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Darren A. Plumb

Observed names: D. Plumb, D.A. Plumb, DA Plumb, Darren A Plumb, Darren Plumb, P. Cullerne Darren, Plumb D. A., Plumb, D
Observed institutions: Hospital for Special Surgery, Guy's Hospital, University of Liverpool, King's College London, Cornell University, Breast Cancer Now, Wellcome Centre for Cell-Matrix Research, University of Manchester, PsiOxus Therapeutics (United Kingdom), Weill Cornell Medicine
OpenAlex ID: A5111651215
Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis
2011 · MB Goldring, M Otero, et al. · European Cells and Materials · 499
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PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
2016 · Fara Brasó-Maristany, Simone Filosto, et al. · Nature Medicine · 260
In Vivo Cyclic Compression Causes Cartilage Degeneration and Subchondral Bone Changes in Mouse Tibiae
2013 · Frank C. Ko, Cecilia Dragomir, et al. · Arthritis & Rheumatism · 162
A Novel and Highly Conserved Collagen (proα1(XXVII)) with a Unique Expression Pattern and Unusual Molecular Characteristics Establishes a New Clade within the Vertebrate Fibrillar Collagen Family
2003 · Raymond P. Boot-Handford, Danny S. Tuckwell, et al. · Journal of Biological Chemistry · 152
E74-like Factor 3 (ELF3) Impacts on Matrix Metalloproteinase 13 (MMP13) Transcriptional Control in Articular Chondrocytes under Proinflammatory Stress
2011 · Miguel Otero, Darren A. Plumb, et al. · Journal of Biological Chemistry · 96
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Mouse Models of Osteoarthritis: Surgical Model of Posttraumatic Osteoarthritis Induced by Destabilization of the Medial Meniscus
2014 · Kirsty L. Culley, Cecilia L. Dragomir, et al. · Methods in molecular biology · 92
Collagen XXVII Is Developmentally Regulated and Forms Thin Fibrillar Structures Distinct from Those of Classical Vertebrate Fibrillar Collagens
2007 · Darren A. Plumb, Vivek Dhir, et al. · Journal of Biological Chemistry · 77
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Human Chondrocyte Cultures as Models of Cartilage-Specific Gene Regulation
2011 · Miguel Otero, Marta Favero, et al. · Methods in molecular biology · 72
ADAM17 Controls Endochondral Ossification by Regulating Terminal Differentiation of Chondrocytes
2013 · Katherine C. Hall, Daniel Hill, et al. · Molecular and Cellular Biology · 62
Collagen XXVII Organises the Pericellular Matrix in the Growth Plate
2011 · Darren A. Plumb, Laila Ferrara, et al. · PLoS ONE · 59
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GADD45β Enhances Col10a1 Transcription via the MTK1/MKK3/6/p38 Axis and Activation of C/EBPβ-TAD4 in Terminally Differentiating Chondrocytes
2010 · Kaneyuki Tsuchimochi, Miguel Otero, et al. · Journal of Biological Chemistry · 49
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Progressive cell‐mediated changes in articular cartilage and bone in mice are initiated by a single session of controlled cyclic compressive loading
2016 · Frank C. Ko, Cecilia L. Dragomir, et al. · Journal of Orthopaedic Research® · 41
Elf3 Contributes to Cartilage Degradation in vivo in a Surgical Model of Post-Traumatic Osteoarthritis
2018 · Elisabeth B. Wondimu, Kirsty L. Culley, et al. · Scientific Reports · 36
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Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity
2016 · Blandine Poulet, Ke Liu, et al. · PLoS ONE · 27
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Abstract 5013: NG-641: An oncolytic T-SIGn virus targeting cancer-associated fibroblasts in the stromal microenvironment of human carcinomas
2019 · Brian R. Champion, Matthieu Besneux, et al. · Cancer Research · 11
Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
2017 · Fara Brasó-Maristany, Simone Filosto, et al. · Nature Medicine · 3
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Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
2017 · Fara Brasó-Maristany, Simone Filosto, et al. · Nature Medicine · 3
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Roles of inflammatory and anabolic cytokines in cartilage metabolism
2010 · Mary B. Goldring, Miguel Otero, et al. · European Cells and Materials · 3
ELF3 contributes to cartilage degradation by controlling the expression of MMP13 in vivo, in a surgical model of osteoarthritis in mice
2016 · E.B. Wondimu, K.L. Culley, et al. · Osteoarthritis and Cartilage · 1
The E74-like factor 3 (ELF3) is a central mediator of cartilage degradation in a surgically-induced osteoarthritis model in mice
2015 · E.B. Wondimu, K.L. Culley, et al. · Osteoarthritis and Cartilage · 1
Abstract 5746: Flexible tumor-specific cytokine and antigen delivery through the T-SIGn vector platform enables effective CAR-T cell therapy against solid tumors
2023 · Maria Stella Sasso, Rachel Bergin, et al. · Cancer Research
Accelerated cartilage degradation and increased chondrocyte apoptosis in GADD45β knockout mice subjected to a surgical model of OA
2016 · D.A. Plumb, C.L. Dragomir, et al. · Osteoarthritis and Cartilage
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Col2a1-driven TIMP3 disrupts endochondral growth and compromises bone structure and integrity: persistent transgene function in the chondrocyte-to-osteoblast lineage
2016 · B. Poulet, K Liu, et al.
Chondrocyte-specific Timp3 Overexpression Disrupts Endochondral Growth and Compromises Bone Structure and Integrity: Functional Impact of the Chondrocyte-to-osteoblast Lineage
2016 · Poulet, B, Liu, K, et al. · RVC Research Online (Royal Veterinary College)
217 Mechanisms of Action of Ese1, a Novel Transcriptional Regulator of Cartilage Remodeling, in Mmp-13 Regulation
2010 · E. Olivotto, M. Otero, et al. · Osteoarthritis and Cartilage
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Works count: 33
Citation count: 1,706
H-index: 14
I10-index: 15
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