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Guy Miller

Initial experience in the treatment of inherited mitochondrial disease with EPI-743
2011 · Gregory M. Enns, Stephen L. Kinsman, et al. · Molecular Genetics and Metabolism · 202
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Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase
2018 · Andrew Hinman, Charles R. Holst, et al. · PLoS ONE · 198
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EPI-743 reverses the progression of the pediatric mitochondrial disease—Genetically defined Leigh Syndrome
2012 · Diego Martinelli, Michela Catteruccia, et al. · Molecular Genetics and Metabolism · 197
Effect of EPI-743 on the Clinical Course of the Mitochondrial Disease Leber Hereditary Optic Neuropathy
2012 · Alfredo A. Sadun, Carlos Filipe Chicani, et al. · Archives of Neurology · 175
Alpha and gamma tocopherol metabolism in healthy subjects and patients with end-stage renal disease
2003 · Jonathan Himmelfarb, Jane Kane, et al. · Kidney International · 116
Gamma-Tocopherol and Docosahexaenoic Acid Decrease Inflammation in Dialysis Patients
2007 · Jonathan Himmelfarb, Stephen Phinney, et al. · Journal of Renal Nutrition · 105
α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging
2011 · William D. Shrader, Akiko Amagata, et al. · Bioorganic & Medicinal Chemistry Letters · 98
A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial
2012 · David R. Lynch, Steven M. Willi, et al. · Movement Disorders · 94
Glutathione: A redox signature in monitoring EPI-743 therapy in children with mitochondrial encephalomyopathies
2013 · Anna Pastore, Sara Petrillo, et al. · Molecular Genetics and Metabolism · 64
Brain uptake of Tc99m-HMPAO correlates with clinical response to the novel redox modulating agent EPI-743 in patients with mitochondrial disease
2012 · Francis G. Blankenberg, Stephen L. Kinsman, et al. · Molecular Genetics and Metabolism · 36
Japanese Leigh syndrome case treated with EPI-743
2017 · Takeshi Kouga, Mariko Takagi, et al. · Brain and Development · 27
Towards a modern definition of vitamin E—evidence for a quinone hypothesis
2011 · William D. Shrader, Akiko Amagata, et al. · Bioorganic & Medicinal Chemistry Letters · 14
Comparing EPI-743 treatment in siblings with Leber's Hereditary Optic Neuropathy mt14484 mutation
2013 · Carlos F. Chicani, Edward R. Chu, et al. · Canadian Journal of Ophthalmology · 12
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EPI-743 for Friedreichs Ataxia Patients with Point Mutations (P5.388)
2016 · Kelly Sullivan, Mary Freeman, et al. · Neurology · 9
EPI-743 Improves Motor Function and CNS Biomarkers in PD: Results from a Phase 2A Pilot Trial (I1.012)
2016 · Theresa Zesiewicz, Kevin Allison, et al. · Neurology · 5
Treatment of Leber's hereditary optic neuropathy (LHON): Results using a novel quinone, EPI-743
2013 · Carlos Filipe Chicani, Edward Chu, et al. · Investigative Ophthalmology & Visual Science · 3
EPI-743 Improves Motor Function and CNS Biomarkers in PD: Results from a Phase 2A Pilot Trial (S40.004)
2016 · Theresa Zesiewicz, Kevin Allison, et al. · Neurology · 2
EPI-743 May Improve Visual Acuity in LHON: Data from a Brazilian Cohort
2014 · Amitha Ganti, Edward R. Chu, et al. · Investigative Ophthalmology & Visual Science · 2
EPI-743: Preliminary report on Italian experience in open label study of three patients with acute Leber's hereditary optic neuropathy
2012 · Valerio Carelli, Piero Barboni, et al. · Mitochondrion · 2
Proteomic profiling identifies molecular basis of adverse event to BPM31510 exposure: Rationale for comprehensive molecular pharmacodynamics (PD) in phase I clinical trial design
2019 · V. Subbiah, E. Granger, et al. · Annals of Oncology · 1
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Streamlining multi-omic and artificial intelligence analysis through interrogative biology and baicis for translational precision medicine applications in clinical oncology
2018 · L. Rodrigues, M.A. Kiebish, et al. · Annals of Oncology · 1
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EPI-743 (Quinone) therapy for Leber’s Hereditary Optic Neuropathy: the Brazil experience.
2016 · Supanut Apinyawasisuk, Amitha Ganti, et al. · Investigative Ophthalmology & Visual Science · 1
EPI-743 for Freidreich’s Ataxia Point Mutations
2016 · Kelly L. Sullivan, Mary Freeman, et al.
Treatment of Leber's hereditary optic neuropathy with EPI ‐743: the Brazilian experience
2015 · R. Karanjia, A. Ganti, et al. · Acta Ophthalmologica
Leber’s Hereditary Optic Neuropathy (LHON) Open Label Clinical Study for EPI-743: 2015 update
2015 · Rustum Karanjia, Edward R. Chu, et al. · Investigative Ophthalmology & Visual Science
Works count: 27
Citation count: 1,364
H-index: 12
I10-index: 13
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