Get started
Author

Hazem A. Mahdy

Observed names: H. A. Mahdy, Hazem A Mahdy, Hazem Mahdy, Hazem.A. Mahdy, Mahdy, Hazem A.
Institution: Al-Azhar University
ORCID: 0000-0002-6620-241X
Observed ORCID: 0000-0002-6620-241X
OpenAlex ID: A5111042471
Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers
2019 · Hazem A. Mahdy, Mohammed K. Ibrahim, et al. · Bioorganic Chemistry · 178
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies
2021 · Hazem Elkady, Alaa Elwan, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 131
Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents
2021 · Souad A. El-Metwally, Mohsen M. Abou-El-Regal, et al. · Bioorganic Chemistry · 129
Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFR WT and EGFR T790M
2020 · Ahmed A. Nasser, Ibrahim H. Eissa, et al. · Organic & Biomolecular Chemistry · 126
New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis
2021 · Nawaf A. Alsaif, Mohammed A. Dahab, et al. · Bioorganic Chemistry · 114
Design, molecular docking, in vitro, and in vivo studies of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors with potential activity against hepatocellular carcinoma
2020 · Ibrahim.H. Eissa, Mohammed K. Ibrahim, et al. · Bioorganic Chemistry · 103
New bis([1,2,4]triazolo)[4,3-a:3′,4′-c]quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer evaluation
2021 · Mohammed M. Alanazi, Hazem A. Mahdy, et al. · Bioorganic Chemistry · 100
Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors
2020 · Khaled El-Adl, Abdel-Ghany A. El-Helby, et al. · Bioorganic & Medicinal Chemistry · 100
Discovery of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation
2020 · Ibrahim H. Eissa, Abdel-Ghany A. El-Helby, et al. · Bioorganic Chemistry · 89
New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies
2022 · Eslam B. Elkaeed, Mohammed S. Taghour, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 80
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors
2019 · Ibrahim H. Eissa, Ahmed M. Metwaly, et al. · Archiv der Pharmazie · 78
Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies
2021 · Mohamed M. Khalifa, Ahmed A. Al-Karmalawy, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 76
Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors
2020 · Abdel-Ghany A. El-Helby, Helmy Sakr, et al. · Bioorganic Chemistry · 74
Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation
2022 · Alaa Elwan, Abdallah E. Abdallah, et al. · Molecules · 62
PDF
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation
2022 · Mohammed S. Taghour, Hazem A. Mahdy, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 61
Design, synthesis, molecular docking, anticancer evaluations, and in silico pharmacokinetic studies of novel 5‐[(4‐chloro/2,4‐dichloro)benzylidene]thiazolidine‐2,4‐dione derivatives as VEGFR‐2 inhibitors
2020 · Khaled El‐Adl, Abdel‐Ghany A. El‐Helby, et al. · Archiv der Pharmazie · 58
Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies
2021 · Nawaf A. Alsaif, Mohammed S. Taghour, et al. · Bioorganic & Medicinal Chemistry · 40
Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers
2023 · Abdulrahman M. Saleh, Hazem A. Mahdy, et al. · RSC Advances · 39
PDF
Rationale design and synthesis of new apoptotic thiadiazole derivatives targeting VEGFR-2: computational and in vitro studies
2023 · Walid E. Elgammal, Hazem Elkady, et al. · RSC Advances · 35
PDF
Targeting VEGFR‐2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies
2021 · Nawaf A. Alsaif, Hazem A. Mahdy, et al. · Archiv der Pharmazie · 33
New Theobromine Derivatives Inhibiting VEGFR-2: Design, Synthesis, Antiproliferative, Docking and Molecular Dynamics Simulations
2023 · Hazem A Mahdy, Hazem Elkady, et al. · Future Medicinal Chemistry · 31
Screening of Some Sulfonamide and Sulfonylurea Derivatives as Anti-Alzheimer’s Agents Targeting BACE1 and PPARγ
2020 · Ning Li, Yan Wang, et al. · Journal of Chemistry · 29
PDF
Design, synthesis, in vitro, and in silico studies of new thiadiazol derivatives as promising VEGFR-2 inhibitors and apoptosis inducers
2024 · Hazem A. Mahdy, Hazem Elkady, et al. · Journal of Molecular Structure · 27
Design, synthesis, and evaluation of novel thiadiazole derivatives as potent VEGFR-2 inhibitors: a comprehensive in vitro and in silico study
2024 · Ibrahim H. Eissa, Walid E. Elgammal, et al. · RSC Advances · 27
PDF
Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase
2021 · Nawaf A. Alsaif, Alaa Elwan, et al. · Molecular Diversity · 27
Works count: 73
Citation count: 2,236
H-index: 26
I10-index: 41
Year
Topic
Type