Author

Darrell E. O'Brien

Observed names: Darrell E. O'brien, Darrell O'Brien

Observed institutions: MRIGlobal, University of Missouri–Kansas City

OpenAlex ID: A5111708977

Purine analog inhibitors of xanthine oxidase ‐ structure activity relationships and proposed binding of the molybdenum cofactor

1985 · Roland K. Robins, Ganapathi R. Revankar, et al. · Journal of Heterocyclic Chemistry · 104

3-Substituted 5,7-dimethylpyrazolo[1,5-a]pyrimidines, 3',5'-cyclic AMP phosphodiesterase inhibitors

1974 · Thomas Novinson, Ruth Hanson, et al. · Journal of Medicinal Chemistry · 73

Synthesis and antitrichomonal activity of certain pyrazolo[1,5-a]pyrimidines

1975 · Keitaro Senga, Thomas Novinson, et al. · Journal of Medicinal Chemistry · 43

The synthesis and chemical reactions of certain pyrazolo[1,5‐a]‐1,3,5‐triazines

1974 · Jože Kobe, Roland K. Robins, et al. · Journal of Heterocyclic Chemistry · 40

Adenosine cyclic 3',5'-monophosphate phosphodiesterase inhibitors. 2. 3-Substituted 5,7-dialkylpyrazolo[1,5-a]pyrimidines

1975 · Thomas Novinson, Jon P. Miller, et al. · Journal of Medicinal Chemistry · 38

Studies on Methylglyoxal Bis(guanylhydrazone)1 Analogs. II. Structural Variations on Methylglyoxal Bis(guanylhydrazone)2

1963 · Fred Baiocchi, C. C. Cheng, et al. · Journal of Medicinal Chemistry · 35

Synthesis and enzymic activity of some novel xanthine oxidase inhibitors. 3-Substituted 5,7-dihydroxypyrazolo[1,5-a]pyrimidines

1976 · Robert H. Springer, Mary K. Dimmitt, et al. · Journal of Medicinal Chemistry · 34

Potential Purine Antagonists. XIX. Synthesis of Some 9-Alkyl(aryl)-2-amino-6-substituted Purines and Related V-Triazolo [d]pyrimidines1

1959 · Henry C. Koppel, Darrell E. O'Brien, et al. · Journal of the American Chemical Society · 32

Synthesis and enzymic activity of various substituted pyrazolo[1,5-a]-1,3,5-triazines as adenosine cyclic 3',5'-phosphate phosphodiesterase inhibitors

1982 · Keitaro Senga, Darrell E. O'Brien, et al. · Journal of Medicinal Chemistry · 31

Synthesis and enzymic activity of 6-carbethoxy- and 6-ethoxy-3,7-disubstituted pyrazolo[1,5-a]pyrimidines and related derivatives as adenosine cyclic 3',5'-phosphate phosphodiesterase inhibitors

1982 · Robert H. Springer, M. B. Scholten, et al. · Journal of Medicinal Chemistry · 31

Pyrimidines. XVIII. 2,4-Diamino-5-nitro-6-arylaminopyrimidines. Nitration Study of 2,4-Diamino-6-chloropyrimidine and a Literature Correction1

1966 · Darrell E. O'Brien, C. C. Cheng, et al. · Journal of Medicinal Chemistry · 23

Pyrimidines. XIII. 2‐ and 6‐substituted 4‐pyrimidinecarboxylic acids

1964 · G. Doyle Daves, Darrell E. O'Brien, et al. · Journal of Heterocyclic Chemistry · 20

Synthesis of unsymmetrical 2,4‐dialkylpyrazolo[1,5‐a]‐1,3,5‐triazines

1974 · Thomas Novinson, Keitaro Senga, et al. · Journal of Heterocyclic Chemistry · 17

Synthesis of 1,3‐dialkylpyrazolo [1,5‐a]‐1,3,5‐triazine‐2,4‐diones isomers of 1,3‐dialkylxanthines

1975 · Keitaro Senga, Joze Kobe, et al. · Journal of Heterocyclic Chemistry · 15

The synthesis of certain 5,7‐Dihydroxyimidazo[1,2‐a| pyrimidines

1973 · Ravindra Pralap Rao, Roland K. Robins, et al. · Journal of Heterocyclic Chemistry · 14

Synthesis of 3‐hydroxy‐2,1‐benzisothiazole

1973 · Anthony H. Albert, Roland K. Robins, et al. · Journal of Heterocyclic Chemistry · 14

Potential Purine Antagonists. XVII. Preparation of Some 6-Alkylthiopurines and 4-Alkylthiopyrazolo[3,4-d]pyrimidines

1959 · Henry Koppel, Darrell O'Brien, et al. · The Journal of Organic Chemistry · 14

Pyrimidines. XIX. Pyrimido[4,5‐e]dihydro‐1,3‐oxazines and related compounds

1967 · Darrell E. O'Brien, Louis T. Weinstock, et al. · Journal of Heterocyclic Chemistry · 13

A novel rearrangement of 3‐cyanopyrazolo[1,5‐a]pyrimidine to a pyrazolo[3,4‐d]pyrimidine

1973 · Thomas Novinson, Roland K. Robins, et al. · Journal of Heterocyclic Chemistry · 11

Folic acid analogs. I. p-[[(2,4-Diamino-5-pyrimidinyl)methyl]amino]benzoyl-L-glutamic acid and related compounds

1968 · Louis T. Weinstock, Darrell E. O'Brien, et al. · Journal of Medicinal Chemistry · 11

Pyrimidines. XXII. 2,4-Diamino-6-arylamino-5-pyrimidinecarboxaldehydes and related compounds

1968 · Darrell E. O'Brien, Louis T. Weinstock, et al. · Journal of Medicinal Chemistry · 11

Synthesis of 2,4‐dimethylpyrazolo[1,5‐a]‐1,3,5‐triazine

1973 · Anthony H. Albert, Roland K. Robins, et al. · Journal of Heterocyclic Chemistry · 10

Synthesis and Antitumor Activity of 9-Substituted Nitrogen Mustard Derivatives of 6-Alkylthiopurines1,2

1965 · Darrell E. O'Brien, James D. Westover, et al. · Journal of Medicinal Chemistry · 10

Pyrimidines. XI. Structural Variations of 2,4-Diamino-6-(halogenoanilino)-5-nitrosopyrimidines1

1963 · Darrell E. O'Brien, Fred Baiocchi, et al. · Journal of Medicinal Chemistry · 10

Synthesis of certain imidazo[2,1‐f] pyrazolo[3,4‐d] pyrimidines

1975 · Keitaro Senga, Roland K. Robins, et al. · Journal of Heterocyclic Chemistry · 9

Works count: 37

Citation count: 730

H-index: 14

I10-index: 24