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Edmund J. Moran
Observed names:
E J Moran,
E Moran,
EDMUND J MORAN,
Edmund J Moran,
Edmund Moran
Institution:
Theravance Biopharma (United States)
Observed institutions:
BC Cancer Agency,
University of California, Los Angeles,
Theravance Biopharma (United States),
University of California, Berkeley
ORCID:
0000-0001-5066-4866
Observed ORCID:
0000-0001-5066-4866
OpenAlex ID:
A5109142964
Works
43
Awards
1
An Unnatural Biopolymer
1993
·
Charles Y. Cho
, Edmund J. Moran
, et al.
·
Science
·
370
Radio Frequency Tag Encoded Combinatorial Library Method for the Discovery of Tripeptide-Substituted Cinnamic Acid Inhibitors of the Protein Tyrosine Phosphatase PTP1B
1995
·
Edmund J. Moran
, Sepehr Sarshar
, et al.
·
Journal of the American Chemical Society
·
261
Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.
2000
·
M J Newman
, J C Rodarte
, et al.
·
PubMed
·
190
Synthesis of tetrasubstituted imidazoles via α-(N-acyl-N-alkylamino)-β-ketoamides on Wang resin
1996
·
Chengzhi Zhang
, Edmund J Moran
, et al.
·
Tetrahedron Letters
·
148
Dehydroamino acid derivatives from D-arabinose and L-serine: synthesis of models for the azinomycin antitumor antibiotics
1993
·
Edmund J. Moran
, John E. Tellew
, et al.
·
The Journal of Organic Chemistry
·
63
2,4,5-Trisubstituted imidazoles
2000
·
Chengzhi Zhang
, Sepehr Sarshar
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
62
Novel biopolymers for drug discovery
1995
·
Edmund J. Moran
, Troy E. Wilson
, et al.
·
Biopolymers
·
59
Exploring the Positional Attachment of Glycopeptide/β-lactam Heterodimers
2008
·
Daniel D Long
, James B Aggen
, et al.
·
The Journal of Antibiotics
·
58
Highly convergent approach to the synthesis of the epoxy-amide fragment of the azinomycins
1991
·
Edmund J. Moran
, Robert W. Armstrong
·
Tetrahedron Letters
·
54
A Multivalent Approach to Drug Discovery for Novel Antibiotics
2008
·
Daniel D Long
, James B Aggen
, et al.
·
The Journal of Antibiotics
·
52
A phase 2 multiple ascending dose study of the inhaled pan-JAK inhibitor nezulcitinib (TD-0903) in severe COVID-19
2021
·
Dave Singh
, Maxim Bogus
, et al.
·
European Respiratory Journal
·
46
PDF
Stereoselective synthesis of (E)- and (Z)-1-azabicyclo[3.1.0]hex-2-ylidene dehydroamino acid derivatives
1992
·
Robert W. Armstrong
, John E. Tellew
, et al.
·
The Journal of Organic Chemistry
·
44
2,4,5-Trisubstituted imidazoles
2000
·
Sepehr Sarshar
, Chengzhi Zhang
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
43
Synthesis of Nh-acyl-α-aminoamides on rink resin: Inhibitors of the hematopoietic protein tyrosine phosphatase (HePTP)
1995
·
Xiaodong Cao
, Edmund J. Moran
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
43
Pharmacodynamics, pharmacokinetics and safety of revefenacin (TD-4208), a long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD): Results of two randomized, double-blind, phase 2 studies
2017
·
Dean Quinn
, Christopher N. Barnes
, et al.
·
Pulmonary Pharmacology & Therapeutics
·
40
PDF
Stereoselective synthesis of a 1-azabicyclo[3.1.0]hex-2-ylidene dehydroamino acid derivative related to the azinomycin antitumor antibiotics
1992
·
Robert W. Armstrong
, Edmund J. Moran
·
Journal of the American Chemical Society
·
37
Revefenacin, a once-daily, lung-selective, long-acting muscarinic antagonist for nebulized therapy: Safety and tolerability results of a 52-week phase 3 trial in moderate to very severe chronic obstructive pulmonary disease
2019
·
James F. Donohue
, Edward Kerwin
, et al.
·
Respiratory Medicine
·
36
Nebulized Versus Dry Powder Long-Acting Muscarinic Antagonist Bronchodilators in Patients With COPD and Suboptimal Peak Inspiratory Flow Rate
2019
·
Donald A. Mahler
, Jill A. Ohar
, et al.
·
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
·
36
A 28-day, randomized, double-blind, placebo-controlled, parallel group study of nebulized revefenacin in patients with chronic obstructive pulmonary disease
2017
·
Krishna K. Pudi
, Chris N. Barnes
, et al.
·
Respiratory Research
·
32
PDF
A multivalent approach to the discovery of long-acting β2-adrenoceptor agonists for the treatment of asthma and COPD
2011
·
John R. Jacobsen
, Seok Ki Choi
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
31
Improvements in Lung Function with Nebulized Revefenacin in the Treatment of Patients with Moderate to Very Severe COPD: Results from Two Replicate Phase III Clinical Trials
2019
·
Gary T. Ferguson
, Gregory Feldman
, et al.
·
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
·
30
PDF
Synthetic studies towards carzinophilin: Synthesis and ammonium hydroxide-induced rearrangement of the epoxi-acid fragment
1990
·
Pamela England
, Ho Chun Keun
, et al.
·
Tetrahedron Letters
·
23
Mono-osmylation of dehydroamino acid dienes: synthesis of dehydroamino acids related to the azinomycins
1996
·
Robert W Armstrong
, John E Tellew
, et al.
·
Tetrahedron Letters
·
21
Simplified method for the isolation of thermally labile drug-DNA adducts: Characterization of chlorambucil and carzinophilin/azinomycin B alkylation products
1992
·
Mark E. Salvati
, Edmund J. Moran
, et al.
·
Tetrahedron Letters
·
18
Maintained therapeutic effect of revefenacin over 52 weeks in moderate to very severe Chronic Obstructive Pulmonary Disease (COPD)
2019
·
James F. Donohue
, Edward Kerwin
, et al.
·
Respiratory Research
·
16
PDF
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Works count:
43
Citation count:
1,878
H-index:
22
I10-index:
27
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