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Silvia A. Mandel
Observed names:
S Mandel,
S. MANDEL,
S. Mandel,
S.A. Mandel,
SILVIA MANDEL,
Silvia A Mandel,
Silvia Mandel
show all 7
Institution:
University of Haifa
Observed institutions:
University of Bonn,
Tel Aviv University,
Technion – Israel Institute of Technology,
Teva Pharmaceuticals (Israel),
Rappaport Family Institute for Research in the Medical Sciences,
University of Haifa
show all 6
OpenAlex ID:
A5111809134
PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
2010
·
Bin Zheng
, Zhixiang Liao
, et al.
·
Science Translational Medicine
·
857
Green tea polyphenol (–)‐epigallocatechin‐3‐gallate prevents N ‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced dopaminergic neurodegeneration
2001
·
Yona Levites
, Orly Weinreb
, et al.
·
Journal of Neurochemistry
·
567
Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases
2004
·
Orly Weinreb
, Silvia Mandel
, et al.
·
The Journal of Nutritional Biochemistry
·
506
Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases
2004
·
Silvia Mandel
, Moussa B.H Youdim
·
Free Radical Biology and Medicine
·
445
Involvement of Protein Kinase C Activation and Cell Survival/ Cell Cycle Genes in Green Tea Polyphenol (−)-Epigallocatechin 3-Gallate Neuroprotective Action
2002
·
Yona Levites
, Tamar Amit
, et al.
·
Journal of Biological Chemistry
·
417
Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (‐)‐epigallocatechin‐3‐gallate: implications for neurodegenerative diseases
2004
·
Silvia Mandel
, Orly Weinreb
, et al.
·
Journal of Neurochemistry
·
379
Neuroprotection and neurorescue against Aβ toxicity and PKC‐dependent release of non‐amyloidogenic soluble precursor protein by green tea polyphenol (‐)‐epigallocatechin‐3‐gallate
2003
·
Yona Levites
, Tamar Amit
, et al.
·
The FASEB Journal
·
373
Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes
2004
·
E. Gr�nblatt
, S. Mandel
, et al.
·
Journal of Neural Transmission
·
356
The relevance of iron in the pathogenesis of Parkinson’s disease
2010
·
Jeswinder Sian‐Hülsmann
, Silvia Mandel
, et al.
·
Journal of Neurochemistry
·
352
PDF
Multifunctional Activities of Green Tea Catechins in Neuroprotection
2005
·
Silvia A. Mandel
, Yael Avramovich-Tirosh
, et al.
·
Neurosignals
·
347
Green tea catechins as brain‐permeable, natural iron chelators‐antioxidants for the treatment of neurodegenerative disorders
2006
·
Silvia Mandel
, Tamar Amit
, et al.
·
Molecular Nutrition & Food Research
·
291
Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-κB) activation and cell death by tea extracts in neuronal cultures11Abbreviations: BT, Black Tea; EMSA, Electromobility Shift Assay; EGCG, (-)-Epigallocatechin-3-gallate; GT, Green Tea; NB SH-SY5Y cells, Human neuroblastoma SH-SY5Y cells; 6-OHDA, 6-hydroxydopamine; IL, Interleukin; LDH, Lactate Dehydrogenase; MPTP, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NF-κB, nuclear factor-κB; OS, Oxidative Stress; PD, Parkinson’s Disease; ROS, Reactive Oxygen Species; SNPC, Substantia Nigra Pars Compacta; TBARS, thiobarbituric acid reactive substances.
2002
·
Yona Levites
, Moussa B.H. Youdim
, et al.
·
Biochemical Pharmacology
·
291
Gene expression analysis in N‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R‐apomorphine
2001
·
Edna Grünblatt
, Silvia Mandel
, et al.
·
Journal of Neurochemistry
·
246
Neuroprotective molecular mechanisms of (−)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties
2009
·
Orly Weinreb
, Tamar Amit
, et al.
·
Genes & Nutrition
·
242
PDF
Neuroprotective Strategies in Parkinson???s Disease
2003
·
Silvia Mandel
, Edna Gr??nblatt
, et al.
·
CNS Drugs
·
237
Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases
2008
·
Silvia A. Mandel
, Tamar Amit
, et al.
·
CNS Neuroscience & Therapeutics
·
221
PDF
Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators
2013
·
Orly Weinreb
, Silvia Mandel
, et al.
·
Free Radical Biology and Medicine
·
190
Reduction of iron‐regulated amyloid precursor protein and β‐amyloid peptide by (–)‐epigallocatechin‐3‐gallate in cell cultures: implications for iron chelation in Alzheimer's disease
2006
·
L. Reznichenko
, T. Amit
, et al.
·
Journal of Neurochemistry
·
189
PDF
Cell Signaling Pathways and Iron Chelation in the Neurorestorative Activity of Green Tea Polyphenols: Special Reference to Epigallocatechin Gallate (EGCG)
2008
·
Silvia A. Mandel
, Tamar Amit
, et al.
·
Journal of Alzheimer s Disease
·
173
Iron and α-Synuclein in the Substantia Nigra of MPTP-Treated Mice: Effect of Neuroprotective Drugs R-Apomorphine and Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate
2004
·
Silvia Mandel
, Gila Maor
, et al.
·
Journal of Molecular Neuroscience
·
171
Iron dysregulation in Alzheimer's disease: Multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents
2007
·
Silvia Mandel
, Tamar Amit
, et al.
·
Progress in Neurobiology
·
164
Gene Expression Profiling of Sporadic Parkinson's Disease Substantia Nigra Pars Compacta Reveals Impairment of Ubiquitin-Proteasome Subunits, SKP1A, Aldehyde Dehydrogenase, and Chaperone HSC-70
2005
·
SILVIA MANDEL
, EDNA GRUNBLATT
, et al.
·
Annals of the New York Academy of Sciences
·
158
Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives
2005
·
Silvia Mandel
, Orly Weinreb
, et al.
·
Brain Research Reviews
·
157
Green tea polyphenol (–)‐epigallocatechin‐3‐gallate induces neurorescue of long‐term serum‐deprived PC12 cells and promotes neurite outgrowth
2005
·
L. Reznichenko
, T. Amit
, et al.
·
Journal of Neurochemistry
·
151
Targeting Multiple Neurodegenerative Diseases Etiologies with Multimodal-Acting Green Tea Catechins
2008
·
Silvia A. Mandel
, Tamar Amit
, et al.
·
Journal of Nutrition
·
148
PDF
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Works count:
143
Citation count:
11,680
H-index:
55
I10-index:
95
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