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Katherine M. Welsh

Observed names: K M Welsh, K. M. WELSH, K. M. Welsh, K. Welsh, K.M. Welsh, Katherine Welsh
OpenAlex ID: A5110851807
Multiple protein-aspartate phosphatases provide a mechanism for the integration of diverse signals in the control of development in B. subtilis
1994 · Marta Perego, Conrad Hanstein, et al. · Cell · 296
Ionomycin-activated Calpain Triggers Apoptosis
2002 · Shirley Gil-Parrado, Amaury Fernández-Montalván, et al. · Journal of Biological Chemistry · 222
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Structure of and kinetic channelling in bifunctional dihydrofolate reductase–thymidylate synthase
1994 · Daniel R. Knighton, Chen-Chen Kan, et al. · Nature Structural Biology · 198
Design of thymidylate synthase inhibitors using protein crystal structures: the synthesis and biological evaluation of a novel class of 5-substituted quinazolinones
1993 · Stephen E. Webber, Ted M. Bleckman, et al. · Journal of Medicinal Chemistry · 162
Crystal-structure-based design and synthesis of benz[cd]indole-containing inhibitors of thymidylate synthase
1992 · Michael D. Varney, Gifford P. Marzoni, et al. · Journal of Medicinal Chemistry · 116
Stereochemical mechanism of action for thymidylate synthase based on the X-ray structure of the covalent inhibitory ternary complex with 5-fluoro-2′-deoxyuridylate and 5,10-methylenetetrahydrofolate
1990 · D.A. Matthews, J.E. Villafranca, et al. · Journal of Molecular Biology · 116
Biochemical characterization of the essential GTP-binding protein Obg of Bacillus subtilis
1994 · K M Welsh, K A Trach, et al. · Journal of Bacteriology · 79
Thermodynamics, kinetics, and mechanism in yeast inorganic pyrophosphatase catalysis of inorganic pyrophosphate:inorganic phosphate equilibration
1981 · B. Springs, K. M. Welsh, et al. · Biochemistry · 69
Transition-state structure in the yeast alcohol dehydrogenase reaction: the magnitude of solvent and .alpha.-secondary hydrogen isotope effects
1980 · Katherine M. Welsh, Donald J. Creighton, et al. · Biochemistry · 64
Design and synthesis of novel 6,7-imidazotetrahydroquinoline inhibitors of thymidylate synthase using iterative protein crystal structure analysis
1992 · Siegfried H. Reich, Mary Ann M. Fuhry, et al. · Journal of Medicinal Chemistry · 61
Catalytic specificity of yeast inorganic pyrophosphatase for magnesium ion as cofactor. An analysis of divalent metal ion and solvent isotope effects on enzyme function
1983 · Katherine M. Welsh, Andrew Jacobyansky, et al. · Biochemistry · 50
The zinc content of yeast alcohol dehydrogenase
1976 · Judith P. Klinman, Katherine Welsh · Biochemical and Biophysical Research Communications · 42
Synthesis and Biological Evaluation of Novel 2,6-Diaminobenz[cd]indole Inhibitors of Thymidylate Synthase Using the Protein Structure as a Guide
1995 · Michael D. Varney, Cindy L. Palmer, et al. · Journal of Medicinal Chemistry · 33
Evidence that catalysis by yeast inorganic pyrophosphatase proceeds by direct phosphoryl transfer to water and not via a phosphoryl enzyme intermediate
1984 · Marcel A. Gonzalez, Martin R. Webb, et al. · Biochemistry · 29
Yeast inorganic pyrophosphatase. Functional and cadmium-113 ion and phosphorus-31 nuclear magnetic resonance studies of the cadmium(+2)-enzyme
1983 · Katherine M. Welsh, Ian M. Armitage, et al. · Biochemistry · 24
Yeast inorganic pyrophosphatase. A model for active-site structure based on cadmium-113 and phosphorus-31 NMR studies
1984 · Katherine M. Welsh, Barry S. Cooperman · Biochemistry · 23
Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase
1992 · M. Rami Reddy, Russell J. Bacquet, et al. · Journal of the American Chemical Society · 18
Characterization of membrane-bound nicotinamide adenine dinucleotide glycohydrolase of Vibrio cholerae.
1979 · P.B. Fernandes, K.M. Welsh, et al. · Journal of Biological Chemistry · 14
Epoxide inhibition of alcohol dehydrogenases. Identification of modified cysteines in yeast alcohol dehydrogenase and demonstration of reversible and irreversible inhibition of liver alcohol dehydrogenase by styrene oxide
1977 · Judith P. Klinman, Katherine M. Welsh, et al. · Biochemistry · 13
ChemInform Abstract: Structure‐Based Design of Lipophilic Quinazoline Inhibitors of Thymidylate Synthase (TS).
1996 · T. R. JONES, M. D. VARNEY, et al. · ChemInform · 4
ChemInform Abstract: Novel Angular Tricyclic Inhibitors of Thymidylate Synthase.
1993 · S. H. REICH, NGUYEN DZUY NGUYEN DZUY, et al. · ChemInform · 1
Solvent Isotope Effects in the Yeast Alcohol Dehydrogenase Reaction
1977 · Judith P. Klinman, Katherine M. Welsh, et al. · Elsevier eBooks · 1
427 POSTER Preclinical development of xiapuradamib therapy for lung cancer
2006 · E. Dean, M. Ranson, et al. · European Journal of Cancer Supplements
ChemInform Abstract: Structure‐Based Design of Substituted Diphenyl Sulfones and Sulfoxides as Lipophilic Inhibitors of Thymidylate Synthase.
1997 · T. R. JONES, S. E. WEBBER, et al. · ChemInform
Works count: 24
Citation count: 1,635
H-index: 17
I10-index: 19
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