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M R Boyd
Observed names:
M Boyd,
M. R. BOYD,
M. R. Boyd,
M.R. Boyd,
Malcolm R. Boyd
Observed institutions:
University College Dublin,
National Institutes of Health,
Georgetown University,
Fairfield Hospital
OpenAlex ID:
A5111611396
Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell culture
1987
·
M R Boyd
, T H Bacon
, et al.
·
Antimicrobial Agents and Chemotherapy
·
240
Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir]
1989
·
R A Vere Hodge
, D Sutton
, et al.
·
Antimicrobial Agents and Chemotherapy
·
208
Penciclovir: a review of its spectrum of activity, selectivity, and cross-resistance pattern
1993
·
M. R. Boyd
, S. Safrin
, et al.
·
Antiviral chemistry & chemotherapy
·
149
The pulmonary clara cell as a target for toxic chemicals requiring metabolic activation; studies with carbon tetrachloride.
1980
·
M R Boyd
, C N Statham
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
116
Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxymethylbut-1-yl) guanine (BRL 39123) in animals
1988
·
M R Boyd
, T H Bacon
, et al.
·
Antimicrobial Agents and Chemotherapy
·
115
In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol.
1978
·
M R Boyd
, L T Burka
·
Journal of Pharmacology and Experimental Therapeutics
·
109
Paradoxical effects of cobaltous chloride and salts of other divalent metals on tissue levels of reduced glutathione and microsomal mixed-function oxidase components.
1978
·
H A Sasame
, M R Boyd
·
Journal of Pharmacology and Experimental Therapeutics
·
101
In vitro antiviral activity of penciclovir, a novel purine nucleoside, against duck hepatitis B virus
1994
·
T Shaw
, P Amor
, et al.
·
Antimicrobial Agents and Chemotherapy
·
100
Penciclovir is a selective inhibitor of hepatitis B virus replication in cultured human hepatoblastoma cells
1996
·
B E Korba
, M R Boyd
·
Antimicrobial Agents and Chemotherapy
·
90
PDF
In vitro studies on the metabolic activation of the pulmonary toxin, 4-ipomeanol, by rat lung and liver microsomes.
1978
·
M R Boyd
, L T Burka
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
89
Acute pulmonary injury in rats by nitrofurantoin and modification by vitamin E, dietary fat, and oxygen.
1979
·
M R Boyd
, G L Catignani
, et al.
·
PubMed
·
80
In vitro metabolic activation of the pulmonary toxin, 4-ipomeanol, in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung.
1982
·
T R Devereux
, K G Jones
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
72
Studies on the mechanism of toxicity and of development of tolerance to the pulmonary toxin, alpha-naphthylthiourea (ANTU).
1976
·
M R Boyd
, R A Neal
·
Drug Metabolism and Disposition
·
72
Pharmacokinetics of doxorubicin in isolated lung of dogs and humans perfused in vivo.
1984
·
R F Minchin
, M R Johnston
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
58
Comparative activity of penciclovir and acyclovir in mice infected intraperitoneally with herpes simplex virus type 1 SC16
1993
·
D Sutton
, M R Boyd
·
Antimicrobial Agents and Chemotherapy
·
57
Activity of penciclovir against Epstein-Barr virus
1995
·
T H Bacon
, M R Boyd
·
Antimicrobial Agents and Chemotherapy
·
41
Synthesis and antiviral activity of 9-alkoxypurines. 2. 9-(2,3-Dihydroxypropoxy)-, 9-(3,4-dihydroxybutoxy)-, and 9-(1,4-dihydroxybut-2-oxy)purines
1991
·
Stuart Bailey
, Michael R. Harnden
, et al.
·
Journal of Medicinal Chemistry
·
35
Renal toxicity due to reactive metabolites formed in situ in the kidney: investigations with 4-ipomeanol in the mouse.
1981
·
M R Boyd
, J S Dutcher
·
Journal of Pharmacology and Experimental Therapeutics
·
33
The in vitro formation of glutathione conjugates with the microsomally activated pulmonary bronchiolar aklylating agent and cytotoxin, 4-ipomeanol.
1980
·
A R Buckpitt
, M R Boyd
·
Journal of Pharmacology and Experimental Therapeutics
·
33
Antiviral Activities and Pharmacokinetics of Penciclovir and Famciclovir in Pekin Ducks Chronically Infected with Duck Hepatitis B Virus
1996
·
K.N. Tsiquaye
, D. Sutton
, et al.
·
Antiviral chemistry & chemotherapy
·
30
Covalent binding of metabolites of 4-ipomeanol to rabbit pulmonary and hepatic microsomal proteins and to the enzymes of the pulmonary cytochrome P-450-dependent monooxygenase system.
1983
·
S R Slaughter
, C N Statham
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
30
Effects of buthionine sulfoximine on the nephrotoxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU).
1985
·
R A Kramer
, H M Schuller
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
28
The activity of iododeoxyuridine, adenine arabinoside, cytosine arabinoside, ribavirin and phosphonoacetic acid against herpes virus in the hairless mouse model
1977
·
S. R. B. Harris
, M. R. Boyd
·
Journal of Antimicrobial Chemotherapy
·
19
Effects of Penciclovir and Famciclovir in a Murine Model of Encephalitis Induced by Intranasal Inoculation of Herpes Simplex Virus Type 1
1992
·
S. E. Goldthorpe
, M. R. Boyd
, et al.
·
Antiviral chemistry & chemotherapy
·
18
PDF
Comparative activity of amantadine and ribavirin against influenza virus in vitro: possible clinical relevance
1983
·
M J Browne
, M Y Moss
, et al.
·
Antimicrobial Agents and Chemotherapy
·
18
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Works count:
43
Citation count:
2,011
H-index:
22
I10-index:
29
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