Author

ISAMI TAKAHASHI

Observed names: I Takahashi, I. TAKAHASHI, Isami TAKAHASHI, Isami Takahashi

Observed institution: Kyowa Kirin (Japan)

OpenAlex ID: A5111859048

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 · Tatsuya Tamaoki, Hisayo Nomoto, et al. · Biochemical and Biophysical Research Communications · 2,456

Wortmannin, a microbial product inhibitor of myosin light chain kinase.

1992 · S Nakanishi, S Kakita, et al. · Journal of Biological Chemistry · 429

Inhibition of protein kinase C by calphostin C is light-dependent

1991 · Robert F. Bruns, F.Dean Miller, et al. · Biochemical and Biophysical Research Communications · 362

Staurosporine inhibits tyrosine-specific protein kinase activity of Rous sarcoma virus transforming protein p60.

1987 · HIROFUMI NAKANO, EIJI KOBAYASHI, et al. · The Journal of Antibiotics · 261

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Hypericin and pseudohypericin specifically inhibit protein kinase C: Possible relation to their antiretroviral activity

1989 · Isami Takahashi, Satoshi Nakanishi, et al. · Biochemical and Biophysical Research Communications · 215

Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp.

1990 · MICHIO ICHIMURA, TATSUHIRO OGAWA, et al. · The Journal of Antibiotics · 204

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Duocarmycin A, a new antitumor antibiotic from Streptomyces.

1988 · ISAMI TAKAHASHI, KEI-ICHI TAKAHASHI, et al. · The Journal of Antibiotics · 195

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UCN-01, a selective inhibitor of protein kinase C from Streptomyces.

1987 · ISAMI TAKAHASHI, EIJI KOBAYASHI, et al. · The Journal of Antibiotics · 186

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UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities.

1989 · ISAMI TAKAHASHI, YUTAKA SAITOH, et al. · The Journal of Antibiotics · 157

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DC 107, a novel antitumor antibiotic produced by a Streptomyces sp.

1989 · MITSUNOBU HARA, ISAMI TAKAHASHI, et al. · The Journal of Antibiotics · 125

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UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation.

1989 · ISAMI TAKAHASHI, Kozo ASANO, et al. · The Journal of Antibiotics · 107

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Duocarmycins, Potent Antitumor Antibiotics Produced by Streptomyces sp. Structures and Chemistry.

1995 · Tohru YASUZAWA, Ken'ichi MUROI, et al. · Chemical and Pharmaceutical Bulletin · 97

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Duocarmycins, new antitumor antibiotics produced by Streptomyces; Producing organisms and improved production.

1991 · MICHIO ICHIMURA, TATSUHIRO OGAWA, et al. · The Journal of Antibiotics · 94

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Selective Inhibition of IL-Gene Expression by 2Trichostatin A, a Potent Inhibitor of Mammalian Histone Deacetylase.

1996 · ISAMI TAKAHASHI, HIROMASA MIYAJI, et al. · The Journal of Antibiotics · 72

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Lymphostin (LK6-A), a Novel Immunosuppressant from Streptomyces sp. KY11783: Taxonomy of the Producing Organism, Fermentation, Isolation and Biological Activities.

1997 · HIROYUKI NAGATA, KEIKO OCHIAI, et al. · The Journal of Antibiotics · 57

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Structure of duocarmycin SA, a potent antitumor antibiotic.

1991 · TOHRU YASUZAWA, YUTAKA SAITOH, et al. · The Journal of Antibiotics · 49

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Potent selective inhibition of 7-O-methyl UCN-01 against protein kinase C.

1990 · I Takahashi, E Kobayashi, et al. · Journal of Pharmacology and Experimental Therapeutics · 44

Enzymatic Characterization of Human α1,3-Fucosyltransferase Fuc-TVII Synthesized in a B Cell Lymphoma Cell Line

1997 · Katsumi Shinoda, Yoshikazu Morishita, et al. · Journal of Biological Chemistry · 33

Calphostin (UCN1028) and calphostin related compounds, a new class of specific and potent inhibitors of protein kinase C.

1990 · T Tamaoki, I Takahashi, et al. · PubMed · 31

The reversible DNA-alkylating activity of duocarmycin and its analogues

1994 · Akira Asai, Satoru Nagamura, et al. · Nucleic Acids Research · 27

High-Level Expression and Purification of a Recombinant Human α-1,3-Fucosyltransferase in Baculovirus-Infected Insect Cells

1997 · Akeo Shinkai, Katsumi Shinoda, et al. · Protein Expression and Purification · 23

GT32-B New 20-Membered Macrocyclic Lactam Antibiotic.

1997 · ISAMI TAKAHASHI, YASHUSHI ODA, et al. · The Journal of Antibiotics · 23

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Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.

1993 · M Ichimura, T Ogawa, et al. · PubMed · 19

DC92-B, a new antitumor antibiotic from Actinomadura.

1988 · ISAMI TAKAHASHI, KEI-ICHI TAKAHASHI, et al. · The Journal of Antibiotics · 19

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DC-86-M, a novel antitumor antibiotic. II. Structure determination and biological activities.

1986 · KEIICHI TAKAHASHI, ISAMI TAKAHASHI, et al. · The Journal of Antibiotics · 19

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Works count: 34

Citation count: 5,359

H-index: 22

I10-index: 28