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Xianchi Dong

N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2
2021 · Fang Tian, Bei Tong, et al. · eLife · 395
Force interacts with macromolecular structure in activation of TGF-β
2017 · Xianchi Dong, Bo Zhao, et al. · Nature · 279
GARP regulates the bioavailability and activation of TGFβ
2012 · Rui Wang, Jianghai Zhu, et al. · Molecular Biology of the Cell · 188
Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3
2006 · Peng Zhang, Jiamu Du, et al. · Nucleic Acids Research · 162
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Structural determinants of integrin β-subunit specificity for latent TGF-β
2014 · Xianchi Dong, Nathan E Hudson, et al. · Nature Structural & Molecular Biology · 140
Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus
2017 · Abhay Kotecha, Quan Wang, et al. · Nature Communications · 97
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The von Willebrand factor D′D3 assembly and structural principles for factor VIII binding and concatemer biogenesis
2019 · Xianchi Dong, Nina C. Leksa, et al. · Blood · 84
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αVβ3 Integrin Crystal Structures and Their Functional Implications
2012 · Xianchi Dong, Li-Zhi Mi, et al. · Biochemistry · 79
Structural Basis of Regulation of von Willebrand Factor Binding to Glycoprotein Ib
2014 · Mark A. Blenner, Xianchi Dong, et al. · Journal of Biological Chemistry · 76
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Molecular Basis of the Acceleration of the GDP-GTP Exchange of Human Ras Homolog Enriched in Brain by Human Translationally Controlled Tumor Protein
2009 · Xianchi Dong, Bei Yang, et al. · Journal of Biological Chemistry · 72
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Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36
2008 · Bingfa Sun, Jing Hong, et al. · Journal of Biological Chemistry · 64
The Third dose of CoronVac vaccination induces broad and potent adaptive immune responses that recognize SARS-CoV-2 Delta and Omicron variants
2022 · Yuxin Chen, Lin Chen, et al. · Emerging Microbes & Infections · 55
Prodomain–growth factor swapping in the structure of pro-TGF-β1
2017 · Bo Zhao, Shutong Xu, et al. · Journal of Biological Chemistry · 55
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De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8
2023 · Anindya Roy, Lei Shi, et al. · Nature Communications · 52
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A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
2011 · Minyun Zhou, Xianchi Dong, et al. · Blood · 51
Atypical interactions of integrin α V β 8 with pro-TGF-β1
2017 · Jianchuan Wang, Xianchi Dong, et al. · Proceedings of the National Academy of Sciences · 44
SWR1 Complex Poises Heterochromatin Boundaries for Antisilencing Activity Propagation
2010 · Bo O. Zhou, Shan-Shan Wang, et al. · Molecular and Cellular Biology · 42
Fusion surface structure, function, and dynamics of gamete fusogen HAP2
2018 · Juan Feng, Xianchi Dong, et al. · eLife · 40
Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
2008 · Ning Shen, Minyu Zhou, et al. · Nucleic Acids Research · 40
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S373P Mutation Stabilizes the Receptor-Binding Domain of the Spike Protein in Omicron and Promotes Binding
2023 · Bin Zheng, Yuelong Xiao, et al. · JACS Au · 32
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Specific high affinity interaction of Helicobacter pylori CagL with integrin αVβ6 promotes type IV secretion of CagA into human cells
2019 · Maren Buß, Nicole Tegtmeyer, et al. · FEBS Journal · 23
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Molecular modeling of purinergic receptor P2Y12 and interaction with its antagonists
2006 · Chenyang Zhan, Jie Yang, et al. · Journal of Molecular Graphics and Modelling · 23
High integrin α V β 6 affinity reached by hybrid domain deletion slows ligand-binding on-rate
2018 · Xianchi Dong, Bo Zhao, et al. · Proceedings of the National Academy of Sciences · 22
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Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
2010 · Minyun Zhou, Xianchi Dong, et al. · Nucleic Acids Research · 21
Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase
2009 · Xianchi Dong, Minyun Zhou, et al. · Nucleic Acids Research · 18
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Works count: 51
Citation count: 2,257
H-index: 22
I10-index: 27
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