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Nicola C. Hughes

Observed names: N C Hughes, N. C. Hughes, N.C. Hughes, Nicola C Hughes, Nicola Hughes
OpenAlex ID: A5111781644
Human acetyltransferase polymorphisms
1997 · Denis M Grant, Nicola C Hughes, et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 263
Determination of carryover and contamination for mass spectrometry-based chromatographic assays
2007 · Nicola C. Hughes, Ernest Y. K. Wong, et al. · The AAPS Journal · 134
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Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe
1998 · Nicola C. Hughes, Susan A. Janezic, et al. · Pharmacogenetics · 131
The 2nd Calibration and Validation Group Workshop on Recent Issues in Good Laboratory Practice Bioanalysis
2009 · Natasha Savoie, Brian P Booth, et al. · Bioanalysis · 95
Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas
1998 · Henry J. Lin, Nicole M. Probst-Hensch, et al. · Pharmacogenetics · 77
Covalent binding of dibenzpyrenes and benzo[a]Pyrene to DNA: evidence for synergistic and inhibitory interactions when applied in combination to mouse skin
1990 · N.C. Hughes, D.H. Phillips · Carcinogenesis · 66
2015 White Paper on Recent Issues in Bioanalysis: Focus on New Technologies and Biomarkers (Part 2 – Hybrid LBA/LCMS and Input from Regulatory Agencies)
2015 · Brad Ackermann, Hendrik Neubert, et al. · Bioanalysis · 57
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Assessing the Matrix Effects of Hemolyzed Samples in Bioanalysis
2009 · Nicola C Hughes, Navgeet Bajaj, et al. · Bioanalysis · 57
Recommendations on qPCR/ddPCR Assay Validation by GCC
2022 · Mark Wissel, Martin Poirier, et al. · Bioanalysis · 54
2016 White Paper on Recent Issues in Bioanalysis: Focus on Biomarker Assay Validation (BAV) (Part 1 – Small Molecules, Peptides and Small Molecule Biomarkers by LCMS)
2016 · Eric Yang, Jan Welink, et al. · Bioanalysis · 48
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2017 White Paper on Recent Issues in Bioanalysis: Aren’t Bmv Guidance/Guidelines ‘ Scientific ’? (Part 1 – LCMS: Small Molecules, Peptides and Small Molecule Biomarkers)
2017 · Jan Welink, Eric Yang, et al. · Bioanalysis · 44
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2016 White Paper on Recent Issues in Bioanalysis: Focus on Biomarker Assay Validation (BAV): (Part 2 – Hybrid LBA/LCMS and Input from Regulatory Agencies)
2016 · An Song, Anita Lee, et al. · Bioanalysis · 44
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2015 White Paper on Recent Issues in Bioanalysis: Focus on New Technologies and Biomarkers (Part 1 – Small Molecules by LCMS)
2015 · Jan Welink, Eric Fluhler, et al. · Bioanalysis · 43
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Covalent binding of polycyclic aromatic hydrocarbon components of coal tar to DNA in mouse skin
1993 · N.C. Hughes, W. Pfau, et al. · Carcinogenesis · 41
Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects
2001 · Susan A. J. Vaziri, Nicola C. Hughes, et al. · Pharmacogenetics · 40
2018 White Paper on Recent Issues in Bioanalysis: ‘A Global Bioanalytical Community Perspective on Last Decade of Incurred Samples Reanalysis (ISR)’ (Part 1 – Small Molecule Regulated Bioanalysis, Small Molecule Biomarkers, Peptides & Oligonucleotide Bioanalysis)
2018 · Jan Welink, Yuanxin Xu, et al. · Bioanalysis · 39
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2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome ( Part 1 –Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos)
2021 · Hendrik Neubert, Stephen C Alley, et al. · Bioanalysis · 35
Structure, Conformations, and Repair of DNA Adducts from Dibenzo[a,l]pyrene: 32P-Postlabeling and Fluorescence Studies
1998 · Ryszard Jankowiak, Freek Ariese, et al. · Chemical Research in Toxicology · 32
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Accurate mass measurement at enhanced mass‐resolution on a triple quadrupole mass‐spectrometer for the identification of a reaction impurity and collisionally‐induced fragment ions of cabergoline
2003 · Gary Paul, Witold Winnik, et al. · Rapid Communications in Mass Spectrometry · 23
32P-Postlabelling analysis of the covalent binding of benzo[ghi]perylene to DNA in vivo and in vitro
1993 · N.C. Hughes, D.H. Phillips · Carcinogenesis · 22
High‐sensitivity quantitation of cabergoline and pergolide using a triple‐quadrupole mass spectrometer with enhanced mass‐resolution capabilities
2003 · Nicola Hughes, Witold Winnik, et al. · Journal of Mass Spectrometry · 20
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Ciprofloxacin Prolonged‐Release Tablets Do Not Affect Warfarin Pharmacokinetics and Pharmacodynamics
2007 · Carla Washington, S. Y. Eddie Hou, et al. · The Journal of Clinical Pharmacology · 19
9th GCC Closed Forum: Capa in Regulated Bioanalysis; Method Robustness, Biosimilars, Preclinical Method Validation, Endogenous Biomarkers, Whole Blood Stability, Regulatory Audit Experiences and Electronic Laboratory Notebooks
2016 · Roger Hayes, Richard LeLacheur, et al. · Bioanalysis · 17
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Recommendations on ELISpot Assay Validation by the GCC
2022 · Rafiq Islam, Jennifer Vance, et al. · Bioanalysis · 16
Recommendations for Classification of Commercial LBA Kits for Biomarkers in Drug Development From the GCC for Bioanalysis
2019 · Rafiq Islam, Sumit Kar, et al. · Bioanalysis · 16
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Works count: 32
Citation count: 1,519
H-index: 20
I10-index: 30
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