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Matthew C. Coffey

Reovirus Therapy of Tumors with Activated Ras Pathway
1998 · Matthew C. Coffey, James E. Strong, et al. · Science · 750
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade
2018 · Adel Samson, Karen J. Scott, et al. · Science Translational Medicine · 374
Reovirus Oncolysis of Human Breast Cancer
2002 · Kara L. Norman, Matthew C. Coffey, et al. · Human Gene Therapy · 174
Intravenous administration of Reolysin®, a live replication competent RNA virus is safe in patients with advanced solid tumors
2009 · Radharani Gollamudi, Mohammad H. Ghalib, et al. · Investigational New Drugs · 149
Systemic reovirus therapy of metastatic cancer in immune-competent mice.
2003 · Kensuke Hirasawa, Sandra G Nishikawa, et al. · PubMed · 145
Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity
2009 · E J Ilett, R J Prestwich, et al. · Gene Therapy · 123
Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells
2009 · Shizuko Sei, Jodie K Mussio, et al. · Molecular Cancer · 118
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Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma
2008 · F Errington, C L White, et al. · Gene Therapy · 105
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Hsp90 Phosphorylation Is Linked to Its Chaperoning Function
2001 · Ya-Guang Zhao, Ross Gilmore, et al. · Journal of Biological Chemistry · 98
Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization
2011 · Elizabeth J. Ilett, Montserrat Bárcena, et al. · Clinical Cancer Research · 97
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A phase II study of REOLYSIN® (pelareorep) in combination with carboplatin and paclitaxel for patients with advanced malignant melanoma
2017 · Devalingam Mahalingam, Christos Fountzilas, et al. · Cancer Chemotherapy and Pharmacology · 94
Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer
2016 · Adel Samson, Matthew J Bentham, et al. · Gut · 78
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Antibody-Neutralized Reovirus Is Effective in Oncolytic Virotherapy
2018 · Robert A. Berkeley, Lynette P. Steele, et al. · Cancer Immunology Research · 75
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Reovirus-based therapy for cancer
2009 · Kevin Kelly, Steffan Nawrocki, et al. · Expert Opinion on Biological Therapy · 70
Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non–small cell lung cancer patients with K RAS‐activated tumors
2015 · Miguel A. Villalona‐Calero, Elaine Lam, et al. · Cancer · 69
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Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan
2014 · Radhashree Maitra, Raviraja Seetharam, et al. · Oncotarget · 62
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Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy
2012 · V Roulstone, K Twigger, et al. · Gene Therapy · 56
Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples
2012 · Gerard J Nuovo, Michela Garofalo, et al. · Modern Pathology · 48
Co‐translational trimerization of the reovirus cell attachment protein.
1996 · R. Gilmore, M. C. Coffey, et al. · The EMBO Journal · 46
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Controlled infection with a therapeutic virus defines the activation kinetics of human natural killer cellsin vivo
2014 · Y M El-Sherbiny, T D Holmes, et al. · Clinical & Experimental Immunology · 37
Elucidation of Pelareorep Pharmacodynamics in A Phase I Trial in Patients with KRAS -Mutated Colorectal Cancer
2020 · Sanjay Goel, Allyson J. Ocean, et al. · Molecular Cancer Therapeutics · 35
Oncolytic reovirus therapy: Pilot study in dogs with spontaneously occurring tumours
2017 · C. C. Hwang, M. Igase, et al. · Veterinary and Comparative Oncology · 27
Active Participation of Hsp90 in the Biogenesis of the Trimeric Reovirus Cell Attachment Protein ς1
1998 · Ross Gilmore, Matthew C. Coffey, et al. · Journal of Biological Chemistry · 26
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C-terminal Trimerization, but Not N-terminal Trimerization, of the Reovirus Cell Attachment Protein Is a Posttranslational and Hsp70/ATP-dependent Process
1996 · Gustavo Leone, Matthew C. Coffey, et al. · Journal of Biological Chemistry · 26
Toll-like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer
2017 · Radhashree Maitra, Titto Augustine, et al. · Oncotarget · 25
Works count: 78
Citation count: 3,028
H-index: 25
I10-index: 30
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