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Edward K. Mberu

Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?
2001 · Carol Hopkins Sibley, John E Hyde, et al. · Trends in Parasitology · 369
Towards an Understanding of the Mechanism of Pyrimethamine-Sulfadoxine Resistance in Plasmodium falciparum : Genotyping of Dihydrofolate Reductase and Dihydropteroate Synthase of Kenyan Parasites
2000 · A. M. Nzila, E. K. Mberu, et al. · Antimicrobial Agents and Chemotherapy · 232
Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania
2001 · Theonest Mutabingwa, Alexis Nzila, et al. · The Lancet · 178
The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses
1997 · W.M. Watkins, E.K. Mberu, et al. · Parasitology Today · 156
Molecular Evidence of Greater Selective Pressure for Drug Resistance Exerted by the Long‐Acting Antifolate Pyrimethamine/Sulfadoxine Compared with the Shorter‐Acting Chlorproguanil/Dapsone on KenyanPlasmodium falciparum
2000 · Alexis M. Nzila, Eunice Nduati, et al. · The Journal of Infectious Diseases · 135
Potent antimalarial activity of the alkaloid nitidine, isolated from a Kenyan herbal remedy
1995 · D M Gakunju, E K Mberu, et al. · Antimicrobial Agents and Chemotherapy · 124
Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain
1998 · A. Nzila-Mounda, E. K. Mberu, et al. · Antimicrobial Agents and Chemotherapy · 109
A new antiplasmodial coumarin from Toddalia asiatica roots
2000 · Hellen A Oketch-Rabah, Julius W Mwangi, et al. · Fitoterapia · 93
The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study
1997 · S.A. Murphy, E. Mberu, et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene · 70
The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non‐severe falciparum malaria.
1992 · PA Winstanley, WM Watkins, et al. · British Journal of Clinical Pharmacology · 69
The changing in vitro susceptibility pattern to pyrimethamine/sulfadoxine in Plasmodium falciparum field isolates from Kilifi, Kenya.
2000 · E K Mberu, M K Mosobo, et al. · American Journal of Tropical Medicine and Hygiene · 61
Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration
1993 · Peter Winstanley, Charles Newton, et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene · 57
Inter‐subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man.
1989 · SA Ward, WM Watkins, et al. · British Journal of Clinical Pharmacology · 54
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Variability in the metabolism of proguanil to the active metabolite cycloguanil in healthy Kenyan adults
1990 · W.M. Watkins, E.K. Mberu, et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene · 52
In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs
1995 · P A Winstanley, E K Mberu, et al. · Antimicrobial Agents and Chemotherapy · 48
The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug.
1999 · S M Kinyanjui, E K Mberu, et al. · American Journal of Tropical Medicine and Hygiene · 42
Antimalarial activity in crude extracts of Malawian medicinal plants
1996 · M. P. E. Connelly, E. Fabiano, et al. · Annals of Tropical Medicine and Parasitology · 41
Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?
2001 · Carol Hopkins Sibley, John E Hyde, et al. · Trends in Parasitology · 34
More on ‘The Efficacy of Antifolate Antimalarial Combinations in Africa'
1999 · W.M. Watkins, E.K. Mberu, et al. · Parasitology Today · 32
Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance
2002 · Edward K Mberu, Alexis M Nzila, et al. · Experimental Parasitology · 31
Antimalarial Activity of Some Kenyan Medicinal Plants
1999 · H.A Oketch-Rabah, S.F. Dossaji, et al. · Pharmaceutical Biology · 29
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Differential extraction of artemether and its metabolite dihydroartemisinin from plasma and determination by high-performance liquid chromatography
1994 · D.K. Muhia, E.K. Mberu, et al. · Journal of Chromatography B Biomedical Sciences and Applications · 29
Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: unbound quinine concentrations following a simple loading dose regimen
1994 · P.A. Winstanley, E.K. Mberu, et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene · 29
Prophylactic phenobarbitone in young children with severe falciparum malaria: pharmacokinetics and clinical effects.
1992 · PA Winstanley, CR Newton, et al. · British Journal of Clinical Pharmacology · 28
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Measurement of quinine in filter paper-absorbed blood by high-performance liquid chromatography
1991 · E.K. Mberu, S.A. Ward, et al. · Journal of Chromatography B Biomedical Sciences and Applications · 22
Works count: 39
Citation count: 2,253
H-index: 24
I10-index: 32
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