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Yahao Bu

Observed names: Y. Bu, YAHAO BU
OpenAlex ID: A5111537798
Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361)
2018 · Michael P. Smolinski, Yahao Bu, et al. · Journal of Medicinal Chemistry · 99
SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway
2009 · Bing Su, Yahao Bu, et al. · Journal of Biological Chemistry · 84
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Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations
2021 · Sameer Urgaonkar, Kamil Nosol, et al. · Journal of Medicinal Chemistry · 74
SSeCKS Metastasis-Suppressing Activity in MatLyLu Prostate Cancer Cells Correlates with Vascular Endothelial Growth Factor Inhibition
2006 · Bing Su, Qiao Zheng, et al. · Cancer Research · 73
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Thiazolyl N-benzyl-substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities
2011 · Asal Fallah-Tafti, Alireza Foroumadi, et al. · European Journal of Medicinal Chemistry · 66
Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion
2009 · Sanjay Sachdev, Yahao Bu, et al. · BMC Cancer · 57
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Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2012 · Muralidharan Anbalagan, Alaa Ali, et al. · Molecular Cancer Therapeutics · 47
v-Src-mediated Down-regulation of SSeCKS Metastasis Suppressor Gene Promoter by the Recruitment of HDAC1 into a USF1-Sp1-Sp3 Complex
2007 · Yahao Bu, Irwin H. Gelman · Journal of Biological Chemistry · 39
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An ion-current-based, comprehensive and reproducible proteomic strategy for comparative characterization of the cellular responses to novel anti-cancer agents in a prostate cell model
2012 · Chengjian Tu, Jun Li, et al. · Journal of Proteomics · 31
Role for transcription factor TFII‐I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src
2010 · Yahao Bu, Lingqiu Gao, et al. · International Journal of Cancer · 20
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KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
2018 · Michael J. Ciesielski, Yahao Bu, et al. · Journal of Neuro-Oncology · 15
465 Tirbanibulin, a novel anti-proliferative and pro-apoptotic agent for the treatment of actinic keratosis
2021 · L. Pitzonka, M. Cutler, et al. · Journal of Investigative Dermatology · 5
Ion Current-Based Proteomic Profiling for Understanding the Inhibitory Effect of Tumor Necrosis Factor Alpha on Myogenic Differentiation
2016 · Chengjian Tu, Yahao Bu, et al. · Journal of Proteome Research · 5
Abstract 2487: Mechanism of action KX01 (KX2-391), a novel tubulin polymerization and Src signaling inhibitor proceeding to Phase II clinical trials
2010 · YAHAO BU, Michael Smolinski, et al. · Cancer Research · 3
Supplementary Table 1 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
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Supplementary Figure Legend from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
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Supplementary Figure 1 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
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Supplementary Figure 2 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
Supplementary Figure 5 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
Supplementary Methods from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
Supplementary Figure 3 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
Supplementary Figure 4 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
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Supplementary Figure 3 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
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Data from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
2023 · Muralidharan Anbalagan, Alaa Ali, et al.
Abstract 4717: Effective preclinical management of angiosarcoma with oral paclitaxel
2019 · Murray J. Cutler, Krista E. Belko, et al. · Cancer Research
Works count: 28
Citation count: 618
H-index: 11
I10-index: 11
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