Get started
Author

Yasuchika Yamaguchi

Structure-based design of aliskiren, a novel orally effective renin inhibitor
2003 · Jeanette M Wood, Jürgen Maibaum, et al. · Biochemical and Biophysical Research Communications · 506
Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor.
1998 · L Criscione, P Rigollier, et al. · Journal of Clinical Investigation · 226
PDF
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides
2019 · Naoya Shindo, Hirokazu Fuchida, et al. · Nature Chemical Biology · 135
The Mechanism of Action of Inhibitors of Bacterial Two-component Signal Transduction Systems
2000 · Keith Stephenson, Yasuchika Yamaguchi, et al. · Journal of Biological Chemistry · 107
Structural Modification of the P2‘ Position of 2,7-Dialkyl-Substituted 5( S )-Amino-4( S )-hydroxy-8-phenyl-octanecarboxamides: The Discovery of Aliskiren, a Potent Nonpeptide Human Renin Inhibitor Active after Once Daily Dosing in Marmosets
2007 · Jürgen Maibaum, Stefan Stutz, et al. · Journal of Medicinal Chemistry · 95
Improving frequency of thrombosis by altering blood flow in the carrageenan-induced rat tail thrombosis model
2009 · Masayori Hagimori, Seitaro Kamiya, et al. · Pharmacological Research · 53
Design, synthesis and SAR of a series of 2-substituted 4-amino-quinazoline neuropeptide Y Y5 receptor antagonists
2000 · Heinrich Rueeger, Pascal Rigollier, et al. · Bioorganic & Medicinal Chemistry Letters · 47
Novel ring transfer reaction of furans via intramolecular Diels-Alder reaction of allene intermediate: a new double annulation reaction
1985 · Kenji Hayakawa, Yasuchika Yamaguchi, et al. · Tetrahedron Letters · 47
Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth
2016 · Kofi D. Kwofie, Nguyen Huu Tung, et al. · Antimicrobial Agents and Chemotherapy · 42
New generation and intramolecular Diels-Alder reaction of isobenzofurans: an efficient furan ring-transfer reaction and a synthetic entry into the polycyclic ring systems
1987 · Yasuchika Yamaguchi, Hiromi Yamada, et al. · The Journal of Organic Chemistry · 41
Fluorescence ON/OFF switching Zn2+ sensor based on pyridine–pyridone scaffold
2013 · Masayori Hagimori, Takuhiro Uto, et al. · Sensors and Actuators B Chemical · 40
New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth.
2015 · Mitsuko Suzuki, Nguyen Huu Tung, et al. · Bioorganic & Medicinal Chemistry Letters · 36
A high-affinity fluorescent Zn2+ sensor improved by the suppression of pyridine-pyridone tautomerism and its application in living cells
2015 · Masayori Hagimori, Takashi Temma, et al. · Sensors and Actuators B Chemical · 31
Chirality transfer from the furan ring transfer reaction
1989 · Yasuchika Yamaguchi, Noriaki Tatsuta, et al. · Journal of the Chemical Society Chemical Communications · 27
A novel synthesis of sulfamoyl nucleosides
1994 · Haukur Kristinsson, Kurt Nebel, et al. · Tetrahedron · 25
A facile route to vinyl isocyanides
1989 · Jack E. Baldwin, Yasuchika Yamaguchi · Tetrahedron Letters · 24
The P1 N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin
2009 · Yasuchika Yamaguchi, Keith Menear, et al. · Bioorganic & Medicinal Chemistry Letters · 23
An efficient furan ring transfer reaction: a versatile key intermediate leading to the basic skeleton of naturally occurring fused furans
1987 · Yasuchika Yamaguchi, Kenji Hayakawa, et al. · Journal of the Chemical Society Chemical Communications · 22
Anti-Trypanosomal Activity of Diarylheptanoids Isolated from the Bark ofAlnus japonica
2014 · Nguyen Huu Tung, Mitsuko Suzuki, et al. · The American Journal of Chinese Medicine · 18
Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists
2004 · Heinrich Rueeger, Marc Gerspacher, et al. · Bioorganic & Medicinal Chemistry Letters · 18
4,5,6,7-Tetrahydroisobenzofuran-5-one as a Versatile Building Block Leading to the Basic Skeleton of Naturally Occurring Fused Furans
1990 · Ken Kanematsu, Yasuchika Yamaguchi, et al. · Heterocycles · 18
A novel small molecule fluorescent sensor for Zn2+ based on pyridine–pyridone scaffold
2010 · Masayori Hagimori, Naoko Mizuyama, et al. · Talanta · 17
Establishment of a quantitative and qualitative analysis and isolation method for tetracyclic iridoids from Morinda lucida Bentham leaves
2018 · Tomoe Ohta, Tanatorn Tilkanont, et al. · Journal of Pharmaceutical and Biomedical Analysis · 9
Herbicidally Active Sulfamoyl Nucleosides
1995 · Haukur Kristinsson, Kurt Nebel, et al. · ACS symposium series · 8
Synthesis of Fluorescent Pyrrolo[3,4-b]quinolizine Derivatives and Evaluation as a Protein-Labeling Probe
2011 · Yoshinori Tominaga, Masayori Hagimori, et al. · Heterocycles · 7
Works count: 36
Citation count: 1,630
H-index: 18
I10-index: 22
Year
Topic
Type