Author

Tracey Fiedler

Observed name: Tracey E. Fiedler

Institution: Bristol-Myers Squibb (United States)

Observed institution: Bristol-Myers Squibb (United States)

OpenAlex ID: A5110059914

The Amyloid-β Rise and γ-Secretase Inhibitor Potency Depend on the Level of Substrate Expression

2008 · Catherine R. Burton, Jere E. Meredith, et al. · Journal of Biological Chemistry · 65

Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels

2008 · Robert G. Gentles, Katherine Grant-Young, et al. · Bioorganic & Medicinal Chemistry Letters · 46

P-Glycoprotein Efflux and Other Factors Limit Brain Amyloid β Reduction by β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitors in Mice

2008 · Jere E. Meredith, Lorin A. Thompson, et al. · Journal of Pharmacology and Experimental Therapeutics · 41

2-Arylaminothiazoles as high-affinity corticotropin-Releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy

2003 · Gene M. Dubowchik, Jodi A. Michne, et al. · Bioorganic & Medicinal Chemistry Letters · 20

Synthesis, structure–activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists

2005 · Xiaojun Han, Jodi A. Michne, et al. · Bioorganic & Medicinal Chemistry Letters · 17

Ex Vivo Occupancy of γ-Secretase Inhibitors Correlates with Brain β-Amyloid Peptide Reduction in Tg2576 Mice

2007 · Margi E. Goldstein, Yang Cao, et al. · Journal of Pharmacology and Experimental Therapeutics · 11

An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes

2007 · Xiaojun Han, Rita Civiello, et al. · Bioorganic & Medicinal Chemistry Letters · 8

Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R)

2010 · Vivekananda M. Vrudhula, Bireshwar Dasgupta, et al. · Bioorganic & Medicinal Chemistry Letters · 5

Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine KCa channel blockers

2008 · Robert G. Gentles, Shuanghua Hu, et al. · Bioorganic & Medicinal Chemistry Letters · 5

P4‐020: Separation of Aβ Reduction from Notch Toxicity with Gamma Secretase Inhibitors in Rats

2010 · Jere Meredith, Donna Barten, et al. · Alzheimer s & Dementia · 3

P2‐346: PGP efflux and other factors limit brain Aβ reduction by BACE1 inhibitors in mice

2008 · Jere Meredith, Lorin Thompson, et al. · Alzheimer s & Dementia · 1

P3‐187: Microtubule stabilizing agents as tools to explore the mechanism of Tau neurotoxicity in Alzheimer's disease and other Tauopathies

2009 · Donna M. Barten, Jere E. Meredith, et al. · Alzheimer s & Dementia

P4–308: γ–secretase inhibitors differentially increase or decrease N–terminal variants of rat brain Aβ

2006 · Donna M. Barten, Nina Hoque, et al. · Alzheimer s & Dementia

P2-122 Detection of Nβ peptide and quantitation of its inhibition by γ-secretase inhibitors

2004 · Jeremy Toyn, Tracey Fiedler, et al. · Neurobiology of Aging

Works count: 14

Citation count: 222

H-index: 7

I10-index: 6