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Jean René Kiechel

Observed names: J R Kiechel, J. R. Kiechel, J.R. Kiechel, Jean R Kiechel, Jean R. Kiechel
OpenAlex ID: A5110010071
Fluoronaphthyridines and quinolones as antibacterial agents. 2. Synthesis and structure-activity relationships of new 1-tert-butyl 7-substituted derivatives
1990 · D. Bouzard, P. Di Cesare, et al. · Journal of Medicinal Chemistry · 79
Species differences in metabolism of ketotifen in rat, rabbit and man: Demonstration of similar pathways and in cultured hepatocytes
1987 · J.F. Le Bigot, J.M. Begue, et al. · Life Sciences · 77
Pharmacokinetics and metabolism of guanfacine in man: a review.
1980 · J.R. Kiechel · British Journal of Clinical Pharmacology · 72
Cultured human adult hepatocytes: a new model for drug metabolism studies
1983 · Jean M. Begue, Jean F. Le Bigot, et al. · Biochemical Pharmacology · 69
The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum
2009 · Sodiomon B Sirima, Alfred B Tiono, et al. · Malaria Journal · 63
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The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network
2020 · Mohammad S. Hossain, Robert J. Commons, et al. · PLoS Medicine · 55
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Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug.
1987 · S Urien, J L Pinquier, et al. · Journal of Pharmacology and Experimental Therapeutics · 46
Biopharmaceutical Aspects
1978 · H. Eckert, J. R. Kiechel, et al. · Springer eBooks · 36
Artesunate-amodiaquine fixed dose combination for the treatment of Plasmodium falciparum malaria in India
2012 · Anupkumar R Anvikar, Bhawna Sharma, et al. · Malaria Journal · 29
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Metabolism of ketotifen by human liver microsomes. In vitro characterization of a tertiary amine glucuronidation.
1983 · J F Le Bigot, T Cresteil, et al. · Drug Metabolism and Disposition · 28
Quantification of ketotifen and its metabolites in human plasma by gas chromatography mass spectrometry
1983 · C. Julien-Larose, M. Guerret, et al. · Journal of Mass Spectrometry · 25
Metabolites of Pindolol in Different Animal Species
1975 · J. R. Kiechel, P. Niklaus, et al. · Xenobiotica · 21
Novel routes of drug metabolism. A survey.
1977 · Z H Israili, P G Dayton, et al. · Drug Metabolism and Disposition · 18
Estimation of the absolute oral bioavailability of pindolol by two analytical methods
1983 · M. Guerret, G. Cheymol, et al. · European Journal of Clinical Pharmacology · 16
Determination of pindolol in biological fluids by electron-capture GLC
1980 · M. Guerret, D. Lavene, et al. · Journal of Pharmaceutical Sciences · 16
Determination of sub-nanogram amounts of dihydroergotamine in plasma and urine using liquid chromatography and fluorimetric detection with off-line and on-line solid-phase drug enrichment
1987 · H. Humbert, J. Denouel, et al. · Journal of Chromatography B Biomedical Sciences and Applications · 13
Biotransformation of Drugs during Aging
2009 · J.R. Kiechel · Gerontology · 12
Interaction of dihydroergotamine and triacetyloleandomycin in the minipig
1983 · M. Martinet, J. R. Kiechel · European Journal of Drug Metabolism and Pharmacokinetics · 11
Determination of guanfacine in human plasma by GC-MS with electron capture negative chemical ionization.
1983 · C. Julien-Larose, C. Lange, et al. · International Journal of Mass Spectrometry and Ion Physics · 9
Determination of 3-hydroxy-guanfacine in biological fluids by electron-capture gas—liquid chromatography
1982 · M. Guerret, C. Julien-Larose, et al. · Journal of Chromatography B Biomedical Sciences and Applications · 8
Pharmacokinetics of guanfacine in patients with impaired renal function and in some elderly patients
1986 · Jean R. Kiechel · The American Journal of Cardiology · 7
Presence of phase I and phase II drug metabolizing enzymes in cultured human foetal hepatocytes
1982 · André Guillouzo, Jean F. Le Bigot, et al. · Biochemical Pharmacology · 7
Temporal distribution of Plasmodium falciparum recrudescence following artemisinin-based combination therapy: an individual participant data meta-analysis
2022 · The WorldWide Antimalarial Resistance Network Methodology Study Group, Prabin Dahal, et al. · Malaria Journal · 5
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Pharmacokinetic aspects of guanfacine withdrawal syndrome in a hypertensive patient with chronic renal failure
1983 · J. R. Kiechel, D. Lavene, et al. · European Journal of Clinical Pharmacology · 5
Pindolol: Disposition and metabolism in rhesus monkeys after chronic treatment
1981 · G. Maurer, P. Donatsch, et al. · Xenobiotica · 5
Works count: 36
Citation count: 747
H-index: 15
I10-index: 18
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