. · Journal of Pharmacological and Toxicological Methods · 14

A prospective serial study of the effects of radiotherapy on semen parameters, and hamster egg penetration rates.

1985 · R H Martin, A Rademaker, et al. · PubMed · 11

Relationship of Airway Responsiveness with Airway Morphometry in Normal and Immunized Rabbits

2001 · F.E. Woisin, C.M. Herd, et al. · Pulmonary Pharmacology & Therapeutics · 9

Direct Airway Instillation of Neutrophils Overcomes Chemotactic Deficits Induced by Injury

2020 · Quanzhi Zhang, Woon Yong Kwon, et al. · Shock · 8

Antigen-induced Bronchial Hyperresponsiveness in the Rabbit is not Dependent on M2-receptor Dysfunction

1999 · H.J Patel, G.J Douglas, et al. · Pulmonary Pharmacology & Therapeutics · 6

Preclinical characterization of AZD1163, a first-in-class anti-PAD2/4 bispecific antibody for the treatment of rheumatoid arthritis

2026 · Gary P. Sims, Lacie Scaletta, et al. · mAbs · 5

POL7085 or anti-CCL28 treatment inhibits development of post-paramyxoviral airway disease

2017 · Becky J. Buelow, Michelle Rohlfing, et al. · Immunity Inflammation and Disease · 4

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Potent Stem Cell Mobilization with the Novel CXCR4 Antagonist POL6326 - Results of a Phase IIa Dose Escalation Study in Comparison to G-CSF

2015 · Darja Karpova, Susanne Brauninger, et al. · Blood · 4

Peptide 204–212 of lipocortin 5 inhibits the generation of a prostacyclin-like factor from rat aorta preparations in vitro

1992 · G.J. Douglas, R.J. Flower, et al. · Prostaglandins · 4

Op0110 Azd1163 - First-in-class Anti-pad2/4 Bi-specific Antibody to Inhibit Autoantigen Formation in Rheumatoid Arthritis

2024 · D.A. Sims, J. Andrews, et al. · Annals of the Rheumatic Diseases · 3

Works count: 52

Citation count: 681

H-index: 15

I10-index: 17