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Cho Tang

Observed names: C K Tang, C Tang, C. -K. Tang, C. TANG, C. Tang, C.-K. TANG, C.-K. Tang, C.K. TANG, C.K. Tang, C. K. Tang
OpenAlex ID: A5109929431
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
2003 · Dirk B Mendel, A Douglas Laird, et al. · PubMed · 1,956
Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors
1997 · Moosa Mohammadi, Gerald McMahon, et al. · Science · 1,098
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.
1999 · T A Fong, L K Shawver, et al. · PubMed · 1,026
Discovery of 5-[5-Fluoro-2-oxo-1,2- dihydroindol-(3 Z )-ylidenemethyl]-2,4- dimethyl-1 H -pyrrole-3-carboxylic Acid (2-Diethylaminoethyl)amide, a Novel Tyrosine Kinase Inhibitor Targeting Vascular Endothelial and Platelet-Derived Growth Factor Receptor Tyrosine Kinase
2003 · Li Sun, Chris Liang, et al. · Journal of Medicinal Chemistry · 540
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.
2000 · A D Laird, P Vajkoczy, et al. · PubMed · 494
Synthesis and Biological Evaluations of 3-Substituted Indolin-2-ones: A Novel Class of Tyrosine Kinase Inhibitors That Exhibit Selectivity toward Particular Receptor Tyrosine Kinases
1998 · Li Sun, Ngoc Tran, et al. · Journal of Medicinal Chemistry · 493
Flk-1 as a target for tumor growth inhibition.
1996 · L M Strawn, G McMahon, et al. · PubMed · 316
Design, Synthesis, and Evaluations of Substituted 3-[(3- or 4-Carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as Inhibitors of VEGF, FGF, and PDGF Receptor Tyrosine Kinases
1999 · Li Sun, Ngoc Tran, et al. · Journal of Medicinal Chemistry · 267
Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.
1997 · L K Shawver, D P Schwartz, et al. · PubMed · 130
Identification of Substituted 3-[(4,5,6,7-Tetrahydro-1H-indol-2-yl)methylene]- 1,3-dihydroindol-2-ones as Growth Factor Receptor Inhibitors for VEGF-R2 (Flk-1/KDR), FGF-R1, and PDGF-Rβ Tyrosine Kinases
2000 · Li Sun, Ngoc Tran, et al. · Journal of Medicinal Chemistry · 113
Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine
2006 · Guan-Sheng Jiao, Lynne Cregar, et al. · Proceedings of the National Academy of Sciences · 91
SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization
2003 · Ismail Hassan Ismail, Susanne Mårtensson, et al. · Oncogene · 84
Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases
2003 · Ping Huang, John Ramphal, et al. · Bioorganic & Medicinal Chemistry · 58
Design and synthesis of aminopropyl tetrahydroindole-based indolin-2-ones as selective and potent inhibitors of Src and Yes tyrosine kinase
2003 · Huiping Guan, A.Douglas Laird, et al. · Bioorganic & Medicinal Chemistry Letters · 57
Weekly Dosing With the Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitor SU9518 Significantly Inhibits Arterial Stenosis
2001 · Yasundo Yamasaki, Kazuhisa Miyoshi, et al. · Circulation Research · 54
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Effects of Temperature on the Interaction of Morphine With Opioid Receptors
1987 · M.M. PUIG, W. WARNER, et al. · British Journal of Anaesthesia · 49
Growth inhibition of psoriatic keratinocytes by quinazoline tyrosine kinase inhibitors
1999 · T.J. Powell, H. Ben-Bassat, et al. · British Journal of Dermatology · 44
A Selective and Oral Small Molecule Inhibitor of Vascular Epithelial Growth Factor Receptor (VEGFR)-2 and VEGFR-1 Inhibits Neovascularization and Vascular Permeability
2003 · Neela Patel, Li Sun, et al. · Journal of Pharmacology and Experimental Therapeutics · 41
A One-Pot, Two-Step Synthesis of Tetrahydro Asterriquinone E
1999 · G. Davis Harris,, Ann Nguyen, et al. · Organic Letters · 38
Novel pyrrolyllactone and pyrrolyllactam indolinones as potent cyclin-Dependent kinase 2 inhibitors
2003 · Xiaoyuan Li, Ping Huang, et al. · Bioorganic & Medicinal Chemistry Letters · 37
Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185erbB) tyrosine kinases
2002 · Li Sun, Jean Cui, et al. · Bioorganic & Medicinal Chemistry Letters · 29
Guanidinylated 2,5-dideoxystreptamine derivatives as anthrax lethal factor inhibitors
2006 · Guan-Sheng Jiao, Lynne Cregar, et al. · Bioorganic & Medicinal Chemistry Letters · 25
Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease
2006 · Guan-Sheng Jiao, Ondrej Simo, et al. · Bioorganic & Medicinal Chemistry Letters · 15
Effects of Mu receptor agonists and droperidol on motor coordination in mice
1988 · M. Bansinath, J.S. Fisher, et al. · Pharmacology Biochemistry and Behavior · 14
Synergistic Interaction of Morphine and Halothane in the Guinea Pig Ileum
1988 · M. M. Puig, W. Warner, et al. · Anesthesiology · 12
Works count: 42
Citation count: 7,106
H-index: 22
I10-index: 26
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