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Ru Shen

Antitumor Activity of HKI-272, an Orally Active, Irreversible Inhibitor of the HER-2 Tyrosine Kinase
2004 · Sridhar K. Rabindran, Carolyn M. Discafani, et al. · Cancer Research · 642
Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity
2005 · Hwei-Ru Tsou, Elsebe G. Overbeek-Klumpers, et al. · Journal of Medicinal Chemistry · 302
6-Substituted-4-(3-bromophenylamino)quinazolines as Putative Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor (HER-2) Tyrosine Kinases with Enhanced Antitumor Activity
2001 · Hwei-Ru Tsou, Nellie Mamuya, et al. · Journal of Medicinal Chemistry · 275
Synthesis and Structure−Activity Relationships of 6,7-Disubstituted 4-Anilinoquinoline-3-carbonitriles. The Design of an Orally Active, Irreversible Inhibitor of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor (EGFR) and the Human Epidermal Growth Factor Receptor-2 (HER-2)
2002 · Allan Wissner, Elsebe Overbeek, et al. · Journal of Medicinal Chemistry · 270
4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile Inhibitors of Epidermal Growth Factor Receptor Kinase and Their Bioisosteric Relationship to the 4-Anilino-6,7-dialkoxyquinazoline Inhibitors
2000 · Allan Wissner, Dan M. Berger, et al. · Journal of Medicinal Chemistry · 211
Improved immobilization of biomolecules to quinone-rich polydopamine for efficient surface functionalization
2013 · Rifang Luo, Linlin Tang, et al. · Colloids and Surfaces B Biointerfaces · 184
Depression-like phenotype following chronic CB1 receptor antagonism
2010 · Chad E. Beyer, Jason M. Dwyer, et al. · Neurobiology of Disease · 160
Mussel-Inspired One-Step Adherent Coating Rich in Amine Groups for Covalent Immobilization of Heparin: Hemocompatibility, Growth Behaviors of Vascular Cells, and Tissue Response
2014 · Ying Yang, Pengkai Qi, et al. · ACS Applied Materials & Interfaces · 130
Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with In Vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785)
1999 · Carolyn M. Discafani, Marion L. Carroll, et al. · Biochemical Pharmacology · 112
Poly-dopamine, poly-levodopa, and poly-norepinephrine coatings: Comparison of physico-chemical and biological properties with focus on the application for blood-contacting devices
2020 · Xing Tan, Peng Gao, et al. · Bioactive Materials · 89
Polydopamine Modified TiO 2 Nanotube Arrays for Long-Term Controlled Elution of Bivalirudin and Improved Hemocompatibility
2017 · Ying Yang, Xiangyang Li, et al. · ACS Applied Materials & Interfaces · 68
Syntheses and EGFR and HER-2 kinase inhibitory activities of 4-anilinoquinoline-3-carbonitriles: analogues of three important 4-anilinoquinazolines currently undergoing clinical evaluation as therapeutic antitumor agents
2002 · Allan Wissner, M. Brawner Floyd, et al. · Bioorganic & Medicinal Chemistry Letters · 62
Epigallocatechin gallate (EGCG) induced chemical conversion coatings for corrosion protection of biomedical MgZnMn alloys
2015 · Hao Zhang, Rifang Luo, et al. · Corrosion Science · 61
An in vitro evaluation of inflammation response of titanium functionalized with heparin/fibronectin complex
2011 · Guicai Li, Ping Yang, et al. · Cytokine · 57
A novel thixotropic magnesium phosphate-based bioink with excellent printability for application in 3D printing
2018 · You Chen, Yihan Wang, et al. · Journal of Materials Chemistry B · 47
SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis
2022 · Chunying Song, Dong Liu, et al. · Scientific Reports · 43
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Synergistic effects of ammonium polyphosphate and red phosphorus with expandable graphite on flammability and thermal properties of HDPE/EVA blends
2015 · Mengqi Tang, Fei Qi, et al. · Polymers for Advanced Technologies · 43
Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin’s Lymphoma
2018 · Biao Lu, Xiaodong Shen, et al. · ACS Medicinal Chemistry Letters · 40
Validation of an Atomic Absorption Rubidium Ion Efflux Assay for KCNQ/M-Channels Using the Ion Channel Reader 8000
2004 · Kewei Wang, Beal Mcilvain, et al. · Assay and Drug Development Technologies · 35
Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways
2022 · Yu Zhou, Xin Li, et al. · Frontiers in Immunology · 32
Hemocompatibility of lanthanum oxide films fabricated by dual plasma deposition
2006 · F.J. Jing, L. Wang, et al. · Thin Solid Films · 31
A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer
2021 · Suxing Liu, Di Li, et al. · OncoTargets and Therapy · 30
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Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis
2021 · Suxing Liu, Dong Liu, et al. · Scientific Reports · 30
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Facile immobilization of vascular endothelial growth factor on a tannic acid-functionalized plasma-polymerized allylamine coating rich in quinone groups
2016 · Kaiqin Xiong, Pengkai Qi, et al. · RSC Advances · 29
Formation of rod-shaped wear debris and the graphitization tendency of Cu-doped hydrogenated diamond-like carbon films
2019 · Y.L. Gong, P.P. Jing, et al. · Diamond and Related Materials · 27
Works count: 53
Citation count: 3,217
H-index: 25
I10-index: 36
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