Author

Patrick W. Trown

Observed names: P Trown, P W Trown, P. W. TROWN, P. W. Trown, P.W. TROWN, P.W. Trown, PATRICK TROWN, PATRICK W. TROWN, PatrickW Trown

Observed institutions: F. Hoffmann-La Roche AG, Lawrence Berkeley National Laboratory, Columbia University Irving Medical Center, Green Cross (South Korea), XOMA (United States), Dong-A University, Columbia University, University of California, Berkeley, Stanford University

OpenAlex ID: A5110332044

Recombinant Leukocyte A Interferon: Pharmacokinetics, Single-Dose Tolerance, and Biologic Effects in Cancer Patients

1982 · JORDAN U. GUTTERMAN, SEYMOUR FINE, et al. · Annals of Internal Medicine · 377

Antitumor activity of recombinant-derived interferon alpha in metastatic renal cell carcinoma.

1985 · J R Quesada, A Rios, et al. · Journal of Clinical Oncology · 272

Fluorinated pyrimidine nucleosides. 3. Synthesis and antitumor activity of a series of 5'-deoxy-5-fluoropyrimidine nucleosides

1979 · A. F. Cook, M. J. Holman, et al. · Journal of Medicinal Chemistry · 138

An Improved Method for the Isolation of Carboxydismutase. Probable Identity with Fraction I Protein and the Protein Moiety of Protochlorophyll Holochrome*

1965 · P. W. Trown · Biochemistry · 134

Effects of cloned human leukocyte interferons in the human tumor stem cell assay.

1983 · S E Salmon, B G Durie, et al. · Journal of Clinical Oncology · 124

Incidence and clinical significance of neutralizing antibodies in patients receiving recombinant interferon alfa-2a by intramuscular injection

1987 · Loretta M. Itri, Marilyn Campion, et al. · Cancer · 117

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Antibodies to Human Leucocyte Interferons in Cancer Patients

1983 · PatrickW Trown, RobertA Dennin, et al. · The Lancet · 103

Antiviral activity of N,N′-dimethyl-epidithiapiperazinedione, a synthetic compound related to the gliotoxins, LL-S88α and β, chetomin and the sporidesmins

1968 · P.W. Trown · Biochemical and Biophysical Research Communications · 100

Toxic Properties of a Synthetic Double-stranded RNA: Pyrogenicity of Poly I.Poly C in Rabbits

1969 · H. L. LINDSAY, P. W. TROWN, et al. · Nature · 97

Gene delivery from the E3 region of replicating human adenovirus: evaluation of the 6.7 K/gp19 K region

2001 · LK Hawkins, L Johnson, et al. · Gene Therapy · 90

Specific Inhibition of Viral Ribonucleic Acid Replication by Gliotoxin

1968 · P. A. Miller, K. P. Milstrey, et al. · Science · 83

Relationship between binding affinities to cellular retinoic acid-binding protein and in vivo and in vitro properties for 18 retinoids.

1980 · P W Trown, A V Palleroni, et al. · PubMed · 76

Cell and Virus Sensitivity Studies with Recombinant Human Alpha Interferons

1983 · M.J. KRAMER, R. DENNIN, et al. · Journal of Interferon Research · 69

The preclinical development of roferon®-A

1986 · Patrick W. Trown, Robert J. Wills, et al. · Cancer · 65

Mechanism of Action of Carboxydismutase

1964 · B. R. RABIN, P. W. TROWN · Nature · 59

The detection of antibodies to recombinant interferon alfa-2a in human serum

1987 · U. Hennes, W. Jucker, et al. · Journal of Biological Standardization · 54

Mechanism of Action of Gliotoxin: Elimination of Activity by Sulfhydryl Compounds

1972 · P. W. Trown, J. A. Bilello · Antimicrobial Agents and Chemotherapy · 52

Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model

2009 · J-H Lee, M-S Roh, et al. · Cancer Gene Therapy · 49

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Plasma and Cerebrospinal Fluid Pharmacokinetics of Recombinant Interferon Alpha A in Monkeys: Comparison of Intravenous, Intramuscular, and Intraventricular Delivery

1985 · JERRY M. COLLINS, RICCARDO RICCARDI, et al. · Cancer Drug Delivery · 44

Fluorinated retinoic acids and their analogs. 1. Synthesis and biological activity of (4-methoxy-2,3,6-trimethylphenyl)nonatetraenoic acid analogs

1979 · Beverly A. Pawson, Ka-Kong Chan, et al. · Journal of Medicinal Chemistry · 43

In vivo activity of ceftriaxone (Ro 13-9904), a new broad-spectrum semisynthetic cephalosporin

1981 · G Beskid, J G Christenson, et al. · Antimicrobial Agents and Chemotherapy · 40

Inhibition of Carboxydismutase by Iodoacetamide

1964 · Brian R. Rabin, Patrick W. Trown · Proceedings of the National Academy of Sciences · 40

Measurement of bactericidal/permeability-increasing protein in human body fluids by sandwich ELISA

1994 · Mark L. White, Jeremy K. Ma, et al. · Journal of Immunological Methods · 38

Reactivity of monoclonal antibody E5 with endotoxin. I. Binding to lipid A and rough lipopolysaccharides.

1992 · D M Wood, J B Parent, et al. · PubMed · 30

Improved pharmacokinetics and tumor localization of immunotoxins constructed with the Mr 30,000 form of ricin A chain.

1991 · P W Trown, D T Reardan, et al. · PubMed · 30

Works count: 48

Citation count: 2,535

H-index: 27

I10-index: 34