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J. Bichler

Persistent thrombin generation in humans during specific thrombin inhibition with hirudin.
1994 · P Zoldhelyi, J Bichler, et al. · Circulation · 57
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PK ‐guided personalized prophylaxis with Nuwiq® (human‐cl rh FVIII ) in adults with severe haemophilia A
2017 · T. Lissitchkov, L. Rusen, et al. · Haemophilia · 54
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Pharmacokinetics and pharmacodynamics of hirudin in man after single subcutaneous and intravenous bolus administration.
1988 · J Bichler, B Fichtl, et al. · PubMed · 47
Hirudin, a new therapeutic tool?
1991 · J. Bichler, H. Fritz · Annals of Hematology · 45
Novel, human cell line‐derived recombinant factor VIII (human‐cl rhFVIII; Nuwiq ® ) in adults with severe haemophilia A: efficacy and safety
2015 · T. Lissitchkov, K. Hampton, et al. · Haemophilia · 39
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Weak allergenicity of recombinant hirudin CGP 39393 (REVASC) in immunocompetent volunteers. The European Hirudin in Thrombosis Group (HIT Group).
1994 · P Close, J Bichler, et al. · PubMed · 38
Prophylaxis vs. on‐demand treatment with Nuwiq® (Human‐cl rh FVIII ) in adults with severe haemophilia A
2015 · A. Tiede, J. Oldenburg, et al. · Haemophilia · 35
Individual thrombin generation and spontaneous bleeding rate during personalized prophylaxis with Nuwiq ® (human‐cl rh FVIII ) in previously treated patients with severe haemophilia A
2018 · Y. Dargaud, C. Negrier, et al. · Haemophilia · 34
Development of a chromogenic substrate assay for the determination of hirudin in plasma
1991 · M. Spannagl, J. Bichler, et al. · Blood Coagulation & Fibrinolysis · 32
Studies for revealing a possible sensitization to hirudin after repeated intravenous injections in baboons
1991 · J. Bichler, R. Gemmerli, et al. · Thrombosis Research · 30
Determination of thrombin - hirudin complex in plasma with an enzyme-linked immunosorbent assay
1991 · J. Bichler, M. Siebeck, et al. · Blood Coagulation & Fibrinolysis · 29
Catabolism of hirudin and thrombin-hirudin complexes in the rat
1993 · J Bichler, J W Baynes, et al. · Biochemical Journal · 16
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Long‐term tolerability, immunogenicity and efficacy of Nuwiq® (human‐cl rhFVIII) in children with severe haemophilia A
2018 · A. Klukowska, T. Szczepański, et al. · Haemophilia · 15
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Pharmacokinetics and safety of recombinant anti‐RhD in healthy RhD‐negative male volunteers
2004 · J. Bichler, M. O. Spycher, et al. · Transfusion Medicine · 13
Efficacy and safety of Nuwiq® (human‐cl rh FVIII ) in patients with severe haemophilia A undergoing surgical procedures
2017 · N. Zozulya, C. M. Kessler, et al. · Haemophilia · 10
Pharmacokinetics, Effect on Clotting Tests and Assessment of the Immunogenic Potential of Hirudin after a Single Subcutaneous or Intravenous Bolus Administration in Man
2009 · J. Bichler, M. Siebeck, et al. · Haemostasis · 9
Safety and Tolerability of a New Intravenous Immunoglobulin Product (Privigen) Administered at High Infusion Rates
2008 · J.A. Church, R.P. Nelson, et al. · Journal of Allergy and Clinical Immunology · 1
Experience with Nuwiq (R) in clinical trials with previously treated paediatric and adult patients
2016 · Robert Klamroth, J. Bichler, et al.
Title Page / Table of Contents, Vol. 21, Supplement 1, 1991
2009 · J.W. Fenton II, G.B. Villanueva, et al. · Haemostasis
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Author Index, Vol. 21, 1991
2009 · J.W. Fenton II, G.B. Villanueva, et al. · Haemostasis
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Pharmacokinetics of a Novel Liquid 10% Immunoglobulin Preparation for Intravenous Use (Privigen) in Subjects with Primary Immunodeficiency
2008 · R.L. Wasserman, J.A. Church, et al. · Journal of Allergy and Clinical Immunology
In vitro characterization of rhophylac®, a new liquid anti‐d immunoglobulin product for IV and IM application
2000 · M. Stucki, H. Abegglen, et al. · International Journal of Gynecology & Obstetrics
Hirudin verhindert die intravasculäre Gerinnung im Endotoxinschock des Schweins
1988 · M. Siebeck, H. Hoffmann, et al. · Springer eBooks
Works count: 24
Citation count: 504
H-index: 13
I10-index: 15
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