Author

Gregory N. Dietsch

Observed names: Dietsch, Gregory N., G N Dietsch, Gregory Dietsch, Gregory N Dietsch

Observed institutions: Cincinnati Children's Hospital Medical Center, Johns Hopkins University, Eli Lilly (United States), University of Washington, University of Michigan, Johns Hopkins Medicine, Providence Portland Medical Center, Portland VA Medical Center, Seattle Foundation, Michigan Medicine, Evanston Hospital, Achieve Life Sciences (Canada), 3D Medicines, Inc. (China)

OpenAlex ID: A5111630399

Chemokine expression in murine experimental allergic encephalomyelitis

1995 · Ronald Godiska, David Chantry, et al. · Journal of Neuroimmunology · 353

VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC

2011 · Hailing Lu, Gregory N. Dietsch, et al. · Clinical Cancer Research · 180

The Role of Recombinant Platelet-Activating Factor Acetylhydrolase in a Neonatal Rat Model of Necrotizing Enterocolitis

1997 · Michael S Caplan, Matthew Lickerman, et al. · Pediatric Research · 130

Phase Ib Trial of the Toll-like Receptor 8 Agonist, Motolimod (VTX-2337), Combined with Cetuximab in Patients with Recurrent or Metastatic SCCHN

2016 · Laura Q.M. Chow, Chihiro Morishima, et al. · Clinical Cancer Research · 127

Effect of Adding Motolimod to Standard Combination Chemotherapy and Cetuximab Treatment of Patients With Squamous Cell Carcinoma of the Head and Neck

2018 · Robert L. Ferris, Nabil F. Saba, et al. · JAMA Oncology · 113

PDF

Inhibition of Experimental Vasospasm With Anti–Intercellular Adhesion Molecule-1 Monoclonal Antibody in Rats

1997 · Eric M. Oshiro, Patricia A. Hoffman, et al. · Stroke · 92

Prevention of cerebral vasospasm by a humanized anti-CD11/CD18 monoclonal antibody administered after experimental subarachnoid hemorrhage in nonhuman primates

2003 · Richard E. Clatterbuck, Philippe Gailloud, et al. · Journal of neurosurgery · 80

Recombinant Human Platelet-Activating Factor- Acetylhydrolase Inhibits Airway Inflammation and Hyperreactivity in Mouse Asthma Model

2000 · William R Henderson, Jiangyang Lu, et al. · The Journal of Immunology · 77

PDF

TLR8 stimulation enhances cetuximab-mediated natural killer cell lysis of head and neck cancer cells and dendritic cell cross-priming of EGFR-specific CD8+ T cells

2013 · Ryan M. Stephenson, Chwee Ming Lim, et al. · Cancer Immunology Immunotherapy · 70

Coordinated Activation of Toll-Like Receptor8 (TLR8) and NLRP3 by the TLR8 Agonist, VTX-2337, Ignites Tumoricidal Natural Killer Cell Activity

2016 · Gregory N. Dietsch, Hailing Lu, et al. · PLoS ONE · 67

PDF

A Phase I Dose-Finding Study of the Novel Toll-like Receptor 8 Agonist VTX-2337 in Adult Subjects with Advanced Solid Tumors or Lymphoma

2014 · Donald W. Northfelt, Ramesh K. Ramanathan, et al. · Clinical Cancer Research · 66

The Ultra-Potent and Selective TLR8 Agonist VTX-294 Activates Human Newborn and Adult Leukocytes

2013 · David J. Dowling, Zhen Tan, et al. · PLoS ONE · 66

PDF

Prevention of vasospasm by anti-CD11/CD18 monoclonal antibody therapy following subarachnoid hemorrhage in rabbits

2004 · Gustavo Pradilla, Paul P. Wang, et al. · Journal of neurosurgery · 65

Characterization of the Inflammatory Response to a Highly Selective PDE4 Inhibitor in the Rat and the Identification of Biomarkers that Correlate with Toxicity

2006 · Gregory N. Dietsch, Chris R. Dipalma, et al. · Toxicologic Pathology · 56

Inhibition of vasospasm with lymphocyte function-associated antigen—1 monoclonal antibody in a femoral artery model in rats

2002 · Richard E. Clatterbuck, Eric M. Oshiro, et al. · Journal of neurosurgery · 53

Granzyme B Expression Is Enhanced in Human Monocytes by TLR8 Agonists and Contributes to Antibody-Dependent Cellular Cytotoxicity

2015 · Saranya Elavazhagan, Kavin Fatehchand, et al. · The Journal of Immunology · 44

PDF

Mast cell proteases liberate stable encephalitogenic fragments from intact myelin

1991 · Gregory N. Dietsch, David J. Hinrichs · Cellular Immunology · 43

Late-Stage Cancer Patients Remain Highly Responsive to Immune Activation by the Selective TLR8 Agonist Motolimod (VTX-2337)

2015 · Gregory N. Dietsch, Tressa D. Randall, et al. · Clinical Cancer Research · 37

Requirements for alpha d in IgG immune complex-induced rat lung injury.

1998 · T P Shanley, R L Warner, et al. · PubMed · 30

Requirements for αd in IgG Immune Complex-Induced Rat Lung Injury

1998 · Thomas P Shanley, Roscoe L Warner, et al. · The Journal of Immunology · 26

PDF

TLR8 ligation induces apoptosis of monocytic myeloid-derived suppressor cells

2017 · Yushe Dang, Zina J Rutnam, et al. · Journal of Leukocyte Biology · 25

PDF

MV-626, a potent and selective inhibitor of ENPP1 enhances STING activation and augments T-cell mediated anti-tumor activity in vivo

2018 · Jason R. Baird, Gregory N. Dietsch, et al. · 20

Toll-like Receptor 4 Ligands Down-regulate Fcγ Receptor IIb (FcγRIIb) via MARCH3 Protein-mediated Ubiquitination

2015 · Kavin Fatehchand, Li Ren, et al. · Journal of Biological Chemistry · 20

Motolimod effectively drives immune activation in advanced cancer patients

2016 · Gregory N. Dietsch · OncoImmunology · 11

VTX‐1463, a novel TLR‐8 agonist, attenuates nasal congestion after ragweed challenge in sensitized beagle dogs

2015 · Christopher M. Royer, Karin Rudolph, et al. · Immunity Inflammation and Disease · 7

PDF

Works count: 46

Citation count: 1,859

H-index: 21

I10-index: 24