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Yoshitsugu Adachi

Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
2013 · Youn-Bok Lee, Han-Jou Chen, et al. · Cell Reports · 496
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Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
2013 · Danielle C. Diaper, Yoshitsugu Adachi, et al. · Human Molecular Genetics · 160
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A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration
2018 · Daniel A Solomon, Alan Stepto, et al. · Brain · 100
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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
2017 · Youn-Bok Lee, Pranetha Baskaran, et al. · Human Molecular Genetics · 90
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Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD
2013 · Danielle C. Diaper, Yoshitsugu Adachi, et al. · Human Molecular Genetics · 81
TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila
2013 · Lies Vanden Broeck, Marina Naval-Sánchez, et al. · Cell Reports · 65
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A conserved nuclear receptor, Tailless, is required for efficient proliferation and prolonged maintenance of mushroom body progenitors in the Drosophila brain
2008 · Mitsuhiko Kurusu, Yasushi Maruyama, et al. · Developmental Biology · 52
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Conserved cis-regulatory modules mediate complex neural expression patterns of the eyeless gene in the Drosophila brain
2003 · Yoshitsugu Adachi, Bernd Hauck, et al. · Mechanisms of Development · 52
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Cross-regulatory protein–protein interactions between Hox and Pax transcription factors
2008 · Serge Plaza, Frederic Prince, et al. · Proceedings of the National Academy of Sciences · 51
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Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila
2012 · Dimitrios K. Papadopoulos, Kassiani Skouloudaki, et al. · Developmental Biology · 29
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Function and specificity of synthetic Hox transcription factors in vivo
2010 · Dimitrios K. Papadopoulos, Vladana Vukojević, et al. · Proceedings of the National Academy of Sciences · 26
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Brain patterning defects caused by mutations of thetwin of eyelessgene inDrosophila melanogaster
2009 · Katsuo Furukubo-Tokunaga, Yoshitsugu Adachi, et al. · Fly · 22
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A lineage-related reciprocal inhibition circuitry for sensory-motor action selection
2017 · Benjamin Kottler, Vincenzo G. Fiore, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 14
Cross-phylum regulatory potential of the ascidian Otx gene in brain development in Drosophila melanogaster
2001 · Yoshitsugu Adachi, Tomoko Nagao, et al. · Development Genes and Evolution · 11
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Expanded G4C2 repeats linked to C9ORF72ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic
2013 · Youn-Bok Lee, Han-Jou Chen, et al. · Molecular Neurodegeneration · 7
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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
2020 · Youn-Bok Lee, Pranetha Baskaran, et al. · Human Molecular Genetics · 3
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P2‐134: TDP‐43 neurotoxicity is caused by a failure of steroid receptor–dependent transcriptional program switching in Drosophila
2012 · Bart Dermaut, Lies Vanden Broeck, et al. · Alzheimer s & Dementia
Drosophila models of TDP-43 proteinopathy
2010 · Yoshitsugu Adachi, Danielle C. Diaper, et al. · Research Portal (King's College London)
TDP-43 in motor neuron disease formation in Drosophila
2010 · Danielle C. Diaper, Yoshitsugu Adachi, et al. · Research Portal (King's College London)
Cross-phylum functional equivalence of Otx genes and the origin of brain patterning
2007 · Yoshitsugu Adachi
Works count: 22
Citation count: 1,258
H-index: 13
I10-index: 14
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