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Isao Yanagisawa

Observed names: I. YANAGISAWA, ISAO YANAGISAWA, Isao YANAGISAWA, 柳沢勲
OpenAlex ID: A5110346038
Novel potassium channel openers. Part 4: transformation of the 1,4-benzoxazine skeleton into 1,4-benzothiazine, 1,2,3,4-tetrahydroquinoline, 1,2,3,4-tetrahydroquinoxaline, indoline, and 1,5-benzoxazepine
2000 · Yuzo Matsumoto, Ryuji Tsuzuki, et al. · Bioorganic & Medicinal Chemistry · 47
One-Pot Preparation of 1-Substituted Imidazole-2-thione from Isothiocyanate and Amino Acetal
1997 · Koyo Matsuda, Isao Yanagisawa, et al. · Synthetic Communications · 43
Further study on the diterpenes of aralia spp.
1969 · Susumu Mihashi, Isao Yanagisawa, et al. · Tetrahedron Letters · 37
The Discovery of YM-60828: A Potent, Selective and Orally-Bioavailable Factor Xa Inhibitor
2002 · Fukushi Hirayama, Hiroyuki Koshio, et al. · Bioorganic & Medicinal Chemistry · 36
Syntheses and biological evaluation of novel quinuclidine derivatives as squalene synthase inhibitors
2003 · Tsukasa Ishihara, Hirotoshi Kakuta, et al. · Bioorganic & Medicinal Chemistry · 32
Histamine H2 receptor antagonists. 1. Synthesis of N-cyano and N-carbamoyl amidine derivatives and their biological activities
1984 · Isao Yanagisawa, Yasufumi Hirata, et al. · Journal of Medicinal Chemistry · 27
Synthesis and biological evaluation of novel propylamine derivatives as orally active squalene synthase inhibitors
2004 · Tsukasa Ishihara, Hirotoshi Kakuta, et al. · Bioorganic & Medicinal Chemistry · 23
Synthesis and Biological Evaluation of Quinuclidine Derivatives Incorporating Phenothiazine Moieties as Squalene Synthase Inhibitors
2004 · Tsukasa Ishihara, Hirotoshi Kakuta, et al. · Chemical and Pharmaceutical Bulletin · 23
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Alternative Synthesis of Dibenzo-and Dipyrido-[1,3]Diazepines from Thioamides and o,o′-Diaminobiaryls
1997 · Koyo Matsuda, Isao Yanagisawa, et al. · Synthetic Communications · 23
Novel Potassium Channel Activators. II. Synthesis and Pharmacological Evaluation of 3,4-Dihydro-2H-1,4-benzoxazine Derivatives: Modification of the Aromatic Part.
1999 · Yuzo MATSUMOTO, Ryuji TSUZUKI, et al. · Chemical and Pharmaceutical Bulletin · 19
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Novel 5-Hydroxytryptamine (5-HT3) Receptor Antagonists. I. Synthesis and Structure-Activity Relationships of Conformationally Restricted Fused Imidazole Derivatives.
1996 · Mitsuaki OHTA, Takeshi SUZUKI, et al. · Chemical and Pharmaceutical Bulletin · 19
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Antihypertensive activity of a nonpeptide angiotensin II receptor antagonist, YM358, in rats and dogs
1997 · Masayuki Shibasaki, Akira Fujimori, et al. · European Journal of Pharmacology · 15
Ethenesulfonamide and ethanesulfonamide derivatives, a novel class of orally active endothelin-A receptor antagonists
2001 · Hironori Harada, Jun-ichi Kazami, et al. · Bioorganic & Medicinal Chemistry · 14
Novel 5-Hydroxytryptamine (5-HT3) Receptor Antagonists. II. Synthesis and Structure-Activity Relationships of 4,5,6,7-Tetrahydro-1H-benzimidazole Derivatives.
1996 · Mitsuaki OHTA, Takeshi SUZUKI, et al. · Chemical and Pharmaceutical Bulletin · 13
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Synthesis and Biological Evaluation of Phenylacetyl Derivatives Having Low Central Nervous System Permeability as Potent and Selective M2 Muscarinic Receptor Antagonists.
1998 · Toshihiro WATANABE, Akio KAKEFUDA, et al. · Chemical and Pharmaceutical Bulletin · 12
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Studies on Nonpeptide Angiotensin II Receptor Antagonists. I. Synthesis and Biological Evaluation of Pyrazolo(1,5-b)(1,2,4)triazole Derivatives with Alkyl Substituents.
1998 · Toshio OKAZAKI, Akira SUGA, et al. · Chemical and Pharmaceutical Bulletin · 12
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Syntheses of 3-Ethylidenequinuclidine derivatives as squalene synthase inhibitors. Part 2: enzyme inhibition and effects on plasma lipid levels
2003 · Tsukasa Ishihara, Hirotoshi Kakuta, et al. · Bioorganic & Medicinal Chemistry · 11
A novel synthesis of .ALPHA.-halo carbonyl compounds using metal halides.
1976 · NORIYOSHI INUKAI, HIDENORI IWAMOTO, et al. · Chemical and Pharmaceutical Bulletin · 11
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Ethenesulfonamide Derivatives, a Novel Class of Orally Active Endothelin-A Receptor Antagonists
2001 · Hironori HARADA, Jun-ichi KAZAMI, et al. · Chemical and Pharmaceutical Bulletin · 10
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Synthesis and Structure-Activity Relationships in a Series of Ethenesulfonamide Derivatives, a Novel Class of Endothelin Receptor Antagonists.
2001 · Hironori HARADA, Jun-ichi KAZAMI, et al. · Chemical and Pharmaceutical Bulletin · 10
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Synthesis of Novel Succinamide Derivatives Having the 5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one Skeleton as Potent and Selective M2 Muscarinic Receptor Antagonists. I.
1997 · Toshihiro WATANABE, Isao KINOYAMA, et al. · Chemical and Pharmaceutical Bulletin · 10
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Synthesis and Pharmacological Evaluation of 2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinoline Derivatives as Specific Bradycardic Agents.
2003 · Akio Kakefuda, Toshihiro Watanabe, et al. · Chemical and Pharmaceutical Bulletin · 9
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Studies on prostaglandins. VI. Synthesis of 16(S)-methyl-20-methoxy-PGE2 (YPG-209) having oral bronchodilator activity and its analogs.
1980 · HIDENORI IWAMOTO, NORIYOSHI INUKAI, et al. · Chemical and Pharmaceutical Bulletin · 9
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Comparison of the Angiotensin II Type 1-Receptor Antagonist YM358 and the Angiotensin-Converting Enzyme Inhibitor Enalapril in Rats With Cardiac Volume Overload
2001 · Tomoko Tokioka-Akagi, Akira Fujimori, et al. · The Japanese Journal of Pharmacology · 8
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Pharmacological profile of YM358, a novel nonpeptide angiotensin AT1 receptor antagonist
1997 · Masayuki Shibasaki, Akira Fujimori, et al. · European Journal of Pharmacology · 8
Works count: 57
Citation count: 545
H-index: 13
I10-index: 21
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