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Y. Shigeta

Glucose, Insulin and Somatostatin Infusion for the Determination of Insulin Sensitivity
1977 · Y. Harano, S. Ohgaku, et al. · The Journal of Clinical Endocrinology & Metabolism · 150
Effects of a new aldose reductase inhibitor on various tissues in vitro.
1984 · H Terashima, K Hama, et al. · Journal of Pharmacology and Experimental Therapeutics · 139
Long‐term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic neuropathy
2012 · N. Hotta, R. Kawamori, et al. · Diabetic Medicine · 136
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Abnormal glutathione metabolism and increased cytotoxicity caused by H 2 O 2 in human umbilical vein endothelial cells cultured in high glucose medium
1994 · A. Kashiwagi, T. Asahina, et al. · Diabetologia · 124
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Effect of a new aldose reductase inhibitor, (E)-3-carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodanine (ONO-2235) on peripheral nerve disorders in streptozotocin-diabetic rats
1983 · R. Kikkawa, I. Hatanaka, et al. · Diabetologia · 113
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Translocation of protein kinase C ? and ? in rat glomerular mesangial cells cultured under high glucose conditions
1994 · R. Kikkawa, M. Haneda, et al. · Diabetologia · 109
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Clinical investigation of epalrestat, an aldose reductase inhibitor, on diabetic neuropathy in Japan: Multicenter study
1996 · Nigishi Hotta, Nobuo Sakamoto, et al. · Journal of Diabetes and its Complications · 92
Phosphorylation of carnitine palmitoyltransferase and activation by glucagon in isolated rat hepatocytes
1985 · Y. Harano, A. Kashiwagi, et al. · FEBS Letters · 92
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Direct automated assay method for serum or urine levels of ketone bodies
1985 · Y. Harano, M. Ohtsuki, et al. · Clinica Chimica Acta · 87
Effects of an aldose reductase inhibitor, epalrestat, on diabetic neuropathy. Clinical benefit and indication for the drug assessed from the results of a placebo-controlled double-blind study
1995 · Y Goto, N Hotta, et al. · Biomedicine & Pharmacotherapy · 85
Effect of Combination Therapy of Troglitazone and Sulphonylureas in Patients with Type 2 Diabetes Who Were Poorly Controlled by Sulphonylurea Therapy Alone
1996 · Y. Iwamoto, K. Kosaka, et al. · Diabetic Medicine · 79
Sensitive and simplified method for the differential determination of serum levels of ketone bodies
1983 · Y. Harano, K. Kosugi, et al. · Clinica Chimica Acta · 77
Glucose, insulin, and somatostatin infusion for the determination of insulin sensitivity in vivo
1978 · Y. Harano, H. Hidaka, et al. · Metabolism · 74
Clinical Significance of Altered Insulin Sensitivity in Diabetes Mellitus Assessed by Glucose, Insulin, and Somatostatin Infusion
1981 · Y. HARANO, S. OHGAKU, et al. · The Journal of Clinical Endocrinology & Metabolism · 69
A pilot clinical trial of a new oral hypoglycemic agent, CS-045, in patients with non-insulin dependent diabetes mellitus
1991 · Takeshi Kuzuya, Yasuhiko Iwamoto, et al. · Diabetes Research and Clinical Practice · 53
Characterization of [LeuB-24]- and [LeuB-25]-insulin analogues. Receptor binding and biological activity
1982 · M Kobayashi, S Ohgaku, et al. · Biochemical Journal · 52
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High Glucose Condition Activates Protein Tyrosine Phosphatases and Deactivates Insulin Receptor Function in Insulin-Sensitive Rat 1 Fibroblasts
1994 · R. Ide, H. Maegawa, et al. · Biochemical and Biophysical Research Communications · 51
Stratified analyses for selecting appropriate target patients with diabetic peripheral neuropathy for long‐term treatment with an aldose reductase inhibitor, epalrestat
2008 · N Hotta, R. Kawamori, et al. · Diabetic Medicine · 49
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Enteral absorption of water-in-oil-in-water insulin emulsions in rabbits
1974 · M. Shichiri, Y. Shimizu, et al. · Diabetologia · 46
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Increase in cardiac muscle fructose content in streptozotocin-induced diabetic rats
1992 · Atsunori Kashiwagi, Toshiyuki Obata, et al. · Metabolism · 45
New α2-Adrenergic Blocker (DG-5128) Improves Insulin Secretion and In Vivo Glucose Disposal in NIDDM Patients
1986 · A Kashiwagi, Y Harano, et al. · Diabetes · 43
Ketone bodies as markers for Type 1 (insulin-dependent) diabetes and their value in the monitoring of diabetic control
1984 · Y. Harano, K. Kosugi, et al. · Diabetologia · 38
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Atrial Natriuretic Peptide Inhibits Endothelin-1-Induced Activation of Mitogen-Activated Protein Kinase in Cultured Rat Mesangial Cells
1993 · T. Sugimoto, R. Kikkawa, et al. · Biochemical and Biophysical Research Communications · 37
The effect of an aldose reductase inhibitor (Epalrestat) on diabetic nephropathy in rats
1994 · Iori Itagaki, Kiyoshi Shimizu, et al. · Diabetes Research and Clinical Practice · 35
Alteration of mesangial response to ANP and angiotensin II by glucose
1993 · Masakazu Haneda, Ryuichi Kikkawa, et al. · Kidney International · 30
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Works count: 117
Citation count: 2,641
H-index: 29
I10-index: 57
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