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David E. Lenz
Observed names:
D E Lenz,
D LENZ,
D. E. LENZ,
D. E. Lenz,
D. Lenz,
D.E. Lenz,
David E Lenz,
David Lenz,
Lenz, David E.
show all 9
Institution:
United States Army
Observed institutions:
Boston University,
United States Department of the Army,
Hebrew University of Jerusalem,
University of California San Diego,
United States Army,
University of Arizona College of Medicine- Phoenix,
Arizona State University,
Walter Reed Army Institute of Research
show all 8
OpenAlex ID:
A5109074975
Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning
2007
·
Yue-Jin Huang
, Yue Huang
, et al.
·
Proceedings of the National Academy of Sciences
·
214
PDF
Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: A mini review
2006
·
David E. Lenz
, David Yeung
, et al.
·
Toxicology
·
203
Protection by butyrylcholinesterase against organophosphorus poisoning in nonhuman primates.
1991
·
C A Broomfield
, D M Maxwell
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
188
The effects of blood flow and detoxification on in vivo cholinesterase inhibition by soman in rats
1987
·
Donald M. Maxwell
, David E. Lenz
, et al.
·
Toxicology and Applied Pharmacology
·
120
Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys
2005
·
David E. Lenz
, Donald M. Maxwell
, et al.
·
Chemico-Biological Interactions
·
118
(07) In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia™) as a potential nerve agent bioscavenger
2005
·
D.M. Cerasoli
, E.M. Griffiths
, et al.
·
Chemico-Biological Interactions
·
88
Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model
2004
·
David T. Yeung
, Denis Josse
, et al.
·
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
·
85
Bioscavenger for Protection From Toxicity of Organophosphorus Compounds
2006
·
Ashima Saxena
, Wei Sun
, et al.
·
Journal of Molecular Neuroscience
·
82
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents
2010
·
Brian C. Geyer
, Latha Kannan
, et al.
·
Proceedings of the National Academy of Sciences
·
81
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters
2008
·
Patrick Masson
, Florian Nachon
, et al.
·
Chemico-Biological Interactions
·
81
Analysis of active‐site amino‐acid residues of human serum paraoxonase using competitive substrates
2005
·
David T. Yeung
, David E. Lenz
, et al.
·
FEBS Journal
·
62
Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman
2005
·
Richard K. Gordon
, Julian R. Haigh
, et al.
·
Chemico-Biological Interactions
·
61
Substantially improved pharmacokinetics of recombinant human butyrylcholinesterase by fusion to human serum albumin
2008
·
Yue-Jin Huang
, Paul M Lundy
, et al.
·
BMC Biotechnology
·
60
PDF
Effect of carboxylesterase inhibition on carbamate protection against soman toxicity.
1988
·
D M Maxwell
, K M Brecht
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
60
Partial characterization of an enzyme that hydrolyzes sarin, soman, tabun, and diisopropyl phosphorofluoridate (DFP)
1989
·
James S. Little
, Clarence A. Broomfield
, et al.
·
Biochemical Pharmacology
·
57
Organophosphate skin decontamination using immobilized enzymes
1999
·
Richard K Gordon
, Shawn R Feaster
, et al.
·
Chemico-Biological Interactions
·
56
Detection and quantification of the organophosphate insecticide paraoxon by competitive inhibition enzyme immunoassay
1982
·
Kenneth W. Hunter
, David E. Lenz
·
Life Sciences
·
48
Dramatic Differences in Organophosphorus Hydrolase Activity between Human and Chimeric Recombinant Mammalian Paraoxonase-1 Enzymes
2009
·
Tamara C. Otto
, Christina K. Harsch
, et al.
·
Biochemistry
·
47
The Role of Glutamate-199 in the Aging of Cholinesterase
1993
·
A. Saxena
, B.P. Doctor
, et al.
·
Biochemical and Biophysical Research Communications
·
46
A pharmacodynamic model for soman in the rat
1988
·
Donald M. Maxwell
, Constantine P. Vlahacos
, et al.
·
Toxicology Letters
·
46
Direct detection of stereospecific soman hydrolysis by wild‐type human serum paraoxonase
2007
·
David T. Yeung
, J. Richard Smith
, et al.
·
FEBS Journal
·
43
PDF
Butyrylcholinesterase as a therapeutic drug for protection against percutaneous VX
2010
·
David E. Lenz
, Edward D. Clarkson
, et al.
·
Chemico-Biological Interactions
·
41
Effect of octanol:water partition coefficients of organophosphorus compounds on biodistribution and percutaneous toxicity
2006
·
Steven E. Czerwinski
, John P. Skvorak
, et al.
·
Journal of Biochemical and Molecular Toxicology
·
40
Studies using a monoclonal antibody against soman*1
1984
·
D LENZ
·
Fundamental and Applied Toxicology
·
40
Mouse monoclonal antibodies against paraoxon: potential reagents for immunoassay with constant immunochemical characteristics
1985
·
Alan A. Brimfield
, David E. Lenz
, et al.
·
Journal of Agricultural and Food Chemistry
·
38
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Works count:
93
Citation count:
2,874
H-index:
34
I10-index:
59
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