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Andrew C. Good

Molecular Shape and Medicinal Chemistry: A Perspective
2010 · Anthony Nicholls, Georgia B. McGaughey, et al. · Journal of Medicinal Chemistry · 329
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Molecular docking towards drug discovery
1996 · Daniel A. Gschwend, Andrew C. Good, et al. · Journal of Molecular Recognition · 306
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Identification of ( R )- N -((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1 H -indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas
2016 · Rishi G. Vaswani, Victor S. Gehling, et al. · Journal of Medicinal Chemistry · 231
Optimization of CAMD techniques 3. Virtual screening enrichment studies: a help or hindrance in tool selection?
2008 · Andrew C. Good, Tudor I. Oprea · Journal of Computer-Aided Molecular Design · 186
Structure-activity relationships from molecular similarity matrices
1993 · Andrew C. Good, Sung Sau So, et al. · Journal of Medicinal Chemistry · 162
Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains
2016 · Terry D. Crawford, Vickie Tsui, et al. · Journal of Medicinal Chemistry · 118
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The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
2014 · Paul M. Scola, Li-Qiang Sun, et al. · Journal of Medicinal Chemistry · 118
An Empirical Process for the Design of High-Throughput Screening Deck Filters
2006 · Bradley C. Pearce, Michael J. Sofia, et al. · Journal of Chemical Information and Modeling · 101
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods
1993 · Andrew C. Good, Stephen J. Peterson, et al. · Journal of Medicinal Chemistry · 93
Ranking poses in structure-based lead discovery and optimization: current trends in scoring function development.
2007 · Ramkumar Rajamani, Andrew C Good · PubMed · 82
New Methodology for Profiling Combinatorial Libraries and Screening Sets: Cleaning Up the Design Process with HARPick
1997 · Andrew C. Good, Richard A. Lewis · Journal of Medicinal Chemistry · 80
Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
2014 · Paul M. Scola, Alan Xiangdong Wang, et al. · Journal of Medicinal Chemistry · 76
Discovery, design, and synthesis of indole-based EZH2 inhibitors
2015 · Victor S. Gehling, Rishi G. Vaswani, et al. · Bioorganic & Medicinal Chemistry Letters · 68
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors
2011 · Yibin Xiang, Bradford Hirth, et al. · Bioorganic & Medicinal Chemistry Letters · 66
Measuring CAMD technique performance: A virtual screening case study in the design of validation experiments
2004 · Andrew C. Good, Mark A. Hermsmeier, et al. · Journal of Computer-Aided Molecular Design · 66
New molecular shape descriptors: Application in database screening
1995 · Andrew C. Good, Todd J. A. Ewing, et al. · Journal of Computer-Aided Molecular Design · 63
Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins
2018 · Aline D. de Araujo, Junxian Lim, et al. · Journal of Medicinal Chemistry · 61
Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development
2024 · Binh T. Vu, Romyr Dominique, et al. · ACS Medicinal Chemistry Letters · 58
Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen–Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design
2021 · Scott J. Eron, Hongwei Huang, et al. · ACS Chemical Biology · 57
High-throughput and virtual screening: core lead discovery technologies move towards integration
2000 · Andrew C. Good, Stanley R. Krystek, et al. · Drug Discovery Today · 51
Three‐Dimensional Structure Database Searches
1996 · Andrew C. Good, Jonathan S. Mason · Reviews in computational chemistry · 51
Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis
2012 · Samuel W. Gerritz, Weixu Zhai, et al. · Journal of Medicinal Chemistry · 48
Analysis and optimization of structure-based virtual screening protocols
2003 · Andrew C. Good, Daniel L. Cheney, et al. · Journal of Molecular Graphics and Modelling · 47
Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor
2018 · Barbara Zheng, Stanley V. D’Andrea, et al. · ACS Medicinal Chemistry Letters · 44
Abstract ND09: The discovery and characterization of CFT8634: A potent and selective degrader of BRD9 for the treatment of SMARCB1-perturbed cancers
2022 · Katrina L. Jackson, Roman V. Agafonov, et al. · Cancer Research · 40
Works count: 79
Citation count: 3,312
H-index: 29
I10-index: 54
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