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Author

Lunbin Deng

Observed names: Deng, Lunbin, L Deng, L. Deng, L.B. Deng, 邓伦斌
Institution: Genentech
Observed institutions: Pennsylvania State University, Howard Hughes Medical Institute, Genentech, Peking University, Stanford Medicine, The University of Texas Southwestern Medical Center, Stanford University
OpenAlex ID: A5110198879
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 · Pascal S. Kaeser, Lunbin Deng, et al. · Cell · 606
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Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist
2015 · Shivani Ahuja, Susmith Mukund, et al. · Science · 317
RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13
2011 · Lunbin Deng, Pascal S. Kaeser, et al. · Neuron · 286
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GODZ-Mediated Palmitoylation of GABAAReceptors Is Required for Normal Assembly and Function of GABAergic Inhibitory Synapses
2006 · Cheng Fang, Lunbin Deng, et al. · Journal of Neuroscience · 174
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Formation of an Endophilin-Ca2+ Channel Complex Is Critical for Clathrin-Mediated Synaptic Vesicle Endocytosis
2003 · Yuan Chen, Lunbin Deng, et al. · Cell · 122
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RIM genes differentially contribute to organizing presynaptic release sites
2012 · Pascal S. Kaeser, Lunbin Deng, et al. · Proceedings of the National Academy of Sciences · 115
Hyperpolarization‐activated, cyclic nucleotide‐gated cation channels: Roles in the differential electrophysiological properties of rat primary afferent neurons
2004 · Huiyin Tu, Lunbin Deng, et al. · Journal of Neuroscience Research · 106
RIM1α and RIM1β Are Synthesized from Distinct Promoters of the RIM1 Gene to Mediate Differential But Overlapping Synaptic Functions
2008 · Pascal S. Kaeser, Hyung-Bae Kwon, et al. · Journal of Neuroscience · 100
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ELKS2α/CAST Deletion Selectively Increases Neurotransmitter Release at Inhibitory Synapses
2009 · Pascal S. Kaeser, Lunbin Deng, et al. · Neuron · 99
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Insensitivity to Pain upon Adult-Onset Deletion of Nav1.7 or Its Blockade with Selective Inhibitors
2018 · Shannon D. Shields, Lunbin Deng, et al. · Journal of Neuroscience · 94
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High Ca2+-phosphate transfection efficiency enables single neuron gene analysis
2004 · M Jiang, L Deng, et al. · Gene Therapy · 63
Nav1.7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids
2023 · Lunbin Deng, Michelle Dourado, et al. · Neuron · 60
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Glial cell line-derived neurotrophic factor contributes to delayed inflammatory hyperalgesia in adjuvant rat pain model
2003 · M. Fang, Y. Wang, et al. · Neuroscience · 58
GluN2B Antagonism Affects Interneurons and Leads to Immediate and Persistent Changes in Synaptic Plasticity, Oscillations, and Behavior
2013 · Jesse E Hanson, Martin Weber, et al. · Neuropsychopharmacology · 55
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Cyclothiazide potently inhibits γ-aminobutyric acid type A receptors in addition to enhancing glutamate responses
2003 · Lunbin Deng, Gong Chen · Proceedings of the National Academy of Sciences · 45
A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain
2017 · Tzu-Ming Wang, Brandon M. Brown, et al. · Neuropharmacology · 42
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Sequential Postsynaptic Maturation Governs the Temporal Order of GABAergic and Glutamatergic Synaptogenesis in Rat Embryonic Cultures
2007 · Lunbin Deng, Jun Yao, et al. · Journal of Neuroscience · 41
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Identification of Selective Acyl Sulfonamide–Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na V ) 1.7 with Potent Analgesic Activity
2018 · Shaoyi Sun, Qi Jia, et al. · Journal of Medicinal Chemistry · 35
Histone Deacetylase 2 Cell Autonomously Suppresses Excitatory and Enhances Inhibitory Synaptic Function in CA1 Pyramidal Neurons
2013 · Jesse E. Hanson, Lunbin Deng, et al. · Journal of Neuroscience · 35
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Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease
2014 · Jesse E. Hanson, Jean-Francois Pare, et al. · Neurobiology of Disease · 32
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Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic Pain
2019 · Steven J. McKerrall, Teresa Nguyen, et al. · Journal of Medicinal Chemistry · 31
Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors
2023 · Marc Kschonsak, Christine C Jao, et al. · eLife · 30
Structural Basis of Nav1.7 Inhibition by an Isoform-Selective Small Molecule Antagonist
2016 · David H. Hackos, Shivani Ahuja, et al. · Biophysical Journal · 7
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Lung-innervating neurons expressing Tmc3 can induce broncho-constriction and dilation with direct consequences for the respiratory cycle
2023 · Jens Kortmann, Kevin Huang, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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Author response: Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors
2023 · Marc Kschonsak, Christine C Jao, et al.
Works count: 34
Citation count: 2,552
H-index: 22
I10-index: 22
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