Author

Jeffrey R. Jasper

Observed names: J Jasper, J R Jasper, J. Jasper, J. R. JASPER, J. R. Jasper, J.R. Jasper, JEFFREY R. JASPER, Jasper, Jeff, Jeff R. Jasper, Jeffrey Jasper, Jeffrey R Jasper, Jeffrey R. JASPER

Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), Roche (United States), Albert Einstein College of Medicine, City Of Hope National Medical Center, Harvard University, Jacobi Medical Center, University of California San Diego, Revolution Medicines (United States), Dana-Farber Cancer Institute, Theravance Biopharma (United States), Stanford Medicine, Cytokinetics (United States), Altos Therapeutics (United States), Stanford University

OpenAlex ID: A5111862234

Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.

1996 · D K Rohrer, K H Desai, et al. · Proceedings of the National Academy of Sciences · 310

Assessment of the role of α 2 ‐adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice

1997 · J. C. Hunter, D. J. Fontana, et al. · British Journal of Pharmacology · 294

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Pharmacological pleiotropism of the human recombinant α1A‐adrenoceptor: implications for α1‐adrenoceptor classification

1997 · Anthony P D W Ford, Donald V Daniels, et al. · British Journal of Pharmacology · 219

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RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

1996 · A P Ford, N F Arredondo, et al. · Molecular Pharmacology · 195

The 5-HT7 receptor: orphan found

1997 · Richard M. Eglen, Jeffrey R. Jasper, et al. · Trends in Pharmacological Sciences · 162

Ligand Efficacy and Potency at Recombinant α2 Adrenergic Receptors

1998 · Jeffrey R Jasper, John D Lesnick, et al. · Biochemical Pharmacology · 157

Stoichiometry of receptor‐G s ‐adenylate cyclase interactions

1991 · Adawia A. Alousi, Jeffrey R. Jasper, et al. · The FASEB Journal · 141

Stimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranes.

1989 · L A Ransnäs, P Svoboda, et al. · Proceedings of the National Academy of Sciences · 138

Cloning, expression and pharmacology of a truncated splice variant of the human 5‐HT7 receptor (h5‐HT7(b))

1997 · J. R. Jasper, A. Kosaka, et al. · British Journal of Pharmacology · 128

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Contribution of α2 receptor subtypes to nerve injury‐induced pain and its regulation by dexmedetomidine

2001 · Annika B Malmberg, Linda R Hedley, et al. · British Journal of Pharmacology · 100

A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M2 Muscarinic Receptor

2007 · Tod Steinfeld, Mathai Mammen, et al. · Molecular Pharmacology · 96

Cardiovascular effects of rilmenidine, moxonidine and clonidine in conscious wild‐type and D79N α2A‐adrenoceptor transgenic mice

1999 · Q‐M Zhu, J D Lesnick, et al. · British Journal of Pharmacology · 95

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Molecular cloning, genomic characterization and expression of novel human α1A‐adrenoceptor isoforms

1998 · David J Chang, Thomas K Chang, et al. · FEBS Letters · 80

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Human cloned α1A-adrenoceptor isoforms display α1L-adrenoceptor pharmacology in functional studies

1999 · Donald V. Daniels, Joel R. Gever, et al. · European Journal of Pharmacology · 74

The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure

2015 · Darren T. Hwee, Adam R. Kennedy, et al. · Journal of Pharmacology and Experimental Therapeutics · 69

Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy

2013 · Coen A. C. Ottenheijm, Danielle Buck, et al. · Brain · 64

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Fast Skeletal Muscle Troponin Activator tirasemtiv Increases Muscle Function and Performance in the B6SJL-SOD1G93A ALS Mouse Model

2014 · Darren T. Hwee, Adam Kennedy, et al. · PLoS ONE · 63

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Diaphragm Fiber Strength Is Reduced in Critically Ill Patients and Restored by a Troponin Activator

2014 · Pleuni E. Hooijman, Albertus Beishuizen, et al. · American Journal of Respiratory and Critical Care Medicine · 56

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Alteration in Gs-mediated signal transduction in S49 lymphoma cells treated with inhibitors of microtubules.

1993 · D. Leiber, J.R. Jasper, et al. · Journal of Biological Chemistry · 55

Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations

2013 · Josine Marieke de Winter, Danielle Buck, et al. · Journal of Medical Genetics · 52

Characterization of α2‐adrenoceptors mediating contraction of dog saphenous vein: identity with the human α2A subtype

1997 · S. J. MacLennan, L. A. Luong, et al. · British Journal of Pharmacology · 43

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Evolving concepts of partial agonism

1992 · Jeffrey R. Jasper, Paul A. Insel · Biochemical Pharmacology · 43

Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells

1995 · Jeffrey R. Jasper, C.Meacham Harrell, et al. · Life Sciences · 39

Fast skeletal muscle troponin activator CK‐2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction

2019 · Arthur J. Cheng, Darren T. Hwee, et al. · The Journal of Physiology · 38

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Tissue- and subunit-specific regulation of G-protein expression by hypo- and hyperthyroidism

1993 · Martina B. Michel-Reher, Gerhard Gross, et al. · Biochemical Pharmacology · 38

Works count: 79

Citation count: 3,352

H-index: 32

I10-index: 47