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Manuel A. Ortega
Observed names:
M.A. Ortega,
Manuel Ortega,
Manuel A. Ortega,
Ortega, Manuel A.
Institution:
Beam Therapeutics (United States)
Observed institutions:
Howard Hughes Medical Institute,
University of Illinois Urbana-Champaign,
Beam Therapeutics (United States),
Carl R. Woese Institute for Genomic Biology,
University of Puerto Rico-Mayaguez,
Massachusetts Institute of Technology
show all 6
ORCID:
0000-0003-2213-9516
Observed ORCID:
0000-0003-2213-9516
OpenAlex ID:
A5109477608
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB
2014
·
Manuel A. Ortega
, Yue Hao
, et al.
·
Nature
·
321
New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products
2016
·
Manuel A. Ortega
, Wilfred A. van der Donk
·
Cell chemical biology
·
302
PDF
Improved cytosine base editors generated from TadA variants
2023
·
Dieter K. Lam
, Patricia R. Feliciano
, et al.
·
Nature Biotechnology
·
146
PDF
Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis
2016
·
Manuel A. Ortega
, Dillon P. Cogan
, et al.
·
ACS Chemical Biology
·
82
Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis
2016
·
Manuel A. Ortega
, Yue Hao
, et al.
·
Cell chemical biology
·
78
PDF
Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS
2014
·
Qi Zhang
, Manuel Ortega
, et al.
·
Proceedings of the National Academy of Sciences
·
67
Substrate Specificity of the Lanthipeptide Peptidase ElxP and the Oxidoreductase ElxO
2014
·
Manuel A. Ortega
, Juan E. Velásquez
, et al.
·
ACS Chemical Biology
·
42
PDF
Association of toll-like receptor four single nucleotide polymorphisms with incidence of infectious bovine keratoconjunctivitis (IBK) in cattle
2010
·
Ranjit S. Kataria
, Richard G. Tait
, et al.
·
Immunogenetics
·
33
Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria
2020
·
Maud Bollenbach
, Manuel Ortega
, et al.
·
ACS Medicinal Chemistry Letters
·
29
Conversion of HbS to Hb G-Makassar By Adenine Base Editing Is Compatible with Normal Hemoglobin Function
2021
·
S. Haihua Chu
, Manuel Ortega
, et al.
·
Blood
·
20
Molecular Basis of Bacillus subtilis ATCC 6633 Self-Resistance to the Phosphono-oligopeptide Antibiotic Rhizocticin
2019
·
Nektaria Petronikolou
, Manuel A. Ortega
, et al.
·
ACS Chemical Biology
·
18
Base editing HbS to HbG-Makassar improves hemoglobin function supporting its use in sickle cell disease
2025
·
Zachary Kostamo
, Manuel A. Ortega
, et al.
·
Nature Communications
·
14
PDF
wild-type choline TMA lyase in complex with 1-methyl-1,2,3,6-tetrahydropyridin-3-ol
2020
·
M.A. Ortega
, C.L. Drennan
·
Worldwide Protein Data Bank
Biochemical characterization of enzymes involved in the post-translational modification of lantibiotics
2015
·
Manuel A. Ortega
·
Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
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Works count:
15
Citation count:
1,152
H-index:
12
I10-index:
12
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