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Wai-Kwong Eng

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
1999 · Priya Chaturvedi, Wai K Eng, et al. · Oncogene · 430
Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin.
1988 · W K Eng, L Faucette, et al. · Molecular Pharmacology · 325
Dominant Missense Mutations in a Novel Yeast Protein related to Mammalian Phosphatidylinositol 3-Kinase and VPS34 Abrogate Rapamycin Cytotoxicity
1993 · R Cafferkey, P R Young, et al. · Molecular and Cellular Biology · 322
Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content.
1990 · W K Eng, F L McCabe, et al. · Molecular Pharmacology · 126
Mapping of the Active Site Tyrosine of Eukaryotic DNA Topoisomerase I
1989 · W K Eng, S D Pandit, et al. · Journal of Biological Chemistry · 91
The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth
1994 · Wai-Kwong Eng, Leo Faucette, et al. · Gene · 86
Dimethonium, a divalent cation that exerts only a screening effect on the electrostatic potential adjacent to negatively charged phospholipid bilayer membranes
1983 · Alan McLaughlin, Wai-Kwong Eng, et al. · The Journal of Membrane Biology · 81
Signal-Mediated Import of Bacteriophage T7 RNA Polymerase into the Saccharomyces cerevisiae Nucleus and Specific Transcription of Target Genes
1990 · B M Benton, W K Eng, et al. · Molecular and Cellular Biology · 73
Use of COMPARE Analysis to Discover New Natural Product Drugs: Isolation of Camptothecin and 9-Methoxycamptothecin from a New Source
2000 · Bing-Nan Zhou, Jeannine M. Hoch, et al. · Journal of Natural Products · 72
Camptothecin hyper-resistant P388 cells: drug-dependent reduction in topoisomerase I content.
1992 · R D Woessner, W K Eng, et al. · PubMed · 72
The CYP2 gene of Saccharomyces cerevisiae encodes a cyclosporin A-sensitive peptidyl-prolyl cis-trans isomerase with an N-terminal signal sequence
1991 · Paul L. Koser, Derk J. Bergsma, et al. · Gene · 35
The tyrosine89 residue of yeast FKBP12 is required for rapamycin binding
1993 · Paul L Koser, Wai-Kwong Eng, et al. · Gene · 33
Expression of human recombinant cAMP phosphodiesterase isozyme IV reverses growth arrest phenotypes in phosphodiesterase-deficient yeast.
1991 · M M McHale, L B Cieslinski, et al. · Molecular Pharmacology · 26
Catalytic and ligand binding properties of the FK506 binding protein FKBP12: effects of the single amino acid substitution of Tyr82 to Leu
1994 · M J Bossard, D J Bergsma, et al. · Biochemical Journal · 22
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Works count: 14
Citation count: 1,794
H-index: 14
I10-index: 14
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