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Pamela S. Keim

Observed names: PAMELA S. KEIM, Pam S. Keim, Pamela Keim, Pamela S Keim
OpenAlex ID: A5110070967
Purification and cloning of amyloid precursor protein β-secretase from human brain
1999 · Sukanto Sinha, John P. Anderson, et al. · Nature · 1,597
Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor
1990 · Fred S. Esch, Pamela S. Keim, et al. · Science · 1,401
Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease
2006 · John P. Anderson, Donald E. Walker, et al. · Journal of Biological Chemistry · 1,397
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells
1991 · John P. Anderson, Fred S. Esch, et al. · Neuroscience Letters · 212
Arylphorin, a new protein from Hyalophora cecropia: Comparisons with calliphorin and manducin
1983 · William H. Telfer, Pamela S. Keim, et al. · Insect Biochemistry · 152
Cells with a familial Alzheimerʼs disease mutation produce authentic β-peptide
1993 · Harry F. Dovey, Susanna Suomensaari-Chrysler, et al. · Neuroreport · 71
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease
2010 · Guriqbal S Basi, Susanna Hemphill, et al. · Alzheimer s Research & Therapy · 53
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Partial structural analysis of the basic chromosomal protein of rat spermatozoa
1976 · W. Stephen Kistler, Pamela S. Keim, et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure · 43
Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors
2009 · Anh P. Truong, Danielle L. Aubele, et al. · Bioorganic & Medicinal Chemistry Letters · 37
Discovery of (R)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): Metabolically Stable γ-Secretase Inhibitors that Selectively Inhibit the Production of Amyloid-β over Notch
2013 · Gary Probst, Danielle L. Aubele, et al. · Journal of Medicinal Chemistry · 36
Why Are Green Caterpillars Green?
1985 · JOHN K. KAWOOYA, PAMELA S. KEIM, et al. · ACS symposium series · 36
Crotalus adamanteus phospholipase A2-α: Subunit structure, NH2-terminal sequence, and homology with other phospholipases
1975 · Francis H.C. Tsao, Pamela S. Keim, et al. · Archives of Biochemistry and Biophysics · 28
The covalent structure of pig kidney fructose 1,6-bisphosphatase: sequence of the 60-residue NH2-terminal peptide produced by digestion with subtilisin
1981 · Frank Marcus, Ida Edelstein, et al. · Archives of Biochemistry and Biophysics · 27
Juvenile hormone carrier protein of Manduca sexta haemolymph. Improved purification procedure; protein modification studies and sequence of the amino terminus of the protein
1982 · Ronald C. Peterson, Peter E. Dunn, et al. · Insect Biochemistry · 22
Covalent structure of apolipoprotein A-II from Macaca mulatta serum high-density lipoproteins
1976 · Celina Edelstein, Claudia Noyes, et al. · Biochemistry · 21
Discovery of sulfonamide–pyrazole γ-secretase inhibitors
2010 · Matthew N. Mattson, Martin L. Neitzel, et al. · Bioorganic & Medicinal Chemistry Letters · 18
Isolation of two neuropeptides in the AKH/RPCH-family from horseflies (diptera)
1988 · Howard Jaffe, Ashok K. Raina, et al. · Biochemical and Biophysical Research Communications · 18
A Comprehensive Approach to Amino Acid Analysis
1989 · David R. Dupont, Pamela S. Keim, et al. · Elsevier eBooks · 16
Precursors in the Biosynthesis of Insulin and Other Peptide Hormones
1979 · Shu J. Chan, Christoph Patzelt, et al. · Elsevier eBooks · 12
On the size and chemical nature of the polypeptide chain of bovine liver rhodanese
1975 · John Russell, Litai Weng, et al. · Biochemical and Biophysical Research Communications · 12
Structural studies of Bacillus subtilis glutamine synthetase
1977 · Robert Hsu, Sherwin J. Singer, et al. · Archives of Biochemistry and Biophysics · 4
Corrigendum to “Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors” [Bioorg. Med. Chem. Lett. 19 (2009) 4920]
2010 · Anh P. Truong, Danielle L. Aubele, et al. · Bioorganic & Medicinal Chemistry Letters · 1
P4-183 Molecular determinants of substrate recognition by the Alzheimer amyloid peptide generating protease, β-secretase (BACE)
2004 · John P. Anderson, Pamela S. Keim, et al. · Neurobiology of Aging
Works count: 24
Citation count: 5,214
H-index: 17
I10-index: 20
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