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Simon Yuji Zhou
Observed names:
Simon Y. Zhou,
Simon Zhou
Institution:
Aurinia (Canada)
Observed institutions:
Pfizer (United States),
University of California, Santa Cruz,
University of Michigan,
Bristol-Myers Squibb (United States),
Aurinia (Canada),
Daiichi Sankyo (United States),
Celgene (United States)
show all 7
ORCID:
0000-0003-4688-3307
Observed ORCID:
0000-0003-4688-3307
OpenAlex ID:
A5109036817
Why 90% of clinical drug development fails and how to improve it?
2022
·
Duxin Sun
, Wei Gao
, et al.
·
Acta Pharmaceutica Sinica B
·
1,970
PDF
What Went Wrong with Anticancer Nanomedicine Design and How to Make It Right
2020
·
Duxin Sun
, Simon Zhou
, et al.
·
ACS Nano
·
277
Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma
2010
·
Gail M. Gauvreau
, Louis-Philippe Boulet
, et al.
·
American Journal of Respiratory and Critical Care Medicine
·
233
Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation
2012
·
Jeanne Mendell
, Helen Kastrissios
, et al.
·
Thrombosis and Haemostasis
·
150
Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tumor penetration
2015
·
Nianhang Chen
, Carrie Brachmann
, et al.
·
Cancer Chemotherapy and Pharmacology
·
130
PDF
Pharmacokinetics and pharmacodynamics of nab ‐paclitaxel in patients with solid tumors: Disposition kinetics and pharmacology distinct from solvent‐based paclitaxel
2014
·
Nianhang Chen
, Yan Li
, et al.
·
The Journal of Clinical Pharmacology
·
123
PDF
Clinical Pharmacokinetics and Pharmacodynamics of Lenalidomide
2016
·
Nianhang Chen
, Simon Zhou
, et al.
·
Clinical Pharmacokinetics
·
90
PDF
Distinct biodistribution of doxorubicin and the altered dispositions mediated by different liposomal formulations
2017
·
Ruijuan Luo
, Yan Li
, et al.
·
International Journal of Pharmaceutics
·
71
Reappraisal of anticancer nanomedicine design criteria in three types of preclinical cancer models for better clinical translation
2021
·
Xin Luan
, Hebao Yuan
, et al.
·
Biomaterials
·
70
IL-13 Antibodies Influence IL-13 Clearance in Humans by Modulating Scavenger Activity of IL-13Rα2
2011
·
Marion T Kasaian
, Donald Raible
, et al.
·
The Journal of Immunology
·
67
Meal Composition Effects on the Oral Bioavailability of Indinavir in HIV-Infected Patients
1999
·
Peggy L. Carver
, David Fleisher
, et al.
·
Pharmaceutical Research
·
61
Pharmacologic Sensitivity of Paclitaxel to Its Delivery Vehicles Drives Distinct Clinical Outcomes of Paclitaxel Formulations
2015
·
Yan Li
, Nianhang Chen
, et al.
·
Molecular Pharmaceutics
·
47
Population pharmacokinetics of pomalidomide
2015
·
Yan Li
, Yejun Xu
, et al.
·
The Journal of Clinical Pharmacology
·
45
PDF
Pharmacokinetic Disposition Difference Between Cyclosporine and Voclosporin Drives Their Distinct Efficacy and Safety Profiles in Clinical Studies
2020
·
Yan Li
, Maria Palmisano
, et al.
·
Clinical Pharmacology Advances and Applications
·
43
PDF
The pharmacokinetic effect of coadministration of apremilast and methotrexate in individuals with rheumatoid arthritis and psoriatic arthritis
2014
·
Yong Liu
, Simon Zhou
, et al.
·
Clinical Pharmacology in Drug Development
·
40
PDF
Reduced Systemic Availability of an Antiarrhythmic Drug, Bidisomide, with Meal Co-administration: Relationship with Region-Dependent Intestinal Absorption
1998
·
Li-Heng Pao
, Simon Yuji Zhou
, et al.
·
Pharmaceutical Research
·
38
Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model
2005
·
Filippos Kesisoglou
, Simon Yuji Zhou
, et al.
·
Pharmaceutical Research
·
37
PDF
The impact of co‐administration of ketoconazole and rifampicin on the pharmacokinetics of apremilast in healthy volunteers
2014
·
Yong Liu
, Simon Zhou
, et al.
·
British Journal of Clinical Pharmacology
·
34
PDF
Slow drug delivery decreased total body clearance and altered bioavailability of immediate‐ and controlled‐release oxycodone formulations
2016
·
Yan Li
, Duxin Sun
, et al.
·
Pharmacology Research & Perspectives
·
33
PDF
No clinically significant drug interactions between lenalidomide and P-glycoprotein substrates and inhibitors: results from controlled phase I studies in healthy volunteers
2014
·
Nianhang. Chen
, Daniel Weiss
, et al.
·
Cancer Chemotherapy and Pharmacology
·
32
PDF
Regulation of Paracellular Absorption of Cimetidine and 5-Aminosalicylate in Rat Intestine
1999
·
Simon Yuji Zhou
, Nusara Piyapolrungroj
, et al.
·
Pharmaceutical Research
·
32
Population Pharmacokinetics of an Anti-PD-L1 Antibody, Durvalumab in Patients with Hematologic Malignancies
2019
·
Ken Ogasawara
, Kathryn Newhall
, et al.
·
Clinical Pharmacokinetics
·
31
PDF
Population pharmacokinetics of fedratinib in patients with myelofibrosis, polycythemia vera, and essential thrombocythemia
2019
·
Ken Ogasawara
, Simon Zhou
, et al.
·
Cancer Chemotherapy and Pharmacology
·
29
PDF
Structure‒tissue exposure/selectivity relationship (STR) correlates with clinical efficacy/safety
2022
·
Wei Gao
, Hongxiang Hu
, et al.
·
Acta Pharmaceutica Sinica B
·
26
PDF
Integrated Population Pharmacokinetics of Etanercept in Healthy Subjects and in Patients With Rheumatoid Arthritis Ankylosing Spondylitis
2010
·
Simon Y. Zhou
, Cathye Shu
, et al.
·
The Journal of Clinical Pharmacology
·
26
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Works count:
92
Citation count:
4,194
H-index:
25
I10-index:
45
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